Active Recombinant Human IL29 Protein (Pro23-Thr200), C-His tagged, Animal-free, Carrier-free

• Cat.No.: IL29-131H
• Product Overview: Recombinant Human IL29 Protein (Pro23-Thr200) with C-His tag was expressed in E. coli and Animal-free as well as Carrier-free.

Specification

• Description: Interleukin 29 (IL-29) is a cytokine, predicts a molecular mass of 21.9 kDa. It belongs to type III interferons group, also termed interferons λ (IFN-λ). Its induction of STAT3-STAT5 has also been displayed, albeit to a lesser degree. The STAT1 /STAT2 signaling cascade transpires as follows: once tyrosine residues on STAT1 and STAT2 are phosphorylated, these proteins dimerize and are subsequently transported to the nucleus.
• Source: E. coli
• Species: Human
• Tag: C-His
• Form: Lyophilized
• Bio-activity: Measure by its ability to induce IL-8 secretion in HuH7 cells. The ED50 for this effect is < 6 ng/mL.
• Molecular Mass: The protein has a calculated MW of 20.70 kDa.
  The protein migrates as 22 kDa under reducing condition (SDS-PAGE analysis).
• Protein Length: Pro23-Thr200
• Endotoxin: < 0.1 EU/μg of the protein by the LAL method.
• Purity: >98% as determined by SDS-PAGE analysis.
• Storage: This product is stable after storage at:
  -20 centigrade for 12 months in lyophilized state from date of receipt.
  -20 or -80 centigrade for 1 month under sterile conditions after reconstitution.
  Avoid repeated freeze/thaw cycles.
• Storage Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 8.0.
• Reconstitution: It is recommended to reconstitute the lyophilized protein in sterile H2O to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.
• Shipping: The product is shipped with polar packs. Upon receipt, store it immediately at -20 centigrade or lower for long term storage.

Gene Information

• Gene Name: IL29 interleukin 29 (interferon, lambda 1) [ Homo sapiens (human) ]
• Official Symbol: IL29
• Synonyms: IL29; interleukin 29 (interferon, lambda 1); interleukin 29; interleukin-29; IFNL1; IL 29; IFN-lambda-1; cytokine Zcyto21; interferon lambda-1; interferon-lambda-1; interferon, lambda 1; IL-29
• Gene ID: 282618
• mRNA Refseq: NM_172140
• Protein Refseq: NP_742152
• MIM: 607403
• UniProt ID: Q8IU54