Recombinant Human METTL3 Protein (Gln357-Leu580), N-His tagged

• Cat.No.: METTL3-3781H
• Product Overview: Recombinant human METTL3 (Gln357-Leu580) fused with the N-His tag was expressed in E. coli.

Specification

• Description: This gene encodes the 70 kDa subunit of MT-A which is part of N6-adenosine-methyltransferase. This enzyme is involved in the posttranscriptional methylation of internal adenosine residues in eukaryotic mRNAs, forming N6-methyladenosine.
• Source: E. coli
• Species: Human
• Tag: N-His
• Form: Lyophilized powder/frozen liquid
• Molecular Mass: 27.88 kDa
• Protein Length: Gln357-Leu580
• Purity: >90% as determined by SDS-PAGE.
• Notes: For research use only.
• Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt.
• Storage Buffer: 0.01M PBS, pH 7.4, 0.02% NLS
• Reconstitution: Reconstitute in sterile water for a stock solution.
• Shipping: They are shipped out with dry ice/blue ice unless customers require otherwise.

Gene Information

• Gene Name: METTL3 methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit [ Homo sapiens (human) ]
• Official Symbol: METTL3
• Synonyms: METTL3; methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit; M6A; IME4; Spo8; MT-A70; hMETTL3
• Gene ID: 56339
• mRNA Refseq: NM_019852
• Protein Refseq: NP_062826
• MIM: 612472
• UniProt ID: Q86U44