Active Recombinant Human IL29 Protein

Cat.No. : IL29-5200H
Product Overview : Human IL29 (Q8IU54 , 24 a.a. - 200 a.a.) partial recombinant protein expressed in Escherichia coli.
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  • Gene Information
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Description : This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28A (IL28A), and interleukin 28B (IL28B) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA). [provided by RefSeq
Source : E. coli
Species : Human
Form : Lyophilized
Bio-activity : The ED50 is determined in an anti-viral assay using human HepG2 cells infected with EMCV is typically 1-5 ng/mL.
Molecular Mass : 20 kDa
AA Sequence : TSKPTTTGKGCHIGRFKSLSPQELA SFKKARDALEESLKLKNWSCSSPVF PGNWDLRLLQVRERPVALEAELALT LKVLEAAAGPALEDVLDQPLHTLHH ILSQLQACIQPQPTAGPRPRGRLHH WLHRLQEAPKKESAGCLEASVTFNL FRLLTRDLKYVADGNLCLRTSTHPE ST
Endotoxin : < 0.1 ng/μg (1 EU/μg)
Purity : > 90% by SDS-PAGE and HPLC
Applications : Functional Study
SDS-PAGE
Storage : Store at -20 centigrade on dry atmosphere for 2 years. After reconstitution with deionized water, store at 4 centigrade for 1 month or store at -20 centigrade for 6 months. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : Lyophilized from 20 mM PB, 130 mM NaCl, pH 7.5
Gene Name : IL29 interleukin 29 (interferon, lambda 1) [ Homo sapiens ]
Official Symbol : IL29
Synonyms : IL29; interleukin 29 (interferon, lambda 1); interleukin 29; interleukin-29; IFNL1; IL 29; IFN-lambda-1; cytokine Zcyto21; interferon lambda-1; interferon-lambda-1; interferon, lambda 1; IL-29;
Gene ID : 282618
mRNA Refseq : NM_172140
Protein Refseq : NP_742152
MIM : 607403
UniProt ID : Q8IU54

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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How should the dose of IL29 be determined? 08/01/2022

The dose of IL29 should be determined according to the specific disease and patient situation, and the most appropriate dose usually needs to be determined through clinical trials and individualized treatment.

What is the difference between IL29 and IL28? 06/02/2021

IL29 and IL28 are two similar interferons that are similar in structure and function, but with some minor differences such as receptor affinity and signaling pathways.

What are the advantages of IL29 compared with traditional drugs? 03/22/2021

IL29 is highly targeted and safe, and can stimulate the response of the own immune system, which has better therapeutic effect and fewer side effects than traditional drugs.

Does IL29 have antioxidant effects? 01/11/2021

At present, there are no clear studies to prove that IL29 has a direct antioxidant effect, but it may indirectly affect oxidative stress response by regulating immune system function.

Recombinant IL29 has potential in the treatment of which autoimmune diseases? 07/06/2020

IL29 has potential in the treatment of rheumatoid arthritis, hepatitis B, psoriasis and other autoimmune diseases.

Are there side effects of IL29? 04/18/2020

It may cause some mild side effects, such as fever, fatigue, headache, etc., but it is generally reversible, and serious side effects are rare.

Customer Reviews (3)

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Reviews
10/12/2022

    Detect whether recombinant IL-29 protein causes immune responses, including allergic reactions, to avoid potential safety concerns. -

    04/30/2022

      The biological activity of recombinant IL-29 protein was verified by cell experiments, including its effects on target cells, such as inhibiting viral proliferation and enhancing immune response. At the same time, to understand its interaction with relevant signaling pathways, to further evaluate its efficacy. -

      09/12/2019

        It has the function of inhibiting virus proliferation and enhancing immune response. -

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