Flt3l

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Flt3l

Official Full Name FMS-like tyrosine kinase 3 ligand
Background FLT3L, also known as flt3 ligand, acts as a growth factor that increases the number of immune cells by activating the hematopoietic progenitors. It is a small molecule which also induces the mobilization of the hematopoietic progenitors and stem cells in
Synonyms Flt3l; FMS-like tyrosine kinase 3 ligand; Ly72L; Flt3lg; fms-related tyrosine kinase 3 ligand; flt3 ligand
    • Species :
    • Human
    • Macaca mulatta
    • Mouse
    • Source :
    • Barley Grain
    • CHO
    • E.coli
    • HEK293
    • HEK293T
    • Human Cell
    • Insect Cell
    • NSO
    • Tag :
    • Fc
    • His
    • T7
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Mouse Flt3l-02M Recombinant Mouse Flt3l Protein, His-tagged CHO His
    Mouse Flt3l-064M Recombinant Mouse Flt3l Protein E.coli
    Mouse Flt3l-3046M Recombinant Mouse Flt3l Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Human FLT3L-20H Recombinant Human FLT3L, His-tagged Barley Grain His
    Mouse Flt3l-03M Recombinant Mouse Flt3l E.coli N/A
    Mouse Flt3l-188M Recombinant Mouse FMS-like Tyrosine Kinase 3 Ligand NSO N/A
    Mouse Flt3l-4372M Recombinant Mouse Flt3l Protein E.coli N/A
    Mouse Flt3l-456M Recombinant Mouse Flt3l, Fc-tagged Human Cell Fc
    Mouse Flt3l-457M Recombinant Mouse Flt3l protein, His-tagged HEK293 His
    Mouse Flt3l-63M Recombinant Mouse Flt3l protein, His-tagged Insect Cell His
    Mouse Flt3l-762M Recombinant Mouse Flt3l protein, His & T7-tagged E.coli His/T7
    Mouse Flt3l-8704M Recombinant Mouse Flt3l, Fc tagged Human Cell Fc
    Mouse Flt3l-936M Recombinant Mouse Flt3l protein E.coli N/A
    Mouse FLT3LG-1387MCL Recombinant Mouse FLT3LG cell lysate Human Cell N/A
    Macaca mulatta FLT3-1229M Recombinant Macaca mulatta FLT3 Ligand E.coli N/A

    Flt3l involved in several pathways and played different roles in them. We selected most pathways Flt3l participated on our site, such as Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, Pathways in cancer, which may be useful for your reference. Also, other proteins which involved in the same pathway with Flt3l were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cytokine-cytokine receptor interaction EDAR; TNFRSF18; TNFRSF1A; TNFRSF17; IFNA14; IFNA5; XCL2; VEGFA; CXCL16; Flt3l
    Hematopoietic cell lineage CR2; ITGA4; CD22; HLA-DRB1; GP5; CD8B; TNF; ITGA2B; CD36; GYPA
    Pathways in cancer RALB; GRB2; DAPK1; ITGA6; SKP2; LAMA4; MLH1; MAPK9; GNG12; RXRB

    Flt3l has several biochemical functions, for example, cytokine activity, protein homodimerization activity, receptor tyrosine kinase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Flt3l itself. We selected most functions Flt3l had, and list some proteins which have the same functions with Flt3l. You can find most of the proteins on our site.

    Function Related Protein
    cytokine activity GDF6B; MSTNB; Cxcl15; GDF5; IL17A/F2; IFNG1-1; IL24; IL26; WNT5A; SCGB3A1
    protein homodimerization activity HPRT1; CCL5; CEP57; UBE4A; DGAT2; APOBEC3G; TESCA; ROPN1B; TMEM173; GSTM4
    receptor tyrosine kinase binding ELMO2; HYAL2; FIZ1; ANGPT4; GAS6; PLCG1; ANGPT2A; CPNE3; FNTA; PCNA

    Flt3l has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Flt3l here. Most of them are supplied by our site. Hope this information will be useful for your research of Flt3l.

    Ramos, MIP; Karpus, ON; et al. Absence of Fms-like tyrosine kinase 3 ligand (Flt3L) signalling protects against collagen-induced arthritis. ANNALS OF THE RHEUMATIC DISEASES 74:211-219(2015).
    Hodge, DL; Berthet, C; et al. IFN-gamma AU-rich element removal promotes chronic IFN-gamma expression and autoimmunity in mice. JOURNAL OF AUTOIMMUNITY 53:33-45(2014).

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