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ALPP

  • Official Full Name

    ALPP alkaline phosphatase, placental

  • Synonyms

    ALPP; alkaline phosphatase, placental; alkaline phosphatase, placental (Regan isozyme); alkaline phosphatase, placental type; Regan isozyme; PLAP-1; glycerophosphatase; alkaline phosphomonoesterase; placental alkaline phosphatase 1; alkaline phosphatase Regan isozyme; ALP; PALP; PLAP; FLJ61142;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Antibody
  • Protein Pre-coupled Magnetic Beads
  • Native Proteins
  • Cynomolgus
  • Homo sapiens (Human)
  • Human
  • Rat
  • E.coli
  • E.coli expression system
  • HEK293
  • HEK293T
  • Human Placenta
  • In Vitro Cell Free System
  • Insect Cell
  • Mammalian cells
  • Mouse
  • Placental
  • Rabbit
  • Wheat Germ
  • Yeast
  • C
  • His
  • Flag
  • GST
  • His (Fc)
  • Avi
  • His|T7
  • Myc
  • DDK
  • N/A
  • N
  • T7|His
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human ALPP-53H Recombinant Human ALPP E.coli N/A
Human ALPP-219H Recombinant Human ALPP, His-tagged Yeast His Ile23-Asp506
Human ALPP-221H Recombinant Human ALPP protein, T7/His-tagged E.coli T7/His
Human ALPP-302H Recombinant Human ALPP Protein, His tagged HEK293 C-His
Human ALPP-495H Recombinant Human ALPP Protein, GST-tagged Wheat Germ GST
Human ALPP-8893HCL Recombinant Human ALPP 293 Cell Lysate HEK293 N/A
Human ALPP-2511H Recombinant Human ALPP protein, His-tagged E.coli His 117-447aa
Human ALPP-30162H Recombinant Human ALPP protein, GST-tagged E.coli GST Ser199-Pro535
Human ALPP-2197H Recombinant Human ALPP protein, His-tagged Insect Cell His 117-447aa
Human ALPP-1821H Recombinant Human ALPP Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human ALPP-124H Recombinant Human ALPP Protein, His-tagged E.coli N-His Ile23-Asp506
Human ALPP-67H Recombinant Human ALPP Protein, His-tagged HEK293 His
Human CAB-921RH Mouse Anti-Human Placental Alkaline Phosphatase Monoclonal Antibody (Placenta) Mouse N/A
Human ALPP-329H-B Recombinant Human ALPP Protein Pre-coupled Magnetic Beads HEK293
Human ALPP-125H Recombinant Human ALPP Protein, His-tagged E.coli N-His Arg249-Met484
Human ALPP-0309H Recombinant Human ALPP Protein (Ile23-Asp506), C-His-tagged Mammalian cells C-His Ile23-Asp506
Human CAB-920RH Rabbit Anti-Human Placental Alkaline Phosphatase Monoclonal Antibody(Spermatogenium) Rabbit N/A
Human ALPP-1487HF Recombinant Full Length Human ALPP Protein, GST-tagged In Vitro Cell Free System GST 535 amino acids
Human ALPP-150HFL Recombinant Full Length Human ALPP Protein, C-Flag-tagged Mammalian cells Flag
Human ALPP-329H Recombinant Human ALPP Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human ALPP-8347H Native Human ALPP Placental N/A
Human ALPP-8005H Native Human Placental Alkaline Phosphatase Human Placenta N/A
Rat Alpp-5823R Recombinant Rat Alpp protein, His & T7-tagged E.coli His/T7 Thr68~Ala313 (Accession # D4ADM6)
Cynomolgus ALPP-2860C Recombinant Cynomolgus ALPP protein, His-tagged HEK293 His Ile 21-Asn 504
Homo sapiens (Human) RFL-27321HF Recombinant Full Length Human Alkaline Phosphatase, Placental Type(Alpp) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (23-506)
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • ALPP Related Research Area

ALPP involved in several pathways and played different roles in them. We selected most pathways ALPP participated on our site, such as Folate biosynthesis, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with ALPP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Folate biosynthesisPTS;FPGS;QDPRB1;SPRA;ALPP;ALPI;QDPRB2;QDPRA;SPR
Metabolic pathwaysSAT1;CDO1;ST6GALNAC4;GALNTL1;CMASA;AKR1A1B;PMVK;PLD1A;FUT9A

ALPP has several biochemical functions, for example, alkaline phosphatase activity, magnesium ion binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ALPP itself. We selected most functions ALPP had, and list some proteins which have the same functions with ALPP. You can find most of the proteins on our site.

Function Related Protein
alkaline phosphatase activityALPL;ALPP;ALPI;ALPI.1;ALPPL2;ALP3
magnesium ion bindingCIB4;PRPSAP1;WEE2;THTPA;FAN1;PRPS1L1;MARK1;IMPA2;PPA1
protein bindingGPRASP1;YBX1;CDC40;ST8SIA5;F7;GYS1;PRX;ATP6V1D;ANXA2
zinc ion bindingTRIM28;BMI1A;ADAM5;ZNF385D;MGRN1;MAN2A1;GALT;SIAH2L;CIZ1B

ALPP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ALPP here. Most of them are supplied by our site. Hope this information will be useful for your research of ALPP.

KRTAP5-9; KRTAP4-12; GPAA1; Cbx1; Erh; Cep76; Trim69; PIGK; A2M; SUMO3; SUMO1

  • Q&As
  • Reviews

Q&As (10)

Ask a question
Can ALPP serve as a diagnostic biomarker or therapeutic target for specific diseases? 01/26/2022

ALPP may serve as a diagnostic biomarker for specific diseases, allowing for disease detection and monitoring, and its targeting could hold therapeutic potential in certain pathological conditions.

How does ALPP contribute to the metabolism and turnover of its substrate(s) in physiological and pathological conditions? 11/28/2021

ALPP participates in the metabolism and turnover of its substrate(s), including the hydrolysis of phosphoester bonds and the regulation of cellular phosphate homeostasis.

What are the downstream signaling pathways and molecular interactions regulated by ALPP in cellular functions? 12/22/2020

ALPP regulates downstream signaling pathways and molecular interactions involved in cellular processes like phosphate metabolism, intracellular signaling, and extracellular matrix remodeling.

What are the regulatory mechanisms controlling ALPP gene expression and enzyme activity? 12/15/2020

ALPP gene expression is regulated by transcription factors, epigenetic modifications, and signaling pathways involved in cellular homeostasis and disease processes.

What is the subcellular localization and trafficking of ALPP within cells? 11/09/2019

ALPP is localized to specific cellular compartments, such as the plasma membrane, endoplasmic reticulum, or lysosomes, and its trafficking may be regulated by sorting signals and intracellular transport machinery.

Can ALPP activity be modulated by specific factors or inhibitors, and how does this impact cellular processes? 07/17/2019

ALPP activity can be modulated by factors such as pH, calcium, and inhibitors, which can affect its catalytic efficiency and cellular functions.

How does ALPP deficiency or dysregulation contribute to the pathogenesis of diseases and disorders? 07/16/2019

ALPP deficiency or dysregulation is associated with various diseases, including metabolic disorders, bone diseases, and certain cancers, highlighting its pathological implications.

How can ALPP activity and function be manipulated to modulate cellular processes and disease outcomes? 09/12/2018

Manipulating ALPP activity and function could offer strategies to modulate cellular processes and disease outcomes, potentially leading to therapeutic interventions and improved patient outcomes.

How does ALPP expression and activity change during development, differentiation, and disease progression? 07/08/2018

ALPP expression and activity exhibit dynamic changes during development, cellular differentiation, and disease progression, reflecting its roles in different physiological and pathological contexts.

What is the expression pattern of ALPP in different tissues and cell types? 01/28/2017

ALPP shows a tissue-specific expression pattern, with higher levels in tissues such as liver, bone, and kidney, and lower levels in other organs.

Customer Reviews (3)

Write a review
Reviews
12/01/2020

    High-throughput screening compatibility.

    11/05/2018

      Consistent protein expression analysis.

      10/25/2017

        Precise protein quantification in ELISA.

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