Active Recombinant Full Length Human BECN1 Protein, C-Flag-tagged
Cat.No. : | BECN1-161HFL |
Product Overview : | Recombinant Full Length Human BECN1 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol-3-kinase (PI3K) complex which mediates vesicle-trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants. |
Source : | Mammalian cells |
Species : | Human |
Tag : | Flag |
Form : | 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Bio-activity : | Enzyme substrate |
Molecular Mass : | 51.7 kDa |
AA Sequence : | MEGSKTSNNSTMQVSFVCQRCSQPL KLDTSFKILDRVTIQELTAPLLTTA QAKPGETQEEETNSGEEPFI ETPRQDGVSRRFIPPARMMSTESAN SFTLIGEASDGGTMENLSRRLKVTG DLFDIMSGQTDVDHPLCEEC TDTLLDQLDTQLNVTENECQNYKRC LEILEQMNEDDSEQLQMELKELALE EERLIQELEDVEKNRKIVAE NLEKVQAEAERLDQEEAQYQREYSE FKRQQLELDDELKSVENQMRYAQTQ LDKLKKTNVFNATFHIWHSG QFGTINNFRLGRLPSVPVEWNEINA AWGQTVLLLHALANKMGLKFQRYRL VPYGNHSYLESLTDKSKELP LYCSGGLRFFWDNKFDHAMVAFLDC VQQFKEEVEKGETRFCLPYRMDVEK GKIEDTGGSGGSYSIKTQFN SEEQWTKALKFMLTNLKWGLAWVSS QFYNKTRTRPLEQKLISEEDLAAND ILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining. |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade. |
Concentration : | >50 ug/mL as determined by microplate BCA method. |
Preparation : | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Protein Families : | Druggable Genome |
Protein Pathways : | Regulation of autophagy |
Gene Name : | BECN1 beclin 1 [ Homo sapiens (human) ] |
Official Symbol : | BECN1 |
Synonyms : | ATG6; VPS30; beclin1 |
Gene ID : | 8678 |
mRNA Refseq : | NM_003766.5 |
Protein Refseq : | NP_003757.1 |
MIM : | 604378 |
UniProt ID : | Q14457 |
Products Types
◆ Recombinant Protein | ||
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BECN1-2059M | Recombinant Mouse BECN1 Protein (1-448 aa), His-SUMO-tagged | +Inquiry |
Becn1-1855M | Recombinant Mouse Becn1 Protein, Myc/DDK-tagged | +Inquiry |
BECN1-445H | Recombinant Human BECN1 Protein, His (Fc)-Avi-tagged | +Inquiry |
BECN1-625R | Recombinant Rat BECN1 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
BECN1-8470HCL | Recombinant Human BECN1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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