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BECN1

  • Official Full Name

    beclin 1, autophagy related

  • Overview

    Beclin-1 participates in the regulation of autophagy and has an important role in development, tumorigenesis, and neurodegeneration
  • Synonyms

    BECN1; beclin 1, autophagy related; ATG6; VPS30; beclin1; beclin 1 (coiled-coil, moesin-like BCL2 interacting protein); ATG6 autophagy related 6 homolog (S. cerevisiae); Beclin-1; Coiled-coil myosin-like BCL2-interacting protein; Protein GT197; GT197; ATG6 autophagy related 6 homolog; ATG6; VPS30; beclin1; Bcl-2-interacting protein beclin;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • His|MBP
  • His|SUMO
  • Myc
  • DDK
  • N/A
  • N
  • Tag Free
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human BECN1-295H Recombinant Human BECN1 protein, His/MBP-tagged E.coli His/MBP 127-268 aa
Human BECN1-10203H Recombinant Human BECN1, GST-tagged E.coli GST C-term-310a.a.
Human BECN1-294H Recombinant Human BECN1 protein, His/MBP-tagged E.coli His/MBP 342-428 aa
Human BECN1-189H Recombinant Human BECN1 Protein, GST-tagged Wheat Germ GST
Human BECN1-296H Recombinant Human BECN1 protein, His/MBP-tagged E.coli His/MBP 1-121 aa
Human BECN1-377H Recombinant Human beclin 1, autophagy related, His-tagged E.coli His
Human BECN1-190H Recombinant Human BECN1 Protein, GST-tagged Wheat Germ GST
Human BECN1-8470HCL Recombinant Human BECN1 293 Cell Lysate HEK293 N/A
Human BECN1-3340H Recombinant Human BECN1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human BECN1-445H Recombinant Human BECN1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human BECN1-2778H Recombinant Human BECN1 protein, His-tagged E.coli His 141-450 aa
Human BECN1-161HFL Active Recombinant Full Length Human BECN1 Protein, C-Flag-tagged Mammalian cells Flag
Human BECN1-1567HF Recombinant Full Length Human BECN1 Protein, GST-tagged In Vitro Cell Free System GST 450 amino acids
Human BECN1-0745H Recombinant Human BECN1 Protein E.coli Tag Free
Human BECN1-445H-B Recombinant Human BECN1 Protein Pre-coupled Magnetic Beads HEK293
Human BECN1-0746H Recombinant Human BECN1 Protein (Gln13-Gln239), N-His tagged E.coli N-His Gln13-Gln239
Mouse BECN1-2370M Recombinant Mouse BECN1 Protein Mammalian Cell His
Mouse Becn1-1855M Recombinant Mouse Becn1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse BECN1-2059M Recombinant Mouse BECN1 Protein (1-448 aa), His-SUMO-tagged E.coli His/SUMO 1-448 aa
Mouse BECN1-1008M Recombinant Mouse BECN1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse BECN1-1008M-B Recombinant Mouse BECN1 Protein Pre-coupled Magnetic Beads HEK293
Rat BECN1-967R Recombinant Rat BECN1 Protein Mammalian Cell His
Rat BECN1-625R-B Recombinant Rat BECN1 Protein Pre-coupled Magnetic Beads HEK293
Rat BECN1-625R Recombinant Rat BECN1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque BECN1-529R Recombinant Rhesus monkey BECN1 Protein, His-tagged Mammalian Cell His
Rhesus Macaque BECN1-357R-B Recombinant Rhesus Macaque BECN1 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque BECN1-357R Recombinant Rhesus Macaque BECN1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish BECN1-11120Z Recombinant Zebrafish BECN1 Mammalian Cell His
Chicken BECN1-1476C Recombinant Chicken BECN1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • BECN1 Related Research Area

BECN1 involved in several pathways and played different roles in them. We selected most pathways BECN1 participated on our site, such as Regulation of autophagy, which may be useful for your reference. Also, other proteins which involved in the same pathway with BECN1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Regulation of autophagyIFNA17;ATG4B;IFNA7;ATG14;ULK1;IFNA1;ATG5;BECN1;INS2

BECN1 has several biochemical functions, for example, phosphatidylinositol 3-kinase binding, protein binding, ubiquitin protein ligase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by BECN1 itself. We selected most functions BECN1 had, and list some proteins which have the same functions with BECN1. You can find most of the proteins on our site.

Function Related Protein
phosphatidylinositol 3-kinase bindingFYN;IGF1RB;INSRB;DAB1;PIK3R1;INSRA;INSR;LCK;IRS1
protein bindingSUN1;SORCS1;RPRD1B;KLRB1F;LIN7A;UBE2D3;WIBG;XAGE3;YIF1A
ubiquitin protein ligase bindingRRAGA;YWHAZ;LRPPRC;BRCA1;CUL2;SNX9;DLG3;PARK2;SCAMP3

BECN1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BECN1 here. Most of them are supplied by our site. Hope this information will be useful for your research of BECN1.

ATG14

  • Q&As
  • Reviews

Q&As (7)

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What role does BECN1 play in cancer biology? 12/29/2022

BECN1 is involved in cancer, influencing both tumor suppression and survival.

How does BECN1 contribute to cellular homeostasis? 10/20/2022

It helps maintain cellular health by regulating the degradation and recycling of cellular components.

What is the primary role of BECN1 in autophagy? 09/23/2021

BECN1, a key autophagy protein, initiates the autophagic process, crucial for cellular waste disposal.

How does BECN1 interact with other autophagy-related proteins? 07/10/2019

BECN1 interacts with a network of autophagy proteins, coordinating the autophagic response.

What is the impact of altered BECN1 activity on neurodegenerative diseases? 12/12/2018

Altered BECN1 activity is linked to neurodegeneration, as autophagy is essential for neuronal health.

What potential therapeutic applications arise from targeting BECN1 in disease treatment? 02/12/2018

Targeting BECN1 could provide new treatments for cancer and neurodegenerative diseases by modulating autophagy.

How do genetic variations in BECN1 affect autophagy? 08/11/2017

Genetic mutations in BECN1 can lead to dysfunctional autophagy, affecting cell survival and health.

Customer Reviews (3)

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Reviews
09/15/2022

    Top-notch analysis, enhances research outcomes.

    02/11/2022

      Reliable data source, trusted for data accuracy.

      04/08/2018

        Expertise shines, a critical research resource.

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