Recombinant Human METTL3 Protein, GST-tagged

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Recombinant Human METTL3 Protein, GST-tagged

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Cat.No. : METTL3-838H
Product Overview : Human METTL3 full-length ORF ( NP_062826.2, 1 a.a. - 580 a.a.) recombinant protein with GST-tag at N-terminal.
Description : This gene encodes the 70 kDa subunit of MT-A which is part of N6-adenosine-methyltransferase. This enzyme is involved in the posttranscriptional methylation of internal adenosine residues in eukaryotic mRNAs, forming N6-methyladenosine.
Source : Wheat germ
Species : Human
Tag : GST
Form : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Molecular Mass : 90.9 kDa
AA Sequence : MSDTWSSIQA HKKQLDSLRE RLQRRRKQDS GHLDLRNPEA ALSPTFRSDS PVPTAPTSGG PKPSTASAVP ELATDPELEK KLLHHLSDLA LTLPTDAVSI CLAISTPDAP ATQDGVESLL QKFAAQELIE VKRGLLQDDA HPTLVTYADH SKLSAMMGAV AEKKGPGEVA GTVTGQKRRA EQDSTTVAAF ASSLVSGLNS SASEPAKEPA KKSRKHAASD VDLEIESLLN QQSTKEQQSK KVSQEILELL NTTTAKEQSI VEKFRSRGRA QVQEFCDYGT KEECMKASDA DRPCRKLHFR RIINKHTDES LGDCSFLNTC FHMDTCKYVH YEIDACMDSE APGSKDHTPS QELALTQSVG GDSSADRLFP PQWICCDIRY LDVSILGKFA VVMADPPWDI HMELPYGTLT DDEMRRLNIP VLQDDGFLFL WVTGRAMELG RECLNLWGYE RVDEIIWVKT NQLQRIIRTG RTGHWLNHGK EHCLVGVKGN PQGFNQGLDC DVIVAEVRST SHKPDEIYGM IERLSPGTRK IELFGRPHNV QPNWITLGNQ LDGIHLLDPD VVARFKQRYP DGIISKPKNL
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Figure :

Gene Name : METTL3 methyltransferase like 3 [ Homo sapiens (human) ]
Official Symbol : METTL3
Synonyms : IME4,M6A,MGC4336,MT-A70,Spo8
Gene ID : 56339
mRNA Refseq : NM_019852.3
Protein Refseq : NP_062826.2
MIM : 612472
UniProt ID : Q86U44

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