BIRC7 Protein

BIRC7

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BIRC7

Official Full Name baculoviral IAP repeat containing 7
Background PUMA (p53 up-regulated modulator of apoptosis) is one of the pro-apoptotic Bcl-2 family members that are also transcriptional targets of p53. The PUMA gene encodes two BH3 domain-containing proteins termed PUMA-alpha and PUMA-beta. PUMA proteins bind Bcl-
Synonyms BIRC7; baculoviral IAP repeat containing 7; baculoviral IAP repeat-containing protein 7; KIAP; kidney inhibitor of apoptosis protein; livin; livin inhibitor of apoptosis; melanoma inhibitor of apoptosis protein; ML IAP; mliap; RNF50; RING finger protein 5
    • Species :
    • Human
    • Mouse
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Insect Cell
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human BIRC7-2569H Recombinant Human BIRC7 protein, His-tagged E.coli His
    Human BIRC7-301202H Recombinant Human BIRC7 protein, GST-tagged E.coli GST
    Human BIRC7-229H Recombinant Human BIRC7, His-tagged E.coli His
    Human BIRC7-231H Recombinant Human BIRC7 Protein, GST-tagged Wheat Germ GST
    Human BIRC7-232H Recombinant Human BIRC7 Protein, GST-tagged Wheat Germ GST
    Human BIRC7-3679H Recombinant Human BIRC7 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human BIRC7-375H Recombinant Human Baculoviral IAP Repeat-containing 7, His-tagged E.coli His
    Human BIRC7-4174H Recombinant Human BIRC7 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human BIRC7-432H Recombinant Human BIRC7, His-tagged E.coli His
    Human BIRC7-636H Recombinant Human BIRC7 Protein, GST-tagged, Active Insect Cell GST
    Human BIRC7-8447HCL Recombinant Human BIRC7 293 Cell Lysate HEK293 N/A
    Human BIRC7-8448HCL Recombinant Human BIRC7 293 Cell Lysate HEK293 N/A
    Mouse Birc7-1870M Recombinant Mouse Birc7 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Mouse BIRC7-2411M Recombinant Mouse BIRC7 Protein Mammalian Cell His
    Zebrafish BIRC7-5722Z Recombinant Zebrafish BIRC7 Mammalian Cell His

    BIRC7 involved in several pathways and played different roles in them. We selected most pathways BIRC7 participated on our site, such as Ubiquitin mediated proteolysis, Apoptosis, Toxoplasmosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with BIRC7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Ubiquitin mediated proteolysis MGRN1A; ANAPC7; ANAPC1; CBLC; UBOX5; CUL1B; CDH1-A; FZR1A; TRIM32; FBXW7
    Apoptosis PIK3R3B; GZME; CAPN2B; BAX; CLSPN; BIRC5A; PIK3CA; TNFRSF10B; TP53; NFKBIAA
    Toxoplasmosis LAMA5; LAMA2; MAP3K7; PIK3R3; MAPK11; HLA-DMB; HLA-DRB4; AKT1; HLA-DQB1; TGFB1
    Pathways in cancer TP53; ITGAV; RALGDS; XIAP; MAPK9; GNA12; CSF1R; GNG8; RARA; FGF3
    Small cell lung cancer LAMA4; NFKBIA; LAMB4; AKT1; LAMB2; TRAF1; PIAS2; SKP2; COL4A1; RB1

    BIRC7 has several biochemical functions, for example, cysteine-type endopeptidase inhibitor activity, cysteine-type endopeptidase inhibitor activity involved in apoptotic process, enzyme binding. Some of the functions are cooperated with other proteins, some of the functions could acted by BIRC7 itself. We selected most functions BIRC7 had, and list some proteins which have the same functions with BIRC7. You can find most of the proteins on our site.

    Function Related Protein
    cysteine-type endopeptidase inhibitor activity LCN1; CST4; FETUB; CST9; NAIP1; KNG1; CST5; Cstb; AHSG; CST8
    cysteine-type endopeptidase inhibitor activity involved in apoptotic process TNFSF14; IGF1RB; NOL3; BIRC7; DPEP1; PRDX3; RPS6KA1; C1QL4L; NAIP1; SERPINB1A
    enzyme binding GSTM2; MST1R; SUDS3; EIF4E; TUT1; CYB5A; CYP1A1; ANK1; TSPYL1; UGT1A3
    ligase activity NSMCE2; BRCA1; TTLL13; CCNB1IP1; UBE3C; TRIM21; MARCH5; LNX1; PRPF19; MARCH6
    protein binding STX3; ERLIN1; NCOA5; UNC13D; KRTAP4-2; PHIP; ADCK5; TTC3; LARP2; ZNF404
    ubiquitin-protein transferase activity FBXO9; TRIM71; UBE2H; LMO7; BIRC7; RFWD3; UBE2B; UHRF1; FBXO4; FBXL14A
    zinc ion binding NBR1; CAR3; TRAF6; RARGA; FTR14; CA5B; MT1M; NR2E1; GTF2H2; ZRANB2

    BIRC7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BIRC7 here. Most of them are supplied by our site. Hope this information will be useful for your research of BIRC7.

    CASP9; DIABLO; POLR1C; PHF1

    Durinck, S; Stawiski, EW; et al. Spectrum of diverse genomic alterations define non-clear cell renal carcinoma. NATURE GENETICS 47:13-+(2015).
    Vital, DAL; de Mejia, EG; et al. Peptides in common bean fractions inhibit human colorectal cancer cells. FOOD CHEMISTRY 157:347-355(2014).

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