stim1
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  • Official Full Name
  • stromal interaction molecule 1
  • Background
  • Ca2+ is a key second messenger in many intracellular signaling pathways. Ca2+ signals control many cellular functions ranging from short-term responses such as contraction and secretion to longer-term regulation of cell growth and proliferation. Stromal i
  • Synonyms
  • STIM1; stromal interaction molecule 1; D11S4896E; GOK; STIM1L
Cat.#:STIM1-2883HTag:Myc|DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human STIM1 Protein, MYC/DDK-tagged
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Cat.#:STIM1-3208HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human STIM1, His tagged
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Cat.#:STIM1-344HTag:CaM
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Stromal Interaction Molecule 1, CaM-tagged
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Cat.#:STIM1-4619HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Stromal Interaction Molecule 1
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Cat.#:STIM1-8132HTag:His|T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human STIM1 protein, His & T7-tagged
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Cat.#:STIM1-16128MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse STIM1 Protein
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Cat.#:STIM1-5788RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat STIM1 Protein
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Cat.#:STIM1-4523RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey STIM1 Protein, His-tagged
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Cat.#:STIM1-2534CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken STIM1
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Cat.#:STIM1-2277HCLTag:N/A
Source (Host):HEK293Species:Human
Product nameRecombinant Human STIM1 cell lysate
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Involved Pathway

STIM1 involved in several pathways and played different roles in them. We selected most pathways STIM1 participated on our site, such as Calcium signaling pathway, Platelet activation, which may be useful for your reference. Also, other proteins which involved in the same pathway with STIM1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Calcium signaling pathway
PRKACG; VDAC3; TRHR; ADORA2B; PRKACAB; P2RX4B; HTR7; TBXA2R; HTR5AL; ATP2B4
Platelet activation
GNAI3; FCGR2A; F2RL3; MAPK12; Adcy4; PLCB2; GUCY1A3; GNAQ; AKT2; TBXA2R

Protein Function

STIM1 has several biochemical functions, for example, calcium channel regulator activity, calcium ion binding, identical protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by STIM1 itself. We selected most functions STIM1 had, and list some proteins which have the same functions with STIM1. You can find most of the proteins on our site.
Function
Related Protein
Function calcium channel regulator activity
Related Protein NRXN1; HPCAL4; NRXN2; PRKG1; GRM6A; NRXN3; CACNA2D4; CACNA2D2; NPY2R; SGK3
Function calcium ion binding
Related Protein S100A8; RHOT1; CAPSLB; MICU2; SVEP1; PADI1; PCDH1G11; BMP1B; KCNIP3B; EEF2K
Function identical protein binding
Related Protein ADIPOR2; LTBR; ACPP; PLEKHH2; TPCN2; SOD2; MICU1; G6PD; MRI1; LRP6
Function microtubule plus-end binding
Related Protein CLASP1; STIM1; CLASP1A; CLIP2; KIF18A; MAPRE1; CLIP1; APC; KIF2C; DST
Function protease binding
Related Protein ITGB3; DPP4; ECM1; ELANE; TIMP1; STIM1; ITGAV; SERPINB9; TTN; FURIN
Function protein binding
Related Protein ANKFY1; TM4SF4; RAPGEF4; USP10; KRT1; ARID1A; PFTK1; ACAN; B2M; DUSP15

Interacting Protein

STIM1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with STIM1 here. Most of them are supplied by our site. Hope this information will be useful for your research of STIM1.
ORAI1

STIM1 Related Articles

Gaida, K; Salimi-Moosavi, H; et al. Inhibition of CRAC with a human anti-ORAI1 monoclonal antibody inhibits T-cell-derived cytokine production but fails to inhibit a T-cell-dependent antibody response in the cynomolgus monkey. JOURNAL OF IMMUNOTOXICOLOGY 12:164-173(2015).
Saliba, Y; Keck, M; et al. Emergence of Orai3 activity during cardiac hypertrophy. CARDIOVASCULAR RESEARCH 105:248-259(2015).