Mettl3

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Mettl3

Official Full Name methyltransferase-like 3
    • Species :
    • Human
    • Mouse
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Insect Cell
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • Myc/DDK
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human METTL3-12H Recombinant Human METTL3 Protein, His-tagged Insect Cell His
    Human METTL3-1630H Recombinant Human METTL3 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Mouse Mettl3-4048M Recombinant Mouse Mettl3 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Human METTL3-1082HCL Recombinant Human METTL3 cell lysate N/A
    Human METTL3-836H Recombinant Human METTL3, His-tagged E.coli His
    Human METTL3-837H Recombinant Human METTL3 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human METTL3-838H Recombinant Human METTL3 Protein, GST-tagged Wheat Germ GST
    Mouse METTL3-9761M Recombinant Mouse METTL3 Protein Mammalian Cell His
    Zebrafish METTL3-12048Z Recombinant Zebrafish METTL3 Mammalian Cell His

    Mettl3 involved in several pathways and played different roles in them. We selected most pathways Mettl3 participated on our site, such as Gene Expression, Processing of Capped Intron-Containing Pre-mRNA, mRNA processing, which may be useful for your reference. Also, other proteins which involved in the same pathway with Mettl3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Gene Expression TSNAX; PUS1; ZFP473; FAM98B; APOBEC1; JARID2; ZNF559; WTAP; POU2F1B; ZNF221
    Processing of Capped Intron-Containing Pre-mRNA HNRNPUL1; PTBP1B; NUDT21; DNAJC8; CSTF1; RNPC3; CCAR1; HNRNPH2; CLP1; RNPS1
    mRNA processing PRPF4BB; NONO; PTBP1; CELF2; DDX39; FAM120B; RBM39; ZFP740; RBM33; RAVER1

    Mettl3 has several biochemical functions, for example, RNA binding, RNA methyltransferase activity, mRNA (2-O-methyladenosine-N6-)-methyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Mettl3 itself. We selected most functions Mettl3 had, and list some proteins which have the same functions with Mettl3. You can find most of the proteins on our site.

    Function Related Protein
    RNA binding CAPRIN2; PUSL1; CSTF1; U2AF1L4; SURF6; IMPDH2; CDKN2AIP; IFIT8; CNOT7; PCBP3
    RNA methyltransferase activity METTL23; FAM86; PRDM12; PRMT8B; METTL7B; PRDM11; METTL8; FBLL1; DIMT1; RNMTL1B
    mRNA (2-O-methyladenosine-N6-)-methyltransferase activity METTL3; METTL14

    Mettl3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Mettl3 here. Most of them are supplied by our site. Hope this information will be useful for your research of Mettl3.

    MYC; ACTR2; MPP1; WTAP; RBM15B; PPHLN1; METTL14; ROBO2; SEL1L

    Geula, S; Moshitch-Moshkovitz, S; et al. m(6)A mRNA methylation facilitates resolution of naive pluripotency toward differentiation. SCIENCE 347:1002-1006(2015).
    Yang, Y; Sun, BF; et al. Dynamic m(6)A modification and its emerging regulatory role in mRNA splicing. SCIENCE BULLETIN 60:21-32(2015).

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