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WFDC2

  • Official Full Name

    WAP four-disulfide core domain 2

  • Overview

    This gene encodes a protein that is a member of the WFDC domain family. The WFDC domain, or WAP Signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. This gene is expressed in pulmonary epithelial cells, and was also found to be expressed in some ovarian cancers. The encoded protein is a small secretory protein, which may be involved in sperm maturation. [provided by RefSeq, Jul 2008]
  • Synonyms

    WFDC2; WAP four-disulfide core domain 2; HE4; WAP5; EDDM4; dJ461P17.6; WAP four-disulfide core domain protein 2; epididymal protein 4; epididymal secretory protein E4; putative protease inhibitor WAP5; WAP domain containing protein HE4-V4; major epididymis-specific protein E4; epididymis-specific, whey-acidic protein type, four-disulfide core;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Antibody
  • Protein Pre-coupled Magnetic Beads
  • Canine
  • Human
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • HEK293T
  • Human Cell
  • Mammalian Cell
  • Mammalian cells
  • Mouse
  • C
  • His
  • Flag
  • His (Fc)
  • Avi
  • His|Avi
  • His|GST
  • HlgG1 Fc
  • Myc
  • DDK
  • Myc|DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human WFDC2-55H Recombinant Human WFDC2 protein, His-tagged E.coli His
Human WFDC2-159H Recombinant Human WFDC2 protein, His-tagged HEK293 His Glu31-Phe124
Human WFDC2-3982H Recombinant Human WFDC2 protein, His-tagged HEK293 His Met1-Phe124
Human WFDC2-287H Recombinant Human WFDC2 Protein, His/GST-tagged E.coli His/GST Ala30~Phe124
Human WFDC2-2056HCL Recombinant Human WFDC2 cell lysate Human Cell N/A
Human WFDC2-361H Recombinant Human WFDC2 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human WFDC2-3983H Recombinant Human WFDC2 Protein, His-Avi-tagged, Biotinylated HEK293 His/Avi
Human WFDC2-649HFL Recombinant Full Length Human WFDC2 Protein, C-Flag-tagged Mammalian cells Flag
Human CAB11627MH Mouse Monoclonal Antibody to Human WAP Four-Disulfide Core Domain 2 Mouse N/A
Human WFDC2-2662H Recombinant Human WFDC2 protein, His-tagged HEK293 His Glu31-Phe124
Human WFDC2-2356H Recombinant Human WFDC2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human WFDC2-3415H Recombinant Human WFDC2 Protein (Met1-Phe124), C-His tagged Mammalian cells C-His Met1-Phe124
Human WFDC2-663H Recombinant Hmuan WFDC2 protein E.coli N/A 94
Human WFDC2-5532H Recombinant Human WFDC2 Protein (Glu31-Phe124), N-His tagged E.coli N-His Glu31-Phe124
Human WFDC2-281H Recombinant Human WFDC2 Protein, His-tagged HEK293 His 124
Human WFDC2-2356H-B Recombinant Human WFDC2 Protein Pre-coupled Magnetic Beads HEK293
Mouse Wfdc2-894M Recombinant Mouse Wfdc2 Protein, His-tagged HEK293 His
Mouse Wfdc2-6996M Recombinant Mouse Wfdc2 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat WFDC2-6587R Recombinant Rat WFDC2 Protein Mammalian Cell His
Rat WFDC2-6243R Recombinant Rat WFDC2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat WFDC2-6243R-B Recombinant Rat WFDC2 Protein Pre-coupled Magnetic Beads HEK293
Canine WFDC2-1266CCL Recombinant Canine WFDC2 cell lysate Human Cell N/A
Canine WFDC2-916C Recombinant Canine WFDC2 Protein (Met1-Phe124), HlgG1 Fc-tagged HEK293 HlgG1 Fc Met1-Phe124
  • Involved Pathway
  • Protein Function
  • Interacting Protein

WFDC2 involved in several pathways and played different roles in them. We selected most pathways WFDC2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with WFDC2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

WFDC2 has several biochemical functions, for example, aspartic-type endopeptidase inhibitor activity, cysteine-type endopeptidase inhibitor activity, endopeptidase inhibitor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by WFDC2 itself. We selected most functions WFDC2 had, and list some proteins which have the same functions with WFDC2. You can find most of the proteins on our site.

Function Related Protein
aspartic-type endopeptidase inhibitor activity
cysteine-type endopeptidase inhibitor activitySERPINB3;LCN1;CARD16;NAIP1;AHSG;CST1;CST9;PTTG1;CST8
endopeptidase inhibitor activityC3B.2;C3;LPA;C3A.3;SERPINA1E;SERPINF2;MUG2;Serpina1b;STFA1
serine-type endopeptidase inhibitor activitySERPINH1;OVAL;SPINK2;COL6A3;SERPINA1;SPINK6;PCSK1NL;SERPINA11;SERPINA1E

WFDC2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with WFDC2 here. Most of them are supplied by our site. Hope this information will be useful for your research of WFDC2.

Ikbip; PTN

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