BIRC7-1640HF
Optional Service: Optional requirements on this protein
Product Overview :
Human BIRC7 full-length ORF ( NP_647478.1, 1 a.a. - 298 a.a.) recombinant protein with GST-tag at N-terminal.
Description :
The protein encoded by this gene is a member of the family of inhibitor of apoptosis proteins (IAP) and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Two transcript variants encoding different isoforms have been found for this gene. The two isoforms have different antiapoptotic properties, with isoform alpha protecting cells from apoptosis induced by staurosporine and isoform b protecting cells from apoptosis induced by etoposide.
Source :
In Vitro Cell Free System
Species :
Human
Tag :
GST
Form :
50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.