Recombinant Mouse Becn1 Protein, Myc/DDK-tagged
Cat.No. : | Becn1-1855M |
Product Overview : | Purified recombinant protein of mouse full-length beclin 1, autophagy related (Becn1), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | Plays a central role in autophagy. Acts as core subunit of different PI3K complex forms that mediate formation of phosphatidylinositol 3-phosphate and are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2. Essential for the formation of PI3KC3-C2 but not PI3KC3-C1 PI3K complex forms. Involved in endocytosis including endosome formation in neuronal cells. May play a role in antiviral host defense. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 52 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Becn1 beclin 1, autophagy related [ Mus musculus (house mouse) ] |
Official Symbol : | Becn1 |
Synonyms : | BECN1; beclin 1, autophagy related; beclin-1; Bcl-2-interacting protein beclin; coiled-coil myosin-like BCL2-interacting protein; coiled-coil, myosin-like BCL2-interacting protein; Atg6; MGC6843; 4921513J16Rik; 5430417M23Rik |
Gene ID : | 56208 |
mRNA Refseq : | NM_019584 |
Protein Refseq : | NP_062530 |
UniProt ID : | O88597 |
Products Types
◆ Recombinant Protein | ||
BECN1-625R | Recombinant Rat BECN1 Protein, His (Fc)-Avi-tagged | +Inquiry |
BECN1-2059M | Recombinant Mouse BECN1 Protein (1-448 aa), His-SUMO-tagged | +Inquiry |
BECN1-357R | Recombinant Rhesus Macaque BECN1 Protein, His (Fc)-Avi-tagged | +Inquiry |
BECN1-1008M | Recombinant Mouse BECN1 Protein, His (Fc)-Avi-tagged | +Inquiry |
BECN1-445H | Recombinant Human BECN1 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
BECN1-8470HCL | Recombinant Human BECN1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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