BIRC7

  • Official Full Name

    baculoviral IAP repeat containing 7

  • Overview

    PUMA (p53 up-regulated modulator of apoptosis) is one of the pro-apoptotic Bcl-2 family members that are also transcriptional targets of p53. The PUMA gene encodes two BH3 domain-containing proteins termed PUMA-alpha and PUMA-beta. PUMA proteins bind Bcl-
  • Synonyms

    BIRC7; baculoviral IAP repeat containing 7; baculoviral IAP repeat-containing protein 7; KIAP; kidney inhibitor of apoptosis protein; livin; livin inhibitor of apoptosis; melanoma inhibitor of apoptosis protein; ML IAP; mliap; RNF50; RING finger protein 5;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Zebrafish
  • E. coli
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Insect Cell
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • C
  • His
  • Flag
  • GST
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
  • No tag
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human BIRC7-432H Active Recombinant Human BIRC7, His-tagged E.coli His
Human BIRC7-636H Active Recombinant Human BIRC7 Protein, GST-tagged Insect Cell GST
Human BIRC7-232H Recombinant Human BIRC7 Protein, GST-tagged Wheat Germ GST
Human BIRC7-375H Recombinant Human Baculoviral IAP Repeat-containing 7, His-tagged E.coli His
Human BIRC7-229H Active Recombinant Human BIRC7 protein(Met1-Ser298), His-tagged E. coli C-His
Human BIRC7-231H Recombinant Human BIRC7 Protein, GST-tagged Wheat Germ GST
Human BIRC7-8447HCL Recombinant Human BIRC7 293 Cell Lysate HEK293 N/A
Human BIRC7-8448HCL Recombinant Human BIRC7 293 Cell Lysate HEK293 N/A
Human BIRC7-3679H Recombinant Human BIRC7 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human BIRC7-2569H Recombinant Human BIRC7 protein, His-tagged E.coli His
Human BIRC7-301202H Recombinant Human BIRC7 protein, GST-tagged E.coli GST
Human BIRC7-449H-B Recombinant Human BIRC7 Protein Pre-coupled Magnetic Beads HEK293
Human BIRC7-4174H Recombinant Human BIRC7 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human BIRC7-2176HFL Recombinant Full Length Human BIRC7 Protein, C-Flag-tagged Mammalian cells Flag
Human BIRC7-1640HF Recombinant Full Length Human BIRC7 Protein, GST-tagged In Vitro Cell Free System GST
Human BIRC7-0092H Recombinant Human BIRC7 Protein (M1-S298), Tag Free E.coli No tag
Human BIRC7-0093H Recombinant Human BIRC7 Protein (M1-S298), His tagged E.coli His
Human BIRC7-449H Recombinant Human BIRC7 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse BIRC7-2411M Recombinant Mouse BIRC7 Protein Mammalian Cell His
Mouse BIRC7-1036M Recombinant Mouse BIRC7 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse BIRC7-1036M-B Recombinant Mouse BIRC7 Protein Pre-coupled Magnetic Beads HEK293
Mouse Birc7-1870M Recombinant Mouse Birc7 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Zebrafish BIRC7-5722Z Recombinant Zebrafish BIRC7 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • BIRC7 Related Articles
  • BIRC7 Related Research Area

BIRC7 involved in several pathways and played different roles in them. We selected most pathways BIRC7 participated on our site, such as Ubiquitin mediated proteolysis, Apoptosis, Toxoplasmosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with BIRC7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Ubiquitin mediated proteolysisERCC8;FBXW11B;MAP3K1;PIAS4B;UBA3;FZR1A;UBE2G1B;CUL2;PRPF19
ApoptosisDSP;PRKACBB;TRADD;ADD1;NFKBIA;FASLG;BADB;PIK3R2;AKT1
ToxoplasmosisTRAF6;BIRC3;Toxoplasma Gondii Microneme Protein MIC3;TLR2;H2-AA;LAMB3;HLA-DRB1;GNAI2;HSPA1B
Pathways in cancerMAP2K2;MAPK1;EP300;MITF;GNG4;APPL1;SFPI1;MSH6;TPR
Small cell lung cancerLAMB1;ITGA2B;PIAS2;LAMA5;LAMA4;LAMC2;TRAF2;CKS2;ITGAV

BIRC7 has several biochemical functions, for example, cysteine-type endopeptidase inhibitor activity, cysteine-type endopeptidase inhibitor activity involved in apoptotic process, enzyme binding. Some of the functions are cooperated with other proteins, some of the functions could acted by BIRC7 itself. We selected most functions BIRC7 had, and list some proteins which have the same functions with BIRC7. You can find most of the proteins on our site.

Function Related Protein
cysteine-type endopeptidase inhibitor activityHRG;CST5;NAIP1;AHSG;CST14B.1;BIRC5;SERPINB13;CSTA;BIRC7
cysteine-type endopeptidase inhibitor activity involved in apoptotic processNOL3;NAIP1;BIRC3;RPS6KA1;PRDX3;GAS6;TFAP2B;ARRB1;CD27
enzyme bindingZFP36;MDM2;SUDS3;SPDL1;PTEN;MLEC;CRB2;LGALS9;PRKCH
ligase activityPIAS2;MGRN1A;RBBP6;CCNB1IP1;MIB1;HECTD1;RNF170;RNF4;ARIH2
protein bindingSNRNP25;DCP1B;SOCS3;BCL11B;GFI1;ERP27;TRIM74;EBF1;ADAMTS10
ubiquitin-protein transferase activityUBE2O;RNF181;SKP1;UBR4;CNOT4;LTN1;FEM1B;NLRC4;BTR22
zinc ion bindingCXXC4;USP22;CLIP1;TK1;CA15C;TRAF5;MGRN1B;RNF113A;ZMAT2

BIRC7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BIRC7 here. Most of them are supplied by our site. Hope this information will be useful for your research of BIRC7.

CASP9; DIABLO; POLR1C; PHF1

Durinck, S; Stawiski, EW; et al. Spectrum of diverse genomic alterations define non-clear cell renal carcinoma. NATURE GENETICS 47:13-+(2015).
Vital, DAL; de Mejia, EG; et al. Peptides in common bean fractions inhibit human colorectal cancer cells. FOOD CHEMISTRY 157:347-355(2014).
  • Q&As
  • Reviews

Q&As (6)

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How can BIRC7 be used to treat cancer? 09/22/2022

In response to the role of BIRC7 in cancer, some therapeutics can be developed, such as inhibitors or antibodies targeting BIRC7, which are used to inhibit the proliferation and survival of tumor cells and enhance the attack ability of the immune system.

How does BIRC7 correlate with other genes? 09/07/2022

It has complex associations with other genes and may interact with multiple genes to participate in biochemical processes such as apoptosis.

What are the mutation types in BIRC7? 06/22/2022

The types of mutations in BIRC7 include point mutations, insertions/deletions, duplications, etc., which may cause structural and functional abnormalities of the protein.

What is the role of BIRC7 in cancer? 09/04/2021

BIRC7 has a dual role in cancer, on the one hand, it can promote the proliferation and survival of tumor cells, and on the other hand, it can also suppress the immune response and help tumor cells evade the attack of the immune system.

How to study the regulatory mechanism of BIRC7? 12/07/2020

Studying the regulatory mechanism of BIRC7 requires a comprehensive use of various experimental methods and techniques, such as gene knockout, transcriptome analysis, and protein-protein interactions.

Can the expression pattern of BIRC7 be used for disease diagnosis? 09/26/2020

By detecting the expression pattern of BIRC7, it can assist in the diagnosis of certain diseases, such as cancer, neurodegenerative diseases, etc.

Customer Reviews (3)

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Reviews
10/27/2022

    High solubility, fast dissolution, good adaptability to solvents.

    01/09/2022

      BIRC7 has performed well in various experiments and is a reliable choice.

      12/22/2021

        Very suitable for biological activity experiment, good activity.

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