TNC

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TNC

Official Full Name tenascin C
Background Tenascins are extracellular matrix glycoproteins. They are abundant in the extracellular matrix of developing vertebrate embryos and they reappear around healing wounds and in the stroma of some tumors.
Synonyms Tenascin-X; tenascin XB1; tenascin XB2; OTTHUMP00000174881; tenascin XB; OTTHUMP00000216549; hexabrachion-like protein; growth-inhibiting protein 45; XB; TNX; XBS; HXBL; TENX; TN-X; TNXB1; TNXB2; TNXBS; TNXB
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rabbit
    • Rat
    • Zebrafish
    • Source :
    • E. coli
    • E.coli
    • Mammalian Cell
    • NS0
    • Wheat Germ
    • Yeast
    • Tag :
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human TNC-311H Recombinant Human Transthyretin (Wild Type) Protein, 13C, 15N Label E. coli N/A
    Human TNC-32H Recombinant Human TNC Protein, His-tagged E.coli His
    Mouse TNC-2566M Recombinant Mouse TNC Protein (1884-2099 aa), His-tagged Yeast His
    Human TNC-31215TH Recombinant Human TNC Wheat Germ N/A
    Human TNC-50H Native Human Tenascin C N/A
    Human TNC-734H Recombinant Human TNC, His-tagged NS0 His
    Mouse Tnc-2051M Recombinant Mouse Tnc protein, His-tagged E.coli His
    Rat Tnc-2052R Recombinant Rat Tnc protein, His-tagged E.coli His
    Rabbit TNC-256R Recombinant Rabbit Cardiac Troponin C E.coli N/A
    Chicken TNC-7006C Recombinant Chicken TNC Mammalian Cell His
    Zebrafish TNC-8548Z Recombinant Zebrafish TNC Mammalian Cell His

    TNC involved in several pathways and played different roles in them. We selected most pathways TNC participated on our site, such as PIK-Akt signaling pathway, Focal adhesion, ECM-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with TNC were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    PIK-Akt signaling pathway PRKAA2; IBSP; PKN3; CCNE2; FGF11; ITGA9; IFNA6; PCK1; VEGFA; THBS1
    Focal adhesion VEGFA; PAK4; ITGA2B; MYL5; FN1A; GRB2A; ITGA4; FLNB; MYL12.1; TNK2
    ECM-receptor interaction LAMA1; GP5; THBS4B; FN1; COL27A1A; SV2A; VWF; LAMB1; COL3A1; COL6A6
    MicroRNAs in cancer GRB2; IRS2; Casp3; APC2; WNT3A; DDIT4; GLS; MMP16; MMP9; GLS2

    TNC has several biochemical functions, for example, syndecan binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TNC itself. We selected most functions TNC had, and list some proteins which have the same functions with TNC. You can find most of the proteins on our site.

    Function Related Protein
    syndecan binding SDCBP; CHRD; HPSE; TNC; SEMA5A

    TNC has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TNC here. Most of them are supplied by our site. Hope this information will be useful for your research of TNC.

    Pezzolo, A; Marimpietri, D; et al. Failure of anti tumor-derived endothelial cell immunotherapy depends on augmentation of tumor hypoxia. ONCOTARGET 5:10368-10381(2014).
    Alessio, GD; Cortes, DF; et al. Innovations in diagnosis and post-therapeutic monitoring of Chagas disease: Simultaneous flow cytometric detection of IgG1 antibodies anti-live amastigote, anti-live trypomastigote, and anti-fixed epimastigote forms of Trypanosoma cruzi. JOURNAL OF IMMUNOLOGICAL METHODS 413:32-44(2014).

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