BIRC7

  • Official Full Name

    baculoviral IAP repeat containing 7

  • Background

    PUMA (p53 up-regulated modulator of apoptosis) is one of the pro-apoptotic Bcl-2 family members that are also transcriptional targets of p53. The PUMA gene encodes two BH3 domain-containing proteins termed PUMA-alpha and PUMA-beta. PUMA proteins bind Bcl-
  • Synonyms

    BIRC7; baculoviral IAP repeat containing 7; baculoviral IAP repeat-containing protein 7; KIAP; kidney inhibitor of apoptosis protein; livin; livin inhibitor of apoptosis; melanoma inhibitor of apoptosis protein; ML IAP; mliap; RNF50; RING finger protein 5;
    • Type:
    • Cell & Tissue Lysates
    • Recombinant Proteins
    • Protein Pre-coupled Magnetic Beads
    • Species :
    • Human
    • Mouse
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Insect Cell
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • His (Fc)
    • Avi
    • Myc
    • DDK
    • N/A
    • No tag
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human BIRC7-8447HCL Recombinant Human BIRC7 293 Cell Lysate HEK293 N/A
    Human BIRC7-375H Recombinant Human Baculoviral IAP Repeat-containing 7, His-tagged E.coli His
    Human BIRC7-432H Active Recombinant Human BIRC7, His-tagged E.coli His
    Human BIRC7-636H Active Recombinant Human BIRC7 Protein, GST-tagged, Active Insect Cell GST
    Human BIRC7-8448HCL Recombinant Human BIRC7 293 Cell Lysate HEK293 N/A
    Human BIRC7-231H Recombinant Human BIRC7 Protein, GST-tagged Wheat Germ GST
    Human BIRC7-2569H Recombinant Human BIRC7 protein, His-tagged E.coli His
    Human BIRC7-3679H Recombinant Human BIRC7 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human BIRC7-232H Recombinant Human BIRC7 Protein, GST-tagged Wheat Germ GST
    Human BIRC7-301202H Recombinant Human BIRC7 protein, GST-tagged E.coli GST
    Human BIRC7-0092H Recombinant Human BIRC7 Protein (M1-S298), Tag Free E.coli No tag
    Human BIRC7-4174H Recombinant Human BIRC7 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human BIRC7-449H-B Recombinant Human BIRC7 Protein Pre-coupled Magnetic Beads HEK293
    Human BIRC7-449H Recombinant Human BIRC7 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
    Human BIRC7-0093H Recombinant Human BIRC7 Protein (M1-S298), His tagged E.coli His
    Human BIRC7-229H Recombinant Human BIRC7, His-tagged E.coli His
    Mouse BIRC7-1036M-B Recombinant Mouse BIRC7 Protein Pre-coupled Magnetic Beads HEK293
    Mouse BIRC7-1036M Recombinant Mouse BIRC7 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
    Mouse BIRC7-2411M Recombinant Mouse BIRC7 Protein Mammalian Cell His
    Mouse Birc7-1870M Recombinant Mouse Birc7 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Zebrafish BIRC7-5722Z Recombinant Zebrafish BIRC7 Mammalian Cell His
    • Involved Pathway
    • Protein Function
    • Interacting Protein
    • BIRC7 Related Articles
    • BIRC7 Related Research Area

    BIRC7 involved in several pathways and played different roles in them. We selected most pathways BIRC7 participated on our site, such as Ubiquitin mediated proteolysis, Apoptosis, Toxoplasmosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with BIRC7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Ubiquitin mediated proteolysisCDC23;SIAH1;UBE4A;UBE3B;HUWE1;UBE2S;UBOX5;NHLRC1;TRIM37
    ApoptosisMAP3K14;CSF2RB;BIRC8;PRKACBA;DSG1;BCL2L11;CAPN2B;IRF2A;BOK
    ToxoplasmosisTGFB1;HSPA1B;PPIF;IL12B;SOCS1;MAP3K7;BIRC3;IKBKG;NFKB1
    Pathways in cancerGNB4;Ar;NKX3-1;GNB1;PTGER1;PML;FZD10;IKBKG;VEGFB
    Small cell lung cancerLAMA1;MAX;PTGS2;IKBKG;RXRA;BCL2;LAMA2;PIK3R1;TP53

    BIRC7 has several biochemical functions, for example, cysteine-type endopeptidase inhibitor activity, cysteine-type endopeptidase inhibitor activity involved in apoptotic process, enzyme binding. Some of the functions are cooperated with other proteins, some of the functions could acted by BIRC7 itself. We selected most functions BIRC7 had, and list some proteins which have the same functions with BIRC7. You can find most of the proteins on our site.

    Function Related Protein
    cysteine-type endopeptidase inhibitor activityCST2;CST8;CST4;AHSG1;SERPINB13;AHSG2;AHSG;CST6;SERPINB3
    cysteine-type endopeptidase inhibitor activity involved in apoptotic processNAIP1;SNCA;VIL1;RPS6KA1;MT3;NOL3;TFAP2B;XIAP;IGF1RA
    enzyme bindingATF7;UGT1A4;ATXN10;MAP2K7;SCNM1;HAND2;AXIN2;PHB;NOTCH3
    ligase activityZSWIM2;CBX4;PCXA;RNF5;PIAS4;RNF133;ADSSL;RNF139;MARCH5
    protein bindingRNF135;TUBA1B;RRM2B;EN1;ATP6AP2;MED19;IRF4;SOST;KIAA0146
    ubiquitin-protein transferase activityMKRN1;RAG1;FBXO30A;TRIM5;RNF187;TRAF4B;ANAPC4;UBE2O;FBXO7
    zinc ion bindingDPP3;TRIM7;CNOT4B;FHL3B;OTUD7B;RNF26;TRIM42;TRAF2;BTR22

    BIRC7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BIRC7 here. Most of them are supplied by our site. Hope this information will be useful for your research of BIRC7.

    CASP9; DIABLO; POLR1C; PHF1

    Durinck, S; Stawiski, EW; et al. Spectrum of diverse genomic alterations define non-clear cell renal carcinoma. NATURE GENETICS 47:13-+(2015).
    Vital, DAL; de Mejia, EG; et al. Peptides in common bean fractions inhibit human colorectal cancer cells. FOOD CHEMISTRY 157:347-355(2014).
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