Recombinant Human Interleukin 29 (Interferon, Lambda 1), His-tagged
Cat.No. : | IL29-222H |
Product Overview : | Recombinant Human interleukin 29 DNA sequence encoding the signal peptide from human CD33 was fused to the carboxylterminally his-tagged mature human IL-29 (Gly 20 - Thr 200). The chimeric protein was expressed in a mouseNSO Cells. |
- Specification
- Gene Information
- Related Products
Cat. No. : | IL29-222H |
Description : | Interleukin-29 (IL-29), also known as IFN-lambda1, is a protein of the helical cytokine family and is a type III interferon. It is also known as IFNλ1 and is highly similar in amino acid sequence to the IL-28, the other type III interferon. IL-29 stimulates antiviral responses through a heterodimeric receptor. It plays an important role in host defenses against microbes and its gene is highly upregulated in cells infected with viruses. |
Source : | Mammalian cells |
Molecular Weight : | The predicted molecular weight of Recombinant Human IL-29 is Mr 21.4 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 26-35 kDa. |
State Of Matter : | Lyophilized. |
Formulation : | This recombinant protein was 0.2 µm filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 – 7.3 with no calcium, magnesium, or preservatives. |
Purity : | > 95% by SDS Page and analyzed by silver stain. |
Endotoxin : | < 1.0 EU/µg as determined by the LAL method. |
Biological Activity : | The biological activity of Human IFN-Lambda1 was determined in an anti-viral assay using human HepG2 cells infected with encephalomyocarditis. The expected ED50 for this effect is typically 1 - 5 ng/mL. |
Storage And Stability : | This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions. |
Gene Name : | IL29 interleukin 29 (interferon, lambda 1) [ Homo sapiens ] |
Synonyms : | IL29; IL-29; IFNL1; IL-28A; IL-28B; IFN-lambda-1; ZCYTO21; interferon-λ2 (IFN-λ2); IFN-λ3; and IFN-λ1; Cytokine ZCYTO21; Interferon lambda-1; interferon, lambda 1; interleukin 29; interleukin 29 (interferon, lambda 1) |
Gene ID : | 282618 |
mRNA Refseq : | NM_172140 |
Protein Refseq : | NP_742152 |
UniProt ID : | Q8IU54 |
Chromosome Location : | 19q13.13 |
MIM : | 607403 |
Pathway : | Cytokine-cytokine receptor interaction; Jak-STAT signaling pathway |
Function : | cytokine activity; interleukin-28 receptor binding |
Products Types
◆ Recombinant Protein | ||
IL29-2309H | Recombinant Human IL29 Protein, His-tagged | +Inquiry |
IL29-3152H | Recombinant Human IL29 Protein, His (Fc)-Avi-tagged | +Inquiry |
IL29-5200H | Active Recombinant Human IL29 Protein | +Inquiry |
IL29-34H | Active Recombinant Human IL29 Protein, Animal Free | +Inquiry |
IL29-513H | Recombinant Human IL29 Protein | +Inquiry |
◆ Lysates | ||
IL29-5228HCL | Recombinant Human IL29 293 Cell Lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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