Recombinant Human BIRC7 protein, His-tagged

• Cat.No.: BIRC7-2569H
• Product Overview: Recombinant Human BIRC7 protein(151-240 aa), fused to His tag, was expressed in E. coli.

Specification

• Source: E. coli
• Species: Human
• Tag: His
• Form: The purified protein was Lyophilized from sterile PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH7.4). 5 % trehalose and 5 % mannitol are added as protectant before lyophilization. The elution buffer contain 300mM imidazole.
• Protein length: 151-240 aa
• AA Sequence: CQFLLRSKGRDFVHSVQETHSQLLG SWDPWEEPEDAAPVAPSVPASGYPE LPTPRREVQSESAQEPGGVSPAQAQ RAWWVLEPPGARDVE
• Purity: 95%, by SDS-PAGE with Coomassie Brilliant Blue staining.
• Storage: Short-term storage: Store at 2-8°C for (1-2 weeks).
  Long-term storage: Aliquot and store at -20°C to -80°C for up to 3 months, buffer containing 50% glycerol is recommended for reconstitution. Avoid repeat freeze-thaw cycles.
• Reconstitution: Reconstitute at 0.25 µg/μl in 200 μl sterile water for short-term storage.
  Reconstitution with 200 μl 50% glycerol solution is recommended for longer term storage.

Gene Information

• Gene Name: BIRC7 baculoviral IAP repeat containing 7 [ Homo sapiens ]
• Official Symbol: BIRC7
• Synonyms: BIRC7; baculoviral IAP repeat containing 7; baculoviral IAP repeat-containing protein 7; KIAP; kidney inhibitor of apoptosis protein; livin; livin inhibitor of apoptosis; melanoma inhibitor of apoptosis protein; ML IAP; mliap; RNF50; RING finger protein 50; LIVIN; MLIAP; ML-IAP
• Gene ID: 79444
• mRNA Refseq: NM_022161
• Protein Refseq: NP_071444
• MIM: 605737
• UniProt ID: Q96CA5

Reviews

10/27/2022

High solubility, fast dissolution, good adaptability to solvents.

01/09/2022

BIRC7 has performed well in various experiments and is a reliable choice.

12/22/2021

Very suitable for biological activity experiment, good activity.

Q&As

How can BIRC7 be used to treat cancer?

In response to the role of BIRC7 in cancer, some therapeutics can be developed, such as inhibitors or antibodies targeting BIRC7, which are used to inhibit the proliferation and survival of tumor cells and enhance the attack ability of the immune system.

How does BIRC7 correlate with other genes?

It has complex associations with other genes and may interact with multiple genes to participate in biochemical processes such as apoptosis.

What are the mutation types in BIRC7?

The types of mutations in BIRC7 include point mutations, insertions/deletions, duplications, etc., which may cause structural and functional abnormalities of the protein.

What is the role of BIRC7 in cancer?

BIRC7 has a dual role in cancer, on the one hand, it can promote the proliferation and survival of tumor cells, and on the other hand, it can also suppress the immune response and help tumor cells evade the attack of the immune system.

How to study the regulatory mechanism of BIRC7?

Studying the regulatory mechanism of BIRC7 requires a comprehensive use of various experimental methods and techniques, such as gene knockout, transcriptome analysis, and protein-protein interactions.

Can the expression pattern of BIRC7 be used for disease diagnosis?

By detecting the expression pattern of BIRC7, it can assist in the diagnosis of certain diseases, such as cancer, neurodegenerative diseases, etc.