|Official Full Name||platelet derived growth factor D|
|Background||The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a core motif of eight cysteines, seven of which are found in this factor. This gene product only forms homodimers and, therefore, does not dimerize with the other three family members. It differs from alpha and beta members of this family in having an unusual N-terminal domain, the CUB domain. Two splice variants have been identified for this gene.|
|Synonyms||PDGFD; platelet derived growth factor D; platelet-derived growth factor D; IEGF; MSTP036; SCDGF B; spinal cord derived growth factor B; PDGF-D; iris-expressed growth factor; spinal cord-derived growth factor B; spinal cord-derived growth factor-B; SCDGFB; SCDGF-B|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
PDGFD involved in several pathways and played different roles in them. We selected most pathways PDGFD participated on our site, such as content, which may be useful for your reference. Also, other proteins which involved in the same pathway with PDGFD were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Ras signaling pathway||VEGFC; PLA2G2F; Fgf15; HTR7; ETS2; PLA2G12A; MET; GNG3; RALGDS; ANGPT4|
|Rap signaling pathway||PRKCG; LPAR3; FARP2; ITGAM; PARD3; FGF20; KRIT1; GRIN2B; SRC; CALM3|
|Phospholipase D signaling pathway||PPAP2C; PIK3CA; TSC2; ARF6; PIP5K1C; SOS1; PLA2G4A; AVPR2; AVPR1B; PPAP2A|
|PIK-Akt signaling pathway||GNGT1; LAMA5; DDIT4; COL6A5; PPP2R3C; TNC; EPOR; ITGB3; ATF4; FGF8|
|Focal adhesion||COL2A1B; BADB; COL2A1; PAK2B; CHAD; VTN; PRKCG; PPP1CA; ITGA3; SHC2|
|Gap junction||GNAQ; TUBB5; DRD2L; GNAIA; PRKACA; TUBA4A; TUBA8L3; MAP2K5; HRASB; NRAS|
|Regulation of actin cytoskeleton||ARPC5LA; CYFIP1; MOS; PDGFA; Itgam&Itgb2; ITGB1; WAS; PPP1CBL; CYFIP2; ARPC5B|
|Prostate cancer||MDM2; CCND1; PDGFRB; IGF1; TCF7; SPINK1; IGF1R; INS; ARID1A; PDGFD|
|Melanoma||PTEN; PDGFA; FGF22; TRP53; PDGFD; MAPK1; FGF18; FGF2; MET; Pdgfa&Pdgfb|
|Choline metabolism in cancer||MTOR; KRAS; WASF1; MAPK9; PIK3CG; PIP5K1A; DGKG; WASL; SP1; RHEB|
PDGFD has several biochemical functions, for example, Content. Some of the functions are cooperated with other proteins, some of the functions could acted by PDGFD itself. We selected most functions PDGFD had, and list some proteins which have the same functions with PDGFD. You can find most of the proteins on our site.
|growth factor activity||FGF21; NRG1; BMP16; FGF12B; BMP5; Fgf15; GH1; GDF10B; TGFB2; LEFTY2|
|platelet-derived growth factor receptor binding||PDGFA; IL1R1; PTEN; VEGFA; PDGFD; PTPRJ; PDGFB; Pdgfa&Pdgfb; PDGFC; PDGFAB|
PDGFD has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PDGFD here. Most of them are supplied by our site. Hope this information will be useful for your research of PDGFD.