il29
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  • Official Full Name
  • interleukin 29 (interferon, lambda 1)
  • Background
  • This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28A (IL28A), and interleukin 28B (IL28B) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA).
  • Synonyms
  • IL29; interleukin 29 (interferon, lambda 1); interleukin 29; interleukin-29; IFNL1; IL 29; IFN-lambda-1; cytokine Zcyto21; interferon lambda-1; interferon-lambda-1; interferon, lambda 1; IL-29
Cat.#:IL29-5200HTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human IL29 Protein
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Cat.#:IL29-001HTag:Fc
Source (Host):CHOSpecies:Human
Product nameRecombinant Human IL29, MIgG2a Fc-tagged
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Cat.#:IL29-002HTag:Fc
Source (Host):CHOSpecies:Human
Product nameRecombinant Human IL29, HIgG1 Fc-tagged, mutant
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Cat.#:IL29-003HTag:Fc
Source (Host):CHOSpecies:Human
Product nameRecombinant Human IL29, HIgG1 Fc-tagged
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Cat.#:IL29-14194HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human IL29, His-tagged
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Cat.#:IL29-381HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human IL29, His tagged
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Cat.#:IL29-602HTag:N/A
Source (Host):HEK293Species:Human
Product nameRecombinant Human Interleukin 29 (interferon, lambda 1)
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Cat.#:IL29-100HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Interleukin 29 (Interferon, Lambda 1)
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Cat.#:IL29-222HTag:His
Source (Host):NS0Species:Human
Product nameRecombinant Human Interleukin 29 (Interferon, Lambda 1), His-tagged
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Cat.#:IL29-5228HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human IL29 293 Cell Lysate
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Cat.#:IL29-37HTag:
Source (Host):Species:Human
Product nameInterleukin-29 (Interferon Lamda 1) Reference standard
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Involved Pathway

IL29 involved in several pathways and played different roles in them. We selected most pathways IL29 participated on our site, such as Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with IL29 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cytokine-cytokine receptor interaction
Kitl; IFNAR1; IL1RAP; VEGFB; GHRA; Ccl9; CXCL2; IL12RB1; KITLG; TNF
Jak-STAT signaling pathway
IFNA14; IL23; IFNA4; SOCS6; IL4R; OSM; IL2RA; SOCS4; IFNA12; PTPN11

Protein Function

IL29 has several biochemical functions, for example, cytokine activity, interleukin-28 receptor binding, receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IL29 itself. We selected most functions IL29 had, and list some proteins which have the same functions with IL29. You can find most of the proteins on our site.
Function
Related Protein
Function cytokine activity
Related Protein BMP1; TNFSF10; TNFSF13; CMTM1; IFNG1-2; IL17F; KITLG; IL29; IL11; GRN
Function interleukin-28 receptor binding
Related Protein IL29
Function receptor binding
Related Protein MBL2; SELPLG; ANGPTL2; FGG; FGF12B; PPY; FGF6B; UFD1L; CADM2A; LBP

IL29 Related Articles

Ghoneum, M; Agrawal, S; et al. MGN-3/BIOBRAN ENHANCES GENERATION OF CYTOTOXIC CD8+T CELLS VIA UPREGULATION OF DEC-205 EXPRESSION ON DENDRITIC CELLS. INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY 27:523-530(2014).
Zhang, LL; Jilg, N; et al. IL28B inhibits hepatitis C virus replication through the JAK-STAT pathway. JOURNAL OF HEPATOLOGY 55:289-298(2011).
WILLIAMS, RC; MALONE, CC; et al. IGG ANTI-F(AB')(2) ANTIBODIES FROM SLE PATIENTS REACT WITH IMMUNODOMINANT RESIDUES IN KAPPA-CDRS, BUT SHOW REDUCED C-KAPPA REGION REACTIVITY. CLINICAL IMMUNOLOGY AND IMMUNOPATHOLOGY 77:366-373(1995).