HPGD

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HPGD

Official Full Name hydroxyprostaglandin dehydrogenase 15-(NAD)
Background This gene encodes a member of the short-chain nonmetalloenzyme alcohol dehydrogenase protein family. The encoded enzyme is responsible for the metabolism of prostaglandins, which function in a variety of physiologic and cellular processes such as inflammation. Mutations in this gene result in primary autosomal recessive hypertrophic osteoarthropathy and cranioosteoarthropathy. Multiple transcript variants encoding different isoforms have been found for this gene.
Synonyms HPGD; hydroxyprostaglandin dehydrogenase 15-(NAD); 15-hydroxyprostaglandin dehydrogenase [NAD(+)]; SDR36C1; short chain dehydrogenase/reductase family 36C; member 1; prostaglandin dehydrogenase 1; NAD+-dependent 15-hydroxyprostaglandin dehydrogenase; shor
    • Species :
    • Chicken
    • Cynomolgus Monkey
    • Human
    • Mouse
    • Rat
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Mouse Hpgd-1164M Recombinant Mouse Hpgd Protein, MYC/DDK-tagged HEK293T MYC/DDK
    Human HPGD-43H Recombinant Human HPGD Protein, GST-tagged E.coli GST
    Human HPGD-5147H Recombinant Human HPGD Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human HPGD-13922H Recombinant Human HPGD, GST-tagged E.coli GST
    Human HPGD-15H Recombinant Human HPGD, His-tagged HEK293 His
    Human HPGD-31206TH Recombinant Human HPGD, His-tagged E.coli His
    Human HPGD-5009H Recombinant Human HPGD Protein, GST-tagged Wheat Germ GST
    Human HPGD-5402HCL Recombinant Human HPGD 293 Cell Lysate HEK293 N/A
    Human HPGD-881H Recombinant Human HPGD, His tagged E.coli His
    Mouse Hpgd-2525M Recombinant Mouse Hpgd protein, His-tagged E.coli His
    Mouse HPGD-7829M Recombinant Mouse HPGD Protein Mammalian Cell His
    Rat HPGD-2902R Recombinant Rat HPGD Protein Mammalian Cell His
    Cynomolgus Monkey HPGD-594C Recombinant Cynomolgus HPGD Protein, His-tagged Mammalian Cell His
    Chicken HPGD-5143C Recombinant Chicken HPGD Mammalian Cell His

    HPGD involved in several pathways and played different roles in them. We selected most pathways HPGD participated on our site, such as Transcriptional misregulation in cancer, which may be useful for your reference. Also, other proteins which involved in the same pathway with HPGD were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Transcriptional misregulation in cancer ETV1; HHEX; GOLPH3; FUT8; ATM; TFE3; ELK4; SPI1; RUNX1T1; LRP2BP

    HPGD has several biochemical functions, for example, 15-hydroxyprostaglandin dehydrogenase (NAD+) activity, NAD binding, NAD+ binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HPGD itself. We selected most functions HPGD had, and list some proteins which have the same functions with HPGD. You can find most of the proteins on our site.

    Function Related Protein
    15-hydroxyprostaglandin dehydrogenase (NAD+) activity HPGD
    NAD binding IDH2; ME1; CTBP2L; GRHPRA; GAPDH; CYB5R3; GLYR1; CTBP2A; GPD1L; HADHA
    NAD+ binding HADH; SIRT6; SIRT7; GLUD1; SIRT4; SIRT3; SIRT1; HPGD; SIRT5; UXS1
    catalytic activity ALPI.2; ACLYA; GMPR2; TM9SF1; PFKFB2A; PIGH; LANCL1; ALDOAA; MOXD2; HADHAA
    prostaglandin E receptor activity PTGER1; PTGER2; PTGER2B; HPGD; PTGER4B; PTGER1B; PTGER1A; PTGER2A; PTGER4C; PTGER4A
    protein homodimerization activity BCL2A1A; BAXA; PLD6; ID1; IMPA2; NR0B2; MUC13; TARBP2; EIF2AK1; SUPV3L1

    HPGD has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HPGD here. Most of them are supplied by our site. Hope this information will be useful for your research of HPGD.

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