BIRC7 Protein


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Official Full Name baculoviral IAP repeat containing 7
Background PUMA (p53 up-regulated modulator of apoptosis) is one of the pro-apoptotic Bcl-2 family members that are also transcriptional targets of p53. The PUMA gene encodes two BH3 domain-containing proteins termed PUMA-alpha and PUMA-beta. PUMA proteins bind Bcl-
Synonyms BIRC7; baculoviral IAP repeat containing 7; baculoviral IAP repeat-containing protein 7; KIAP; kidney inhibitor of apoptosis protein; livin; livin inhibitor of apoptosis; melanoma inhibitor of apoptosis protein; ML IAP; mliap; RNF50; RING finger protein 5
    • Species :
    • Human
    • Mouse
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • In Vitro Cell Free System
    • Insect Cell
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human BIRC7-432H Recombinant Human BIRC7, His-tagged E.coli His
    Human BIRC7-636H Recombinant Human BIRC7 Protein, GST-tagged, Active Insect Cell GST
    Human BIRC7-229H Recombinant Human BIRC7, His-tagged E.coli His
    Human BIRC7-231H Recombinant Human BIRC7 Protein, GST-tagged Wheat Germ GST
    Human BIRC7-232H Recombinant Human BIRC7 Protein, GST-tagged Wheat Germ GST
    Human BIRC7-375H Recombinant Human Baculoviral IAP Repeat-containing 7, His-tagged E.coli His
    Mouse BIRC7-2411M Recombinant Mouse BIRC7 Protein Mammalian Cell His
    Zebrafish BIRC7-5722Z Recombinant Zebrafish BIRC7 Mammalian Cell His
    Human BIRC7-8447HCL Recombinant Human BIRC7 293 Cell Lysate HEK293 N/A
    Human BIRC7-8448HCL Recombinant Human BIRC7 293 Cell Lysate HEK293 N/A
    Human BIRC7-1640HF Recombinant Full Length Human BIRC7 Protein, GST-tagged In Vitro Cell Free System GST
    Human BIRC7-2569H Recombinant Human BIRC7 protein, His-tagged E.coli His
    Human BIRC7-301202H Recombinant Human BIRC7 protein, GST-tagged E.coli GST
    Human BIRC7-3679H Recombinant Human BIRC7 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human BIRC7-4174H Recombinant Human BIRC7 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Mouse Birc7-1870M Recombinant Mouse Birc7 Protein, Myc/DDK-tagged HEK293T Myc/DDK

    BIRC7 involved in several pathways and played different roles in them. We selected most pathways BIRC7 participated on our site, such as Ubiquitin mediated proteolysis, Apoptosis, Toxoplasmosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with BIRC7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Ubiquitin mediated proteolysis UBE2NA; UBE2F; PIAS4A; UBE3C; UBE2D1; BRCA1; UBE4B; UBE2I; UBE2G1B; UBE2U
    Toxoplasmosis MAPK11; HLA-DQA2; IKBKB; LAMA4; MAP3K7; PIK3CB; HLA-DOA; PIK3R3; HLA-DMA; H2-AA
    Pathways in cancer FZD1; LAMC1; CCDC6; LAMB4; GNGT2; TCEB1; MECOM; WNT11; PDGFA; NKX3-1
    Small cell lung cancer TRAF1; NFKB1; RARB; PIK3CB; XIAP; NFKBIA; LAMA3; APAF1; CCNE1; AKT2

    BIRC7 has several biochemical functions, for example, cysteine-type endopeptidase inhibitor activity, cysteine-type endopeptidase inhibitor activity involved in apoptotic process, enzyme binding. Some of the functions are cooperated with other proteins, some of the functions could acted by BIRC7 itself. We selected most functions BIRC7 had, and list some proteins which have the same functions with BIRC7. You can find most of the proteins on our site.

    Function Related Protein
    cysteine-type endopeptidase inhibitor activity Cstb; CTLA2B; CST6; PTTG1; CST7; KNG1; CST9L; NGP; CST3; WFDC2
    cysteine-type endopeptidase inhibitor activity involved in apoptotic process TNFSF14; RPS6KA1; VIL1; RPS6KA3; BIRC5; AVP; ARRB1; SERPINB1A; BIRC2; TFAP2B
    enzyme binding CCND1; SNRPD3; HAND2; HNRNPUL1; HDAC3; CAV1; MAP2K7; ARRB2; UGT1A4; HIST1H2AL
    ligase activity RNF38; UBE2IA; RNF126; CBX4; MID2; TTLL9; PET112L; RNF4; DTX4; NEDD4
    protein binding HSFX1; CEACAM6; IGF2; FOXN3; PMP2; RAB7L1; CLPX; ARMCX5-GPRASP2; RTN4RL2A; Apba1
    ubiquitin-protein transferase activity HECTD1; HUWE1; UBE2E2; UBE2S; ARIH2; RNF144AA; TNFAIP3; ARIH1L; MUL1B; TRIM28
    zinc ion binding S100A9; BRF1; SIRT6; HIF1AN; RNF13; ZDHHC15A; LHX8A; NR1D2; SEC23A; EDEM3

    BIRC7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BIRC7 here. Most of them are supplied by our site. Hope this information will be useful for your research of BIRC7.


    Durinck, S; Stawiski, EW; et al. Spectrum of diverse genomic alterations define non-clear cell renal carcinoma. NATURE GENETICS 47:13-+(2015).
    Vital, DAL; de Mejia, EG; et al. Peptides in common bean fractions inhibit human colorectal cancer cells. FOOD CHEMISTRY 157:347-355(2014).

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