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HPGD

  • Official Full Name

    hydroxyprostaglandin dehydrogenase 15-(NAD)

  • Overview

    This gene encodes a member of the short-chain nonmetalloenzyme alcohol dehydrogenase protein family. The encoded enzyme is responsible for the metabolism of prostaglandins, which function in a variety of physiologic and cellular processes such as inflammation. Mutations in this gene result in primary autosomal recessive hypertrophic osteoarthropathy and cranioosteoarthropathy. Multiple transcript variants encoding different isoforms have been found for this gene.
  • Synonyms

    HPGD; hydroxyprostaglandin dehydrogenase 15-(NAD); 15-hydroxyprostaglandin dehydrogenase [NAD(+)]; SDR36C1; short chain dehydrogenase/reductase family 36C; member 1; prostaglandin dehydrogenase 1; NAD+-dependent 15-hydroxyprostaglandin dehydrogenase; shor;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Cynomolgus Monkey
  • Human
  • Mouse
  • Rat
  • E. coli
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • C
  • His
  • GST
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • MYC
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human HPGD-13922H Recombinant Human HPGD, GST-tagged E.coli GST 1-266a.a.
Human HPGD-31206TH Recombinant Human HPGD, His-tagged E.coli His 266 amino acids
Human HPGD-5009H Recombinant Human HPGD Protein, GST-tagged Wheat Germ GST
Human HPGD-881H Active Recombinant Human HPGD protein, His-tagged E.coli His Met1-Gln266
Human HPGD-15H Recombinant Human HPGD, His-tagged HEK293 His
Human HPGD-5402HCL Recombinant Human HPGD 293 Cell Lysate HEK293 N/A
Human HPGD-2564H Recombinant Human HPGD Protein (Met1-Gln266), C-His tagged Mammalian cells C-His Met1-Gln266
Human HPGD-5147H Recombinant Human HPGD Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human HPGD-43H Recombinant Human HPGD Protein, GST-tagged E.coli GST 1-266
Human HPGD-063H Recombinant Human HPGD Protein, GST-tagged E. coli GST 1-266
Human HPGD-3624HF Recombinant Full Length Human HPGD Protein, GST-tagged In Vitro Cell Free System GST 266 amino acids
Mouse Hpgd-2525M Active Recombinant Mouse Hpgd protein, His-tagged E.coli His Met 1-Ser 269
Mouse HPGD-7829M Recombinant Mouse HPGD Protein Mammalian Cell His
Mouse Hpgd-1164M Recombinant Mouse Hpgd Protein, MYC/DDK-tagged HEK293T MYC/DDK
Mouse HPGD-4306M Recombinant Mouse HPGD Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse HPGD-4306M-B Recombinant Mouse HPGD Protein Pre-coupled Magnetic Beads HEK293
Rat HPGD-2902R Recombinant Rat HPGD Protein Mammalian Cell His
Rat HPGD-2557R Recombinant Rat HPGD Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat HPGD-2557R-B Recombinant Rat HPGD Protein Pre-coupled Magnetic Beads HEK293
Cynomolgus Monkey HPGD-594C Recombinant Cynomolgus HPGD Protein, His-tagged Mammalian Cell His
Cynomolgus Monkey HPGD-340C-B Recombinant Cynomolgus Monkey HPGD Protein Pre-coupled Magnetic Beads HEK293
Cynomolgus Monkey HPGD-340C Recombinant Cynomolgus Monkey HPGD Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Chicken HPGD-5143C Recombinant Chicken HPGD Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • HPGD Related Research Area

HPGD involved in several pathways and played different roles in them. We selected most pathways HPGD participated on our site, such as Transcriptional misregulation in cancer, which may be useful for your reference. Also, other proteins which involved in the same pathway with HPGD were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Transcriptional misregulation in cancerCD40;Itgam&Itgb2;MAX;MMP9;HIST2H3A;MDM2;RXRB;ETV1;LYL1

HPGD has several biochemical functions, for example, 15-hydroxyprostaglandin dehydrogenase (NAD+) activity, NAD binding, NAD+ binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HPGD itself. We selected most functions HPGD had, and list some proteins which have the same functions with HPGD. You can find most of the proteins on our site.

Function Related Protein
15-hydroxyprostaglandin dehydrogenase (NAD+) activity
NAD bindingDLD;CTBP2L;AOX3L1;LDHA;HADHA;CTBP2A;TESCA;ADH4;LDHB
NAD+ bindingUXS1;SIRT3;SIRT7;HADH;SIRT6;SIRT5;GLUD1;ALDH1A3;SIRT4
catalytic activityECI2;SYN3;FHIT;CKMT2B;ALPI.1;SYN1;CPS1;Amy1;SYN2B
prostaglandin E receptor activityPTGER1B;PTGER4C;PTGER2A;PTGER1C;PTGER1;HPGD;PTGER1A;PTGER4B;PTGER2B
protein homodimerization activitySPATA24;GRM6;TESC;NOS1;CHUK;CRYM;GZMA;PYGL;CECR1

HPGD has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HPGD here. Most of them are supplied by our site. Hope this information will be useful for your research of HPGD.

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