mpz
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  • Official Full Name
  • myelin protein zero
  • Background
  • This gene encodes a major structural protein of peripheral myelin. Mutations in this gene result in the autosomal dominant form of Charcot-Marie-Tooth disease type 1 and other polyneuropathies. [provided by RefSeq, Apr 2010]
  • Synonyms
  • MPZ; myelin protein zero; P0; CHM; DSS; MPP; CMT1; CMT1B; CMT2I; CMT2J; CMT4E; CMTDI3; CMTDID; HMSNIB; myelin protein P0; myelin peripheral protein; Charcot-Marie-Tooth neuropathy 1B;
Cat.#:MPZ-1218HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human MPZ Protein (30-156 aa), GST-tagged
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Cat.#:MPZ-1461HTag:His
Source (Host):YeastSpecies:Human
Product nameRecombinant Human MPZ Protein (30-156 aa), His-tagged
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Cat.#:MPZ-5524HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human MPZ Protein, GST-tagged
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Cat.#:MPZ-2294HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human MPZ protein, His-tagged
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Cat.#:MPZ-29152THTag:
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human MPZ
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Cat.#:MPZ-3902HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human MPZ protein, MYC/DDK-tagged
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Cat.#:MPZ-8493HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human MPZ protein, His-tagged
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Cat.#:MPZ-3744RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat MPZ Protein
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Cat.#:MPZ-9712ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish MPZ
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Cat.#:MPZ-4219HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human MPZ 293 Cell Lysate
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Involved Pathway

MPZ involved in several pathways and played different roles in them. We selected most pathways MPZ participated on our site, such as Cell adhesion molecules (CAMs), which may be useful for your reference. Also, other proteins which involved in the same pathway with MPZ were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cell adhesion molecules (CAMs)
SELE; CLDN7; NRXN2; CLDND; NEO1; MADCAM1; HLA-C; F11R.1; NLGN2; HLA-DRB1

Protein Function

MPZ has several biochemical functions, for example, structural molecule activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MPZ itself. We selected most functions MPZ had, and list some proteins which have the same functions with MPZ. You can find most of the proteins on our site.
Function
Related Protein
Function structural molecule activity
Related Protein KRT38; KRT18; SPRR1B; ROCK2; KRT73; MAP7; JAG1; CLDN20; SNTB1; CYT1L

Interacting Protein

MPZ has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MPZ here. Most of them are supplied by our site. Hope this information will be useful for your research of MPZ.
CCP110; PSMB3; PINX1

MPZ Related Articles

Yamaguchi, Y; Hayashi, A; et al. L-MPZ, a Novel Isoform of Myelin P0, Is Produced by Stop Codon Readthrough. JOURNAL OF BIOLOGICAL CHEMISTRY 287:17765-17776(2012).
Bai, Q; Sun, M; et al. Major Isoform of Zebrafish P0 Is a 23.5 KDa Myelin Glycoprotein Expressed in Selected White Matter Tracts of the Central Nervous System. JOURNAL OF COMPARATIVE NEUROLOGY 519:1580-1596(2011).