Recombinant Human BIRC7 protein, His-tagged

Cat.No. : BIRC7-2569H
Product Overview : Recombinant Human BIRC7 protein(151-240 aa), fused to His tag, was expressed in E. coli.
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Source : E. coli
Species : Human
Tag : His
Form : The purified protein was Lyophilized from sterile PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH7.4). 5 % trehalose and 5 % mannitol are added as protectant before lyophilization. The elution buffer contain 300mM imidazole.
Protein length : 151-240 aa
AA Sequence : CQFLLRSKGRDFVHSVQETHSQLLG SWDPWEEPEDAAPVAPSVPASGYPE LPTPRREVQSESAQEPGGVSPAQAQ RAWWVLEPPGARDVE
Purity : 95%, by SDS-PAGE with Coomassie Brilliant Blue staining.
Storage : Short-term storage: Store at 2-8°C for (1-2 weeks).
Long-term storage: Aliquot and store at -20°C to -80°C for up to 3 months, buffer containing 50% glycerol is recommended for reconstitution. Avoid repeat freeze-thaw cycles.
Reconstitution : Reconstitute at 0.25 µg/μl in 200 μl sterile water for short-term storage.
Reconstitution with 200 μl 50% glycerol solution is recommended for longer term storage.
Gene Name : BIRC7 baculoviral IAP repeat containing 7 [ Homo sapiens ]
Official Symbol : BIRC7
Synonyms : BIRC7; baculoviral IAP repeat containing 7; baculoviral IAP repeat-containing protein 7; KIAP; kidney inhibitor of apoptosis protein; livin; livin inhibitor of apoptosis; melanoma inhibitor of apoptosis protein; ML IAP; mliap; RNF50; RING finger protein 50; LIVIN; MLIAP; ML-IAP;
Gene ID : 79444
mRNA Refseq : NM_022161
Protein Refseq : NP_071444
MIM : 605737
UniProt ID : Q96CA5

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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How can BIRC7 be used to treat cancer? 09/22/2022

In response to the role of BIRC7 in cancer, some therapeutics can be developed, such as inhibitors or antibodies targeting BIRC7, which are used to inhibit the proliferation and survival of tumor cells and enhance the attack ability of the immune system.

How does BIRC7 correlate with other genes? 09/07/2022

It has complex associations with other genes and may interact with multiple genes to participate in biochemical processes such as apoptosis.

What are the mutation types in BIRC7? 06/22/2022

The types of mutations in BIRC7 include point mutations, insertions/deletions, duplications, etc., which may cause structural and functional abnormalities of the protein.

What is the role of BIRC7 in cancer? 09/04/2021

BIRC7 has a dual role in cancer, on the one hand, it can promote the proliferation and survival of tumor cells, and on the other hand, it can also suppress the immune response and help tumor cells evade the attack of the immune system.

How to study the regulatory mechanism of BIRC7? 12/07/2020

Studying the regulatory mechanism of BIRC7 requires a comprehensive use of various experimental methods and techniques, such as gene knockout, transcriptome analysis, and protein-protein interactions.

Can the expression pattern of BIRC7 be used for disease diagnosis? 09/26/2020

By detecting the expression pattern of BIRC7, it can assist in the diagnosis of certain diseases, such as cancer, neurodegenerative diseases, etc.

Customer Reviews (3)

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10/27/2022

    High solubility, fast dissolution, good adaptability to solvents.

    01/09/2022

      BIRC7 has performed well in various experiments and is a reliable choice.

      12/22/2021

        Very suitable for biological activity experiment, good activity.

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