asgr1

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asgr1

Official Full Name asialoglycoprotein receptor 1
Background This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. The protein encoded by this gene is the more abundant major subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]
Synonyms ASGR1; asialoglycoprotein receptor 1; HL-1; ASGPR; ASGPR1; CLEC4H1; hepatic lectin H1; C-type lectin domain family 4 member H1;
    • Species :
    • Human
    • Mouse
    • Rat
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Human Cell
    • Mammalian Cell
    • NS0
    • Wheat Germ
    • Tag :
    • C-Myc/DDK
    • GST
    • His
    • T7
    • MYC/DDK
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ASGR1-089H Recombinant Human ASGR1 Protein, MYC/DDK-tagged, C13 and N15-labeled HEK293 C-Myc/DDK
    Human ASGR1-1601HCL Recombinant Human ASGR1 cell lysate Human Cell N/A
    Human ASGR1-249H Recombinant Human ASGR1 Protein, His-tagged HEK293 His
    Human ASGR1-26517TH Recombinant Human ASGR1, His-tagged E.coli His
    Human ASGR1-2816H Recombinant Human ASGR1 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human ASGR1-586H Recombinant Human ASGR1, His-tagged NS0 His
    Human ASGR1-587H Recombinant Human ASGR1, GST-tagged Wheat Germ GST
    Human ASGR1-588H Recombinant Human ASGR1, GST-tagged E.coli GST
    Human ASGR1-589H Recombinant Human ASGR1, His-tagged Human Cell His
    Mouse Asgr1-2335M Recombinant Mouse Asgr1, His tagged Human Cell His
    Mouse ASGR1-3084MCL Recombinant Mouse ASGR1 cell lysate Human Cell N/A
    Mouse Asgr1-5782M Recombinant Mouse Asgr1 protein, His & T7-tagged E.coli His/T7
    Mouse Asgr1-656M Recombinant Mouse Asgr1 Protein, MYC/DDK-tagged HEK293T MYC/DDK
    Rat ASGR1-820R Recombinant Rat ASGR1 Protein Mammalian Cell His

    asgr1 involved in several pathways and played different roles in them. We selected most pathways asgr1 participated on our site, such as Thyroid hormone synthesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with asgr1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Thyroid hormone synthesis HSP90B1; PRKCB; PLCB2; CREB3L3; PDIA4; GPX6; SLC5A5; ASGR1; ITPR3; CREB3L1

    asgr1 has several biochemical functions, for example, asialoglycoprotein receptor activity, carbohydrate binding, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by asgr1 itself. We selected most functions asgr1 had, and list some proteins which have the same functions with asgr1. You can find most of the proteins on our site.

    Function Related Protein
    asialoglycoprotein receptor activity ASGR1; ASGR2; LRPAP1
    carbohydrate binding KLRK1; GCKR; C15orf24; ZP3; CNTN1; LPHN1; KLRC2; CLEC12A; CLEC4E; GALM
    metal ion binding METAP2; TRERF1; NRXN2; RPS27A; ZFP146; ZNF285A; ZFR; ZFP654; ZFP382; ZNF518A
    protein binding STX11; HIST1H3H; KIF7; AKAP8L; SESN2; ZBP1; SPRY4; DPF2; BRD2; MUSK
    protein homodimerization activity EXT1; UGT1A9; BMPR1A; TCF3A; HLA-G; GPD1L; TPD52; EEA1; PPP2R4; ACCS

    asgr1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with asgr1 here. Most of them are supplied by our site. Hope this information will be useful for your research of asgr1.

    CERS2; HIVEP1; CLEC4G; RBBP6; NLK

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