Recombinant Human IL29 Protein

• Cat.No.: IL29-513H
• Product Overview: Recombinant human IL29 protein

Specification

• Description: This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28A (IL28A), and interleukin 28B (IL28B) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA).
• Species: Human
• Form: Lyophilized
• Protein length: 200
• AA Sequence: MAAAWTVVLVTLVLGLAVAGPVPTS KPTTTGKGCHIGRFKSLSPQELASF KKARDALEESLKLKNWSCSSPVFPG NWDLRLLQVRERPVALEAELALTLK VLEAAAGPALEDVLDQPLHTLHHIL SQLQACIQPQPTAGPRPRGRLHHWL HRLQEAPKKESAGCLEASVTFNLFR LLTRDLKYVADGNLCLRTSTHPEST
• Purity: > 98%
• Applications: WB; ELISA; FACS; FC
• Stability: This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use.
• Storage: At -20 centigrade.
• Storage Buffer: PBS (pH 7.4-7.5). Sterile-filtered colorless solution.
• Reconstitution: Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance.

Gene Information

• Gene Name: IL29 interleukin 29 (interferon, lambda 1) [ Homo sapiens (human) ]
• Official Symbol: IL29
• Synonyms: IL29; interleukin 29 (interferon, lambda 1); interleukin 29; interleukin-29; IFNL1; IL 29; IFN-lambda-1; cytokine Zcyto21; interferon lambda-1; interferon-lambda-1; interferon, lambda 1; IL-29
• Gene ID: 282618
• mRNA Refseq: NM_172140
• Protein Refseq: NP_742152
• MIM: 607403
• UniProt ID: Q8IU54

Reviews

10/12/2022

Storage conditions are very simple and can be stored for a long time.

04/30/2022

Anti-pollution ability is very strong, not easy to be polluted.

09/12/2019

Labeling effect is very good, can be fluorescent labeling and so on.

Q&As

How should the dose of IL29 be determined?

The dose of IL29 should be determined according to the specific disease and patient situation, and the most appropriate dose usually needs to be determined through clinical trials and individualized treatment.

What is the difference between IL29 and IL28?

IL29 and IL28 are two similar interferons that are similar in structure and function, but with some minor differences such as receptor affinity and signaling pathways.

What are the advantages of IL29 compared with traditional drugs?

IL29 is highly targeted and safe, and can stimulate the response of the own immune system, which has better therapeutic effect and fewer side effects than traditional drugs.

Does IL29 have antioxidant effects?

At present, there are no clear studies to prove that IL29 has a direct antioxidant effect, but it may indirectly affect oxidative stress response by regulating immune system function.

Recombinant IL29 has potential in the treatment of which autoimmune diseases?

IL29 has potential in the treatment of rheumatoid arthritis, hepatitis B, psoriasis and other autoimmune diseases.

Are there side effects of IL29?

It may cause some mild side effects, such as fever, fatigue, headache, etc., but it is generally reversible, and serious side effects are rare.