Recombinant Human ALPP Protein, His-tagged

• Cat.No.: ALPP-67H
• Product Overview: Recombinant Human Alkaline Phosphatase is produced by our Mammalian expression system and the target gene encoding Ile23-Asp506 is expressed with a 6His tag at the C-terminus.

Specification

• Description: Alkaline phosphatase (ALPP) is a membrane protein that exists as a homodimer. ALPP is expressed only in normal-term placenta, endocervix and fallopian tube, as well as in ovarian and proximal gastrointestinal tumors. It has been demonstrated to play a role in various biological processes including cell signaling, long-term potentiation, and cell adhesion. In addition, ALPP has been found to correlate with cognitive function loss in Alzheimer's disease (AD).
• Source: HEK293
• Species: Human
• Tag: His
• Form: Supplied as a 0.2 um filtered solution of 20mM Tris-Hcl, 150mM NaCl, 0.2mM CaCl2, 10% Glycerol, pH7.5.
• Molecular Mass: Predicted Molecular Weight: 53.5kDa
  Apparent Molecular Weight: 45-66.2kDa, reducing conditions.
• AA Sequence: Ile23-Asp506
• Endotoxin: Less than 0.1 EU/ug.
• Purity: 85% as determined by SDS-PAGE
• Storage: Store at ≤-70 centigrade, stable for 6 months after receipt.
  Store at ≤-70 centigrade, stable for 3 months under sterile conditions after opening.
  Please minimize freeze-thaw cycles.
• Quality Statement: Purity: 85% as determined by SDS-PAGE.
• Shipping: The product is shipped at ambient temperature.
  Upon receipt, store it immediately at the temperature listed below.

Gene Information

• Gene Name: ALPP alkaline phosphatase, placental [ Homo sapiens (human) ]
• Official Symbol: ALPP
• Synonyms: Alkaline phosphatase; placental type; Alkaline phosphatase Regan isozyme; Placental alkaline phosphatase 1; ALPP; PLAP; ALP; IAP; ALPI; PLAP-1
• Gene ID: 250
• mRNA Refseq: NM_001632.5
• Protein Refseq: NP_001623.3
• MIM: 171800
• UniProt ID: P05187