pdgfd
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  • Official Full Name
  • platelet derived growth factor D
  • Background
  • The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a core motif of eight cysteines, seven of which are found in this factor. This gene product only forms homodimers and, therefore, does not dimerize with the other three family members. It differs from alpha and beta members of this family in having an unusual N-terminal domain, the CUB domain. Two splice variants have been identified for this gene.
  • Synonyms
  • PDGFD; platelet derived growth factor D; platelet-derived growth factor D; IEGF; MSTP036; SCDGF B; spinal cord derived growth factor B; PDGF-D; iris-expressed growth factor; spinal cord-derived growth factor B; spinal cord-derived growth factor-B; SCDGFB; SCDGF-B
Cat.#:PDGFD-1611HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PDGFD, His-tagged
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Cat.#:PDGFD-207HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human PDGFD, His tagged
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Cat.#:PDGFD-211HTag:N/A
Source (Host):NS0Species:Human
Product nameRecombinant Human PDGFD
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Cat.#:PDGFD-24HTag:
Source (Host):CHOSpecies:Human
Product nameRecombinant Human PDGFD protein
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Cat.#:PDGFD-12569MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse PDGFD Protein
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Cat.#:Pdgfd-390MTag:His/SUMO
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Pdgfd protein, His/SUMO-tagged
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Cat.#:PDGFD-4339RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat PDGFD Protein
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Cat.#:Pdgfd-8157RTag:His/T7
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Pdgfd protein, His & T7-tagged
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Cat.#:PDGFD-5169CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken PDGFD
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Cat.#:PDGFD-7140HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Platelet Derived Growth Factor D, His-tagged
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Cat.#:PDGFD-3335HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human PDGFD 293 Cell Lysate
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Cat.#:PDGFD-3336HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human PDGFD 293 Cell Lysate
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Involved Pathway

PDGFD involved in several pathways and played different roles in them. We selected most pathways PDGFD participated on our site, such as Ras signaling pathway, Rap signaling pathway, Phospholipase D signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with PDGFD were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Ras signaling pathway
GNB1; INS; GNG2; PRKCG; PLA2G2A; NGFR; IGF1; KSR2; PIK3CG; RHOA
Rap signaling pathway
NGFR; ITGB3; FGF3; FYB; P2RY1; HRAS; KRAS; RAPGEF1; FGF17; GRIN1
Phospholipase D signaling pathway
PDGFB; PTPN11; PLD1; RRAS; AGPAT5; PPAP2C; AGTR1A; PDGFRB; CYTH3; PLCB3
PIK-Akt signaling pathway
PHLPP2; ITGB7; KITLG; HSP90AB1; HSP90B1; FGF14; PRKAA2; ITGA10; OSM; PKN3
Focal adhesion
VEGFC; TLN1; VEGFA; TNXB; RAPGEF1; PRKCBA; PDGFRA; VAV3; TNK1; RAF1
Gap junction
ITPR3; GRB2; CX35B; HRASA; PDGFAA; TUBA1C; ADCY1A; TUBB; CSNK1DB; TUBA4L
Regulation of actin cytoskeleton
VCL; F2R; FN1A; PDGFB; FGF1B; GNG12A; MLCK2; ACTG1; FGF20B; RRAS
Prostate cancer
MAPK3; CREB5; AKT1; TRP53; PIK3R1; EP300; HSP90B1; Ar; TCF7; SMARCC2
Melanoma
ARAF; FGF22; FGF19; TP53; FGF17; AKT2; FGFR1; FGF10; FGF6; MAP2K2
Choline metabolism in cancer
SLC22A5; FOS; NRAS; PRKCA; PDGFRA; DGKA; PLA2G4D; PRKCG; PDGFB; MAP2K1

Protein Function

PDGFD has several biochemical functions, for example, growth factor activity, platelet-derived growth factor receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PDGFD itself. We selected most functions PDGFD had, and list some proteins which have the same functions with PDGFD. You can find most of the proteins on our site.
Function
Related Protein
Function growth factor activity
Related Protein MSTNB; CNTF; FGF13A; FGF6A; THBS4; AMELX; Pdgfa&Pdgfb; FGF8A; NRG3; CSF1
Function platelet-derived growth factor receptor binding
Related Protein LYN; PDGFD; PDGFRB; Pdgfa&Pdgfb; VEGFA; IL1R1; PDGFB; ITGB3; PDGFA; TYMP