gstp1
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  • Official Full Name
  • glutathione S-transferase pi 1
  • Background
  • Glutathione S-transferases (GSTs) are a family of isoenzymes that detoxify electrophiles through conjugation to thiol-reduced glutathione (GSH). Thus, they are critical in protecting cells from toxins (drugs, pesticides, carcinogens) and oxidative stress
  • Synonyms
  • GSTP1; glutathione S-transferase pi 1; FAEES3, GST3; glutathione S-transferase P; GSTP; GSTP1-1; GST class-pi; deafness, X-linked 7; fatty acid ethyl ester synthase III; PI; DFN7; GST3; FAEES3
Cat.#:GSTP1-540MTag:His-SUMO
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse GSTP1 Protein (2-210 aa), His-SUMO-tagged
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Cat.#:GSTP1-4428HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human GSTP1 Protein, GST-tagged
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Cat.#:GSTP1-1086HTag:HIS
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human GSTP1, His-tagged
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Cat.#:GSTP1-250HTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human GSTP1
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Cat.#:Gstp1-29MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Gstp1 protein, His-tagged
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Cat.#:GSTP1-7339MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse GSTP1 Protein
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Cat.#:Gstp1-1493RTag:His
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Gstp1 protein, His-tagged
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Cat.#:GSTP1-580CTag:His
Source (Host):Mammalian CellsSpecies:Cynomolgus Monkey
Product nameRecombinant Cynomolgus GSTP1 Protein, His-tagged
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Cat.#:GSTP1-1997RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey GSTP1 Protein, His-tagged
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Cat.#:GSTP1-9254ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish GSTP1
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Cat.#:GSTP1-1491CTag:His
Source (Host):E. coliSpecies:Cattle
Product nameRecombinant Cattle GSTP1 protein, His-tagged
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Cat.#:GSTP1-5709HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human GSTP1 293 Cell Lysate
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Involved Pathway

GSTP1 involved in several pathways and played different roles in them. We selected most pathways GSTP1 participated on our site, such as Glutathione metabolism, Metabolism of xenobiotics by cytochrome P, Drug metabolism - cytochrome P, which may be useful for your reference. Also, other proteins which involved in the same pathway with GSTP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Glutathione metabolism
SRM; IDH2; GPX4; GGT7; GGT5; GSTT1B; GGCT; RRM2B; GCLC; GSTO1
Metabolism of xenobiotics by cytochrome P
GSTA4; GSTA1; DHDHL; GSTM5; GSTM4; GSTP1; GSTM7; CBR2; MGST1; DHDH
Drug metabolism - cytochrome P
GSTA2; UGT1AB; GSTO1; AOX3; GSTM5; UGT2A1; UGT5G1; GSTP1; UGT1A1; UGT2A2
Pathways in cancer
MMP9; PRKACA; RAD51; BRAF; Flt3l; TRP53; FGF4; TCF7L2; WNT8B; Fasl
Chemical carcinogenesis
CYP2C8; Nat3; PTGS2; FAM84B; UGT1A6A; MGST3; GSTA3; UGT1A6B; GSTM3; CYP2A6
Prostate cancer
ERBB2; CCNE1; PIK3CG; MAP2K1; AKT2; NOXA1; SPINK1; PDGFA; FGFR1; IKBKB

Protein Function

GSTP1 has several biochemical functions, for example, JUN kinase binding, S-nitrosoglutathione binding, dinitrosyl-iron complex binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GSTP1 itself. We selected most functions GSTP1 had, and list some proteins which have the same functions with GSTP1. You can find most of the proteins on our site.
Function
Related Protein
Function JUN kinase binding
Related Protein MAD2L2; SPAG9; PTK2; SPAG9A; GSTP1; MAPK8IP3
Function S-nitrosoglutathione binding
Related Protein GSTP2; GSTP1
Function dinitrosyl-iron complex binding
Related Protein GSTP1; GSTP2
Function glutathione transferase activity
Related Protein GSTM1; GSTO2; LTC4S; GSTM2; GSTA3; GSTM3; GSTP1; MGST3; EEF1G; GSTT2B
Function kinase regulator activity
Related Protein GSTP1; BCCIP
Function nitric oxide binding
Related Protein GSTP1; CBS
Function protein binding
Related Protein HUS1; TFR2; CSN3; NAV2; SP4; ATF6; ITGA2; UTP14A; CHCHD1; CAPN3

Interacting Protein

GSTP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GSTP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of GSTP1.
TRAF2; KRTAP10-7; KRTAP10-9; KRT31; NOTCH2NL

GSTP1 Related Articles

Banerjee, J; Mishra, R; et al. A reciprocal role of prostate cancer on stromal DNA damage. ONCOGENE 33:4924-4931(2014).
Yamamoto, Y; Konishi, H; et al. Significance of GSTP1 for predicting the prognosis and chemotherapeutic efficacy in esophageal squamous cell carcinoma. ONCOLOGY REPORTS 30:1687-1694(2013).