Slamf6 Protein, SLAM family member 6


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Official Full Name SLAM family member 6
Background The protein encoded by this gene is a type I transmembrane protein, belonging to the CD2 subfamily of the immunoglobulin superfamily. This encoded protein is expressed on Natural killer (NK), T, and B lymphocytes. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It functions as a coreceptor in the process of NK cell activation. It can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Synonyms SLAMF6; SLAM family member 6; lymphocyte antigen 108; KAL1; NTBA; KAL1b; Ly108; NTB-A; SF2000
    • Species :
    • Human
    • Mouse
    • Rhesus monkey
    • Source :
    • E.coli
    • HEK293
    • Human Cell
    • Tag :
    • Fc
    • GST
    • hIgG1
    • hIgG4
    • His
    • Avi
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Mouse Slamf6-144M Recombinant Mouse Slamf6 Protein, His-tagged HEK293 His
    Human SLAMF6-242H Recombinant Human SLAMF6 Protein, His-Avi-tagged, Biotinylated HEK293 His/Avi
    Human SLAMF6-235H Recombinant Human SLAMF6, LEVLFQ tagged Human Cell GST
    Human SLAMF6-241H Recombinant Human SLAMF6 protein, His-tagged HEK293 His
    Human SLAMF6-269H Recombinant Human SLAMF6, Fc tagged Human Cell GST
    Human SLAMF6-374H Recombinant Human SLAM family member 6, His-tagged E.coli His
    Human SLAMF6-3945H Recombinant Human SLAMF6, His tagged Human Cell His
    Human SLAMF6-687H Recombinant Human SLAMF6, Fc-tagged, Biotinylated Human Cell Fc
    Human SLAMF6-913HCL Recombinant Human SLAMF6 cell lysate Human Cell N/A
    Mouse SLAMF6-2108MCL Recombinant Mouse SLAMF6 cell lysate Human Cell N/A
    Mouse Slamf6-4020M Recombinant Mouse Slamf6, His tagged Human Cell His
    Rhesus monkey SLAMF6-1773R Recombinant Rhesus Monkey SLAMF6 Protein HEK293 N/A
    Rhesus monkey SLAMF6-1774R Recombinant Rhesus Monkey SLAMF6 Protein, hIgG1-tagged HEK293 hIgG1
    Rhesus monkey SLAMF6-1775R Recombinant Rhesus Monkey SLAMF6 Protein, hIgG4-tagged HEK293 hIgG4

    Slamf6 involved in several pathways and played different roles in them. We selected most pathways Slamf6 participated on our site, such as Adaptive Immune System, Immune System, Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell, which may be useful for your reference. Also, other proteins which involved in the same pathway with Slamf6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Adaptive Immune System FBXO27; SIGLEC10; MAPKAP1; AGO3; ITK; EGF; DZIP3; RNF111; AGO2; KLRG1
    Immune System CLEC2H; TRAF7; BTR18; SEC24A; EIF4G2A; SLAMF6; DCTN6; CFHL1; FBXO17; TREML4
    Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell LAIR2; CLEC2D; SLAMF6; CD300LH; RAET1E; LILRA3; TREM1; CD300LF; SIGLEC5; SIGLEC7

    Slamf6 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Slamf6 itself. We selected most functions Slamf6 had, and list some proteins which have the same functions with Slamf6. You can find most of the proteins on our site.

    Function Related Protein
    protein binding SH2D2A; PPP6R2; FKBP6; HSP90AA1; SORBS2; ZBTB22; DAXX; ACTR8; KRTAP5-9; NRG4

    Slamf6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Slamf6 here. Most of them are supplied by our site. Hope this information will be useful for your research of Slamf6.

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