|Official Full Name||glutathione S-transferase pi 1|
|Background||Glutathione S-transferases (GSTs) are a family of isoenzymes that detoxify electrophiles through conjugation to thiol-reduced glutathione (GSH). Thus, they are critical in protecting cells from toxins (drugs, pesticides, carcinogens) and oxidative stress|
|Synonyms||GSTP1; glutathione S-transferase pi 1; FAEES3, GST3; glutathione S-transferase P; GSTP; GSTP1-1; GST class-pi; deafness, X-linked 7; fatty acid ethyl ester synthase III; PI; DFN7; GST3; FAEES3|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
GSTP1 involved in several pathways and played different roles in them. We selected most pathways GSTP1 participated on our site, such as Glutathione metabolism, Metabolism of xenobiotics by cytochrome P, Drug metabolism - cytochrome P, which may be useful for your reference. Also, other proteins which involved in the same pathway with GSTP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Glutathione metabolism||G6PDX; GSTA4; GCLM; LAP3; GSTP1; RRM2; GSTT2B; MGST3; PGD; GSTT1B|
|Metabolism of xenobiotics by cytochrome P||UGT5G1; UGT2A2; GSTM1; GSTT1; UGT1A7; UGT1A2; UGT1A6; GSTA2; UGT1A6A; UGT1AB|
|Drug metabolism - cytochrome P||UGT1A2; MGST3; UGT2A2; GSTA3; UGT1AB; MAOB; FMO6P; ALDH3B2; AOX2P; UGT1A6|
|Pathways in cancer||RALGDS; HHIP; CKS2; STAT5B; PLCG2; FZD3; CTNNA3; RET; PTCH1; PRKCB|
|Chemical carcinogenesis||ALDH3A1; CYP2C54; UGT1A3; MGST3; CYP2C37; UGT1A9; ADH2-2; CYP3A5; AKR1C2; MGST1|
|Prostate cancer||TP53; ARID1A; CCND1; CASP9; IKBKB; RAF1; FGFR1; IKBKG; FOXA1; HSP90AB1|
GSTP1 has several biochemical functions, for example, JUN kinase binding, S-nitrosoglutathione binding, dinitrosyl-iron complex binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GSTP1 itself. We selected most functions GSTP1 had, and list some proteins which have the same functions with GSTP1. You can find most of the proteins on our site.
|JUN kinase binding||MAD2L2; MAPK8IP3; SPAG9; GSTP1; SPAG9A; PTK2|
|S-nitrosoglutathione binding||GSTP1; GSTP2|
|dinitrosyl-iron complex binding||GSTP1; GSTP2|
|glutathione transferase activity||GSTT4; LTC4S; GSTP2; MGST1; GDAP1L1; GSTA2; GSTM4; GSTT2; GDAP1; GSTM7|
|kinase regulator activity||GSTP1; BCCIP|
|nitric oxide binding||GSTP1; CBS|
|protein binding||NME4; F11R; RPS27L; AGPAT1; HBP1; RBFOX1; MYO1C; NAALADL2; FLAD1; CINP|
GSTP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GSTP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of GSTP1.
TRAF2; KRTAP10-7; KRTAP10-9; KRT31; NOTCH2NL