Recombinant Human HPGD Protein, GST-tagged HPGD-43H

Recombinant Human HPGD Protein, GST-tagged


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Recombinant Human HPGD Protein, GST-tagged

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Cat.No. : HPGD-43H
Product Overview : Recombinant human HPGD(1-266) protein with a N-terminal GST-tag was expressed in E. coli.
Description : This gene encodes a member of the short-chain nonmetalloenzyme alcohol dehydrogenase protein family. The encoded enzyme is responsible for the metabolism of prostaglandins, which function in a variety of physiologic and cellular processes such as inflammation. Mutations in this gene result in primary autosomal recessive hypertrophic osteoarthropathy and cranioosteoarthropathy. Multiple transcript variants encoding different isoforms have been found for this gene.
Source : E. coli
Species : Human
Tag : GST
Molecular Mass : 55 kDa
Protein length : 1-266
Purity : ≥90% estimated by SDS-PAGE
Unit Definition : One unit is defined as the amount of enzyme required to produce 1 nmol of NADH per minute at 37 centigrade in 50 mM Tris-HCl, pH 7.5, 0.1 mM DTT, 50 μM PGE2, and 1 mM NAD+.
Stability : ≥ 6 months
Storage : Store it at -80 centigrade
Storage Buffer : 50 mM Tris-HCl, pH 7.5, containing 1 mM EDTA, 1 mM DTT, and 30% glycerol
SDS-PAGE Analysis of HPGD :

Lane 1: MW Markers; Lane 2: 15-hydroxy PGDH (2 μg); Lane 3: 15-hydroxy PGDH (4 μg). Representative gel image shown; actual purity may vary between each batch.

Gene Name : HPGD 15-hydroxyprostaglandin dehydrogenase [ Homo sapiens (human) ]
Official Symbol : HPGD
Synonyms : HPGD; 15-hydroxyprostaglandin dehydrogenase; PGDH; PGDH1; PHOAR1; 15-PGDH; SDR36C1; 15-hydroxyprostaglandin dehydrogenase [NAD(+)]; 15-hydroxyprostaglandin dehydrogenase (NAD(+)); NAD+-dependent 15-hydroxyprostaglandin dehydrogenase; hydroxyprostaglandin dehydrogenase 15-(NAD); prostaglandin dehydrogenase 1; short chain dehydrogenase/reductase family 36C member 1
Gene ID : 3248
mRNA Refseq : NM_000860
Protein Refseq : NP_000851
MIM : 601688
UniProt ID : P15428

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