GSTP1
-
Official Full Name
glutathione S-transferase pi 1
-
Overview
Glutathione S-transferases (GSTs) are a family of isoenzymes that detoxify electrophiles through conjugation to thiol-reduced glutathione (GSH). Thus, they are critical in protecting cells from toxins (drugs, pesticides, carcinogens) and oxidative stress -
Synonyms
GSTP1; glutathione S-transferase pi 1; FAEES3, GST3; glutathione S-transferase P; GSTP; GSTP1-1; GST class-pi; deafness, X-linked 7; fatty acid ethyl ester synthase III; PI; DFN7; GST3; FAEES3;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Cattle
- Chinese hamster
- Cynomolgus Monkey
- Hamster
- Human
- Long-tailed dwarf hamster
- Mouse
- Rat
- Rhesus Macaque
- Zebrafish
- E.coli
- HEK293
- HEK293T
- Human
- In Vitro Cell Free System
- Insect Cell
- Mammalian Cell
- Mammalian cells
- Wheat Germ
- Yeast
- Flag
- GST
- His
- HIS
- His (Fc)
- Avi
- Myc
- Strep
- His|SUMO
- DDK
- N/A
- N
- No tag
- Involved Pathway
- Protein Function
- Interacting Protein
- GSTP1 Related Articles
GSTP1 involved in several pathways and played different roles in them. We selected most pathways GSTP1 participated on our site, such as Glutathione metabolism, Metabolism of xenobiotics by cytochrome P, Drug metabolism - cytochrome P, which may be useful for your reference. Also, other proteins which involved in the same pathway with GSTP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
---|---|
Glutathione metabolism | GSTP2;GPX8;GPX1A;GPX2;GPX7;GSTM7;GSTT2;PGD;G6PDX |
Metabolism of xenobiotics by cytochrome P | GSTAL;GSTM;EPHX1;GSTA;DHDH;CBR2;UGT1AB;UGT1A6;SULT2A1 |
Drug metabolism - cytochrome P | GSTM7;GSTP2;UGT1AB;GSTA3;GSTT2;GSTM5;ALDH3B2;AOX4;MGST1.1 |
Pathways in cancer | TCEB1;IL6;PRKCG;FZD10;FAS;FZD2;XIAP;FGF20;PIK3R1 |
Chemical carcinogenesis | ADH1A;CHRNA7;CYP2C50;CYP3A7;ADH2-1;GSTT2;ADH4;MGST2;GSTM5 |
Prostate cancer | PIK3R1;NKX3-1;Pdgfa&Pdgfb;NDRG1;HRAS;NFKB1;SOS1;BRAF;HSP90AA1 |
GSTP1 has several biochemical functions, for example, JUN kinase binding, S-nitrosoglutathione binding, dinitrosyl-iron complex binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GSTP1 itself. We selected most functions GSTP1 had, and list some proteins which have the same functions with GSTP1. You can find most of the proteins on our site.
Function | Related Protein |
---|---|
JUN kinase binding | PTK2;MAD2L2;MAPK8IP3;SPAG9;SPAG9A;GSTP1 |
S-nitrosoglutathione binding | GSTP2;GSTP1 |
dinitrosyl-iron complex binding | GSTP1;GSTP2 |
glutathione transferase activity | GSTZ1;GSTM6;GSTA4;GSTM;GSTT4;MGST1;EEF1E1;GSTAL;GSTM3 |
kinase regulator activity | GSTP1;BCCIP |
nitric oxide binding | CBS;GSTP1 |
protein binding | AP4M1;CLASP1;DAK;HIST2H3C2;ZNRF1;MEPE;PSMB9;NEDD4L;SSSCA1 |
GSTP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GSTP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of GSTP1.
TRAF2; KRTAP10-7; KRTAP10-9; KRT31; NOTCH2NL
- Q&As
- Reviews
Q&As (5)
Ask a questionYes, genetic polymorphisms in GSTP1 can influence an individual's response to certain drugs, impacting their effectiveness and potential side effects.
GSTP1 levels may vary with age, as the enzyme's expression can be influenced by factors such as hormonal changes and environmental exposures.
GSTP1 is frequently studied in prostate cancer, but it is also relevant in breast, lung, and other cancers.
Yes, clinical laboratories can measure GSTP1 expression levels using various molecular techniques, such as PCR and immunohistochemistry.
Future developments may include personalized medicine approaches that consider an individual's GSTP1 genetic profile for optimizing treatment regimens.
Customer Reviews (3)
Write a reviewthe GSTP1 protein is of the highest quality and perfectly suited for your experimental requirements.
The GSTP1 protein is an exceptional choice that meets the highest standards of quality, making it perfectly suited for your experimental needs.
In addition to its exceptional quality, the GSTP1 protein is backed by excellent technical support offered by the manufacturer.
Ask a Question for All GSTP1 Products
Required fields are marked with *
My Review for All GSTP1 Products
Required fields are marked with *