il11ra
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  • Official Full Name
  • interleukin 11 receptor, alpha
  • Background
  • Interleukin 11 is a stromal cell-derived cytokine that belongs to a family of pleiotropic and redundant cytokines that use the gp130 transducing subunit in their high affinity receptors. This gene encodes the IL-11 receptor, which is a member of the hematopoietic cytokine receptor family. This particular receptor is very similar to ciliary neurotrophic factor, since both contain an extracellular region with a 2-domain structure composed of an immunoglobulin-like domain and a cytokine receptor-like domain. Alternative splicing has been observed at this locus, and three variants encoding two different isoforms have been identified.
  • Synonyms
  • IL11RA; interleukin 11 receptor, alpha; interleukin-11 receptor subunit alpha; hCG_2011440; I11RA_HUMAN; IL-11 receptor subunit alpha; IL-11R subunit alpha; IL-11R-alpha; IL-11RA; Interleukin 11 receptor alpha; MGC2146; OTTHUMP00000021300; OTTHUMP00000021301; OTTHUMP00000244525; OTTHUMP00000244527; OTTHUMP00000244532; interleukin-11 receptor alpha chain; CRSDA
Cat.#:IL11RA-1328HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human IL11RA protein, His-tagged
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Cat.#:IL11RA-3155HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human IL11RA, His tagged
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Cat.#:IL11RA-1046CTag:Fc
Source (Host):HEK293Species:Canine
Product nameRecombinant Canine IL11RA Protein, Fc-tagged
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Cat.#:IL11RA-173CTag:His
Source (Host):HEK293Species:Canine
Product nameRecombinant Canine IL11RA, His-tagged
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Cat.#:IL11RA-174CTag:His
Source (Host):HEK293Species:Canine
Product nameRecombinant Canine IL11RA, LEVLFQ tagged
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Cat.#:IL11RA-3466CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken IL11RA
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Cat.#:IL11RA-6298ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish IL11RA
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Cat.#:IL11RA-2389HCLTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human IL11RA cell lysate
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Cat.#:IL11RA-2558MCLTag:
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse IL11RA cell lysate
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Cat.#:IL11RA-001CCLTag:
Source (Host):HEK293Species:Canine
Product nameRecombinant Canine IL11RA cell lysate
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Involved Pathway

IL11RA involved in several pathways and played different roles in them. We selected most pathways IL11RA participated on our site, such as Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Hematopoietic cell lineage, which may be useful for your reference. Also, other proteins which involved in the same pathway with IL11RA were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cytokine-cytokine receptor interaction
IFNA12; KITLGA; TNFSF12; IL13RA1; VEGFA; TNFRSF11A; ACVR2B; CCL20B; CCR7; Pdgfa&Pdgfb
Jak-STAT signaling pathway
IL28A; PRL; SOCS9; IL4; SOCS5B; PIAS4A; PIK3CA; PIAS2; IL3RA; IL12BA
Hematopoietic cell lineage
Cd24a; FLT3LG; GYPA; Kitl; IL2RA; FCGR1A; Itgam&Itgb2; IL6R; ITGA3; IL5

Protein Function

IL11RA has several biochemical functions, for example, cytokine receptor activity, signal transducer activity, transmembrane signaling receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by IL11RA itself. We selected most functions IL11RA had, and list some proteins which have the same functions with IL11RA. You can find most of the proteins on our site.
Function
Related Protein
Function cytokine receptor activity
Related Protein IL2RGA; LIFRB; LIFRA; F3A; IL13RA1; F3B; IL20RB; IL12B; IL12RB1; GHRA
Function signal transducer activity
Related Protein MIER1B; S1PR5A; TAS2R202; ECT2; GNAQ; CXCR4B; OLFR502; TAS2R137; PLCG2; COPS2
Function transmembrane signaling receptor activity
Related Protein TLR7; OR4D6; CD300C; GHRHR2; OR6K3; CELSR3; P2RX6; CLDN4; GPR133; NRXN3

IL11RA Related Gene Family

IL