GSTP1 Protein, glutathione S-transferase pi 1


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Official Full Name glutathione S-transferase pi 1
Background Glutathione S-transferases (GSTs) are a family of isoenzymes that detoxify electrophiles through conjugation to thiol-reduced glutathione (GSH). Thus, they are critical in protecting cells from toxins (drugs, pesticides, carcinogens) and oxidative stress
Synonyms GSTP1; glutathione S-transferase pi 1; FAEES3, GST3; glutathione S-transferase P; GSTP; GSTP1-1; GST class-pi; deafness, X-linked 7; fatty acid ethyl ester synthase III; PI; DFN7; GST3; FAEES3
    • Species :
    • Cattle
    • Cynomolgus Monkey
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Human
    • Mammalian Cell
    • Wheat Germ
    • Yeast
    • Tag :
    • GST
    • His
    • SUMO
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Mouse GSTP1-1406M Recombinant Mouse GSTP1 Protein (2-210 aa), His-tagged Yeast His
    Human GSTP1-2550H Recombinant Human GSTP1 Protein (2-210 aa), His-tagged Yeast His
    Mouse GSTP1-540M Recombinant Mouse GSTP1 Protein (2-210 aa), His-SUMO-tagged E.coli His/SUMO
    Human GSTP1-1086H Recombinant Human GSTP1, His-tagged Human HIS
    Human GSTP1-250H Recombinant Human GSTP1 E.coli N/A
    Human GSTP1-4428H Recombinant Human GSTP1 Protein, GST-tagged Wheat Germ GST
    Human GSTP1-5709HCL Recombinant Human GSTP1 293 Cell Lysate HEK293 N/A
    Mouse Gstp1-29M Recombinant Mouse Gstp1 protein, His-tagged E.coli His
    Mouse GSTP1-7339M Recombinant Mouse GSTP1 Protein Mammalian Cell His
    Rat Gstp1-1493R Recombinant Rat Gstp1 protein, His-tagged E.coli His
    Cynomolgus Monkey GSTP1-580C Recombinant Cynomolgus GSTP1 Protein, His-tagged Mammalian Cell His
    Rhesus Macaque GSTP1-1997R Recombinant Rhesus monkey GSTP1 Protein, His-tagged Mammalian Cell His
    Zebrafish GSTP1-9254Z Recombinant Zebrafish GSTP1 Mammalian Cell His
    Cattle GSTP1-1491C Recombinant Cattle GSTP1 protein, His-tagged E.coli His

    GSTP1 involved in several pathways and played different roles in them. We selected most pathways GSTP1 participated on our site, such as Glutathione metabolism, Metabolism of xenobiotics by cytochrome P, Drug metabolism - cytochrome P, which may be useful for your reference. Also, other proteins which involved in the same pathway with GSTP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Glutathione metabolism G6PDX; GSTA4; GCLM; LAP3; GSTP1; RRM2; GSTT2B; MGST3; PGD; GSTT1B
    Metabolism of xenobiotics by cytochrome P UGT5G1; UGT2A2; GSTM1; GSTT1; UGT1A7; UGT1A2; UGT1A6; GSTA2; UGT1A6A; UGT1AB
    Drug metabolism - cytochrome P UGT1A2; MGST3; UGT2A2; GSTA3; UGT1AB; MAOB; FMO6P; ALDH3B2; AOX2P; UGT1A6
    Pathways in cancer RALGDS; HHIP; CKS2; STAT5B; PLCG2; FZD3; CTNNA3; RET; PTCH1; PRKCB
    Chemical carcinogenesis ALDH3A1; CYP2C54; UGT1A3; MGST3; CYP2C37; UGT1A9; ADH2-2; CYP3A5; AKR1C2; MGST1
    Prostate cancer TP53; ARID1A; CCND1; CASP9; IKBKB; RAF1; FGFR1; IKBKG; FOXA1; HSP90AB1

    GSTP1 has several biochemical functions, for example, JUN kinase binding, S-nitrosoglutathione binding, dinitrosyl-iron complex binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GSTP1 itself. We selected most functions GSTP1 had, and list some proteins which have the same functions with GSTP1. You can find most of the proteins on our site.

    Function Related Protein
    JUN kinase binding MAD2L2; MAPK8IP3; SPAG9; GSTP1; SPAG9A; PTK2
    S-nitrosoglutathione binding GSTP1; GSTP2
    dinitrosyl-iron complex binding GSTP1; GSTP2
    glutathione transferase activity GSTT4; LTC4S; GSTP2; MGST1; GDAP1L1; GSTA2; GSTM4; GSTT2; GDAP1; GSTM7
    kinase regulator activity GSTP1; BCCIP
    nitric oxide binding GSTP1; CBS
    protein binding NME4; F11R; RPS27L; AGPAT1; HBP1; RBFOX1; MYO1C; NAALADL2; FLAD1; CINP

    GSTP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GSTP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of GSTP1.

    TRAF2; KRTAP10-7; KRTAP10-9; KRT31; NOTCH2NL

    Banerjee, J; Mishra, R; et al. A reciprocal role of prostate cancer on stromal DNA damage. ONCOGENE 33:4924-4931(2014).
    Yamamoto, Y; Konishi, H; et al. Significance of GSTP1 for predicting the prognosis and chemotherapeutic efficacy in esophageal squamous cell carcinoma. ONCOLOGY REPORTS 30:1687-1694(2013).

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