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GSTP1

  • Official Full Name

    glutathione S-transferase pi 1

  • Overview

    Glutathione S-transferases (GSTs) are a family of isoenzymes that detoxify electrophiles through conjugation to thiol-reduced glutathione (GSH). Thus, they are critical in protecting cells from toxins (drugs, pesticides, carcinogens) and oxidative stress
  • Synonyms

    GSTP1; glutathione S-transferase pi 1; FAEES3, GST3; glutathione S-transferase P; GSTP; GSTP1-1; GST class-pi; deafness, X-linked 7; fatty acid ethyl ester synthase III; PI; DFN7; GST3; FAEES3;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Cattle
  • Chinese hamster
  • Cynomolgus Monkey
  • Hamster
  • Human
  • Long-tailed dwarf hamster
  • Mouse
  • Rat
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Human
  • In Vitro Cell Free System
  • Insect Cell
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • Yeast
  • Flag
  • GST
  • His
  • HIS
  • His (Fc)
  • Avi
  • Myc
  • Strep
  • His|SUMO
  • DDK
  • N/A
  • N
  • No tag
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human GSTP1-250H Active Recombinant Human GSTP1 E.coli N/A
Human GSTP1-1086H Active Recombinant Human GSTP1, His-tagged Human HIS
Human GSTP1-4428H Recombinant Human GSTP1 Protein, GST-tagged Wheat Germ GST
Human GSTP1-5709HCL Recombinant Human GSTP1 293 Cell Lysate HEK293 N/A
Human GSTP1-2550H Recombinant Human GSTP1 Protein (2-210 aa), His-tagged Yeast His 2-210 aa
Human GSTP1-3000H Recombinant Human GSTP1 protein, His-tagged E.coli His 2-210aa
Human GSTP1-1215H Recombinant Human GSTP1 protein, GST-tagged E.coli GST 1-210 aa
Human GSTP1-3999H Recombinant Human GSTP1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human GSTP1-3367HF Recombinant Full Length Human GSTP1 Protein, GST-tagged In Vitro Cell Free System GST 210 amino acids
Human GSTP1-3001H Recombinant Human GSTP1 protein, His-tagged E.coli His 2-210aa
Human GSTP1-0313H Recombinant Human GSTP1 Protein (M1-Q210), Tag Free E.coli No tag M1-Q210
Human GSTP1-1032H-B Recombinant Human GSTP1 Protein Pre-coupled Magnetic Beads HEK293
Human GSTP1-0314H Recombinant Human GSTP1 Protein (M1-Q210), His/Strep tagged E.coli His/Strep M1-Q210
Human GSTP1-3002H Recombinant Human GSTP1 protein, GST-tagged E.coli GST 2-210aa
Human GSTP1-3514H Recombinant Human GSTP1 protein, His-tagged E.coli His 1-210 aa
Human GSTP1-1202HFL Recombinant Full Length Human GSTP1 Protein, C-Flag-tagged Mammalian cells Flag
Human GSTP1-1032H Recombinant Human GSTP1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human GSTP1-22H Active Recombinant Human GSTP1 Protein (1-210aa), N-His tagged E.coli N-His 1-210aa
Mouse Gstp1-29M Recombinant Mouse Gstp1 protein, His-tagged E.coli His
Mouse GSTP1-7339M Recombinant Mouse GSTP1 Protein Mammalian Cell His
Mouse GSTP1-1406M Recombinant Mouse GSTP1 Protein (2-210 aa), His-tagged Yeast His 2-210 aa
Mouse GSTP1-540M Recombinant Mouse GSTP1 Protein (2-210 aa), His-SUMO-tagged E.coli His/SUMO 2-210 aa
Mouse GSTP1-3979M-B Recombinant Mouse GSTP1 Protein Pre-coupled Magnetic Beads HEK293
Mouse GSTP1-3979M Recombinant Mouse GSTP1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat Gstp1-1493R Recombinant Rat Gstp1 protein, His-tagged E.coli His Met1~Gln210 (Accession # P04906)
Rat Gstp1-3003R Recombinant Rat Gstp1 protein, His-tagged E.coli His 2-210aa
Cattle GSTP1-1491C Recombinant Cattle GSTP1 protein, His-tagged E.coli His Met1~Gln210 (Accession # P28801)
Chinese hamster GSTP1-2226C Recombinant Chinese hamster GSTP1 protein, His&Myc-tagged Insect Cell His&Myc 1-210aa
Chinese hamster GSTP1-2999C Recombinant Chinese hamster GSTP1 protein, His&Myc-tagged E.coli His&Myc 1-210aa
Cynomolgus Monkey GSTP1-580C Recombinant Cynomolgus GSTP1 Protein, His-tagged Mammalian Cell His
Cynomolgus Monkey GSTP1-326C Recombinant Cynomolgus Monkey GSTP1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Cynomolgus Monkey GSTP1-326C-B Recombinant Cynomolgus Monkey GSTP1 Protein Pre-coupled Magnetic Beads HEK293
Hamster Gstp1-2222H Recombinant Hamster Gstp1 Protein, His-tagged E.coli N-His Met1-Gln210
Long-tailed dwarf hamster GSTP1-5836L Recombinant Long-tailed dwarf hamster GSTP1 protein, His-tagged Yeast His 1-210aa
Rhesus Macaque GSTP1-1997R Recombinant Rhesus monkey GSTP1 Protein, His-tagged Mammalian Cell His
Rhesus Macaque GSTP1-1818R Recombinant Rhesus Macaque GSTP1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque GSTP1-1818R-B Recombinant Rhesus Macaque GSTP1 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish GSTP1-9254Z Recombinant Zebrafish GSTP1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • GSTP1 Related Articles

GSTP1 involved in several pathways and played different roles in them. We selected most pathways GSTP1 participated on our site, such as Glutathione metabolism, Metabolism of xenobiotics by cytochrome P, Drug metabolism - cytochrome P, which may be useful for your reference. Also, other proteins which involved in the same pathway with GSTP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Glutathione metabolismGSTP2;GPX8;GPX1A;GPX2;GPX7;GSTM7;GSTT2;PGD;G6PDX
Metabolism of xenobiotics by cytochrome PGSTAL;GSTM;EPHX1;GSTA;DHDH;CBR2;UGT1AB;UGT1A6;SULT2A1
Drug metabolism - cytochrome PGSTM7;GSTP2;UGT1AB;GSTA3;GSTT2;GSTM5;ALDH3B2;AOX4;MGST1.1
Pathways in cancerTCEB1;IL6;PRKCG;FZD10;FAS;FZD2;XIAP;FGF20;PIK3R1
Chemical carcinogenesisADH1A;CHRNA7;CYP2C50;CYP3A7;ADH2-1;GSTT2;ADH4;MGST2;GSTM5
Prostate cancerPIK3R1;NKX3-1;Pdgfa&Pdgfb;NDRG1;HRAS;NFKB1;SOS1;BRAF;HSP90AA1

GSTP1 has several biochemical functions, for example, JUN kinase binding, S-nitrosoglutathione binding, dinitrosyl-iron complex binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GSTP1 itself. We selected most functions GSTP1 had, and list some proteins which have the same functions with GSTP1. You can find most of the proteins on our site.

Function Related Protein
JUN kinase bindingPTK2;MAD2L2;MAPK8IP3;SPAG9;SPAG9A;GSTP1
S-nitrosoglutathione bindingGSTP2;GSTP1
dinitrosyl-iron complex bindingGSTP1;GSTP2
glutathione transferase activityGSTZ1;GSTM6;GSTA4;GSTM;GSTT4;MGST1;EEF1E1;GSTAL;GSTM3
kinase regulator activityGSTP1;BCCIP
nitric oxide bindingCBS;GSTP1
protein bindingAP4M1;CLASP1;DAK;HIST2H3C2;ZNRF1;MEPE;PSMB9;NEDD4L;SSSCA1

GSTP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GSTP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of GSTP1.

TRAF2; KRTAP10-7; KRTAP10-9; KRT31; NOTCH2NL

Banerjee, J; Mishra, R; et al. A reciprocal role of prostate cancer on stromal DNA damage. ONCOGENE 33:4924-4931(2014).
Yamamoto, Y; Konishi, H; et al. Significance of GSTP1 for predicting the prognosis and chemotherapeutic efficacy in esophageal squamous cell carcinoma. ONCOLOGY REPORTS 30:1687-1694(2013).
  • Q&As
  • Reviews

Q&As (5)

Ask a question
Can GSTP1 genetic variants affect drug metabolism? 11/14/2022

Yes, genetic polymorphisms in GSTP1 can influence an individual's response to certain drugs, impacting their effectiveness and potential side effects.

Can GSTP1 levels change with age? 08/25/2021

GSTP1 levels may vary with age, as the enzyme's expression can be influenced by factors such as hormonal changes and environmental exposures.

In what cancers is GSTP1 commonly studied? 05/25/2020

GSTP1 is frequently studied in prostate cancer, but it is also relevant in breast, lung, and other cancers.

Are there diagnostic tests to assess GSTP1 levels? 11/06/2019

Yes, clinical laboratories can measure GSTP1 expression levels using various molecular techniques, such as PCR and immunohistochemistry.

What are the potential future developments in GSTP1-based clinical applications? 03/09/2017

Future developments may include personalized medicine approaches that consider an individual's GSTP1 genetic profile for optimizing treatment regimens.

Customer Reviews (3)

Write a review
Reviews
11/16/2021

    the GSTP1 protein is of the highest quality and perfectly suited for your experimental requirements.

    07/24/2018

      The GSTP1 protein is an exceptional choice that meets the highest standards of quality, making it perfectly suited for your experimental needs.

      12/01/2016

        In addition to its exceptional quality, the GSTP1 protein is backed by excellent technical support offered by the manufacturer.

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