Recombinant Human METTL3 Protein, His-tagged

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Recombinant Human METTL3 Protein, His-tagged

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Cat.No. : METTL3-12H
Product Overview : Recombinant human METTL3 protein (2-580) with a N-terminal His-tag and recombinant human METTL14(2-456) protein with a N-terminal GST/His-tag were expressed in insect cells.
Description : This gene encodes the 70 kDa subunit of MT-A which is part of N6-adenosine-methyltransferase. This enzyme is involved in the posttranscriptional methylation of internal adenosine residues in eukaryotic mRNAs, forming N6-methyladenosine.
Source : Insect cell
Species : Human
Tag : His
Form : 10 mM Tris, with 500 mM sodium chloride, 1 mM DTT, and 5% glycerol
Molecular Mass : 66.3 kDa
Protein length : 2-580
Purity : ≥80% estimated by SDS-PAGE
Applications : WB, ELISA
Stability : ≥ 1 year
Storage : Store at -80 centigrade
SDS-PAGE of METTL3/14 :

Lane 1: MW Markers, Lane 2: METTL3 and METTL14 (4 µg), Lane 3: METTL3 and METTL14 (2 µg)

Gene Name : METTL3 methyltransferase like 3 [ Homo sapiens (human) ]
Official Symbol : METTL3
Synonyms : METTL3; methyltransferase like 3; M6A; IME4; Spo8; MT-A70; hMETTL3; N6-adenosine-methyltransferase catalytic subunit; N6-adenosine-methyltransferase 70 kDa subunit; adoMet-binding subunit of the human mRNA (N6-adenosine)-methyltransferase; mRNA (2'-O-methyladenosine-N(6)-)-methyltransferase; mRNA m(6)A methyltransferase; methyltransferase-like protein 3
Gene ID : 56339
mRNA Refseq : NM_019852
Protein Refseq : NP_062826
MIM : 612472
UniProt ID : Q86U44
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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