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Official Full Name bone morphogenetic protein 4
Background Bone morphogenetic protein 4 is a protein that in humans is encoded by BMP4 gene. BMP4 is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors.
Synonyms BMP4; bone morphogenetic protein 4; ZYME; BMP2B; OFC11; BMP2B1; MCOPS6; BMP-4; Bone morphogenetic protein 2B; BMP-2B; BMP2B, DVR4; OTTHUMP00000178992
    • Species :
    • Chicken
    • Human
    • Mouse
    • Pig
    • Rabbit
    • Rat
    • Zebrafish
    • Source :
    • CHO
    • E.coli
    • HEK293
    • HeLa
    • Mammalian Cell
    • NS0
    • Tag :
    • Fc
    • GST
    • His
    • His/Myc
    • Myc
    • S
    • T7
    • Met
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human BMP4-001H Recombinant Human BMP4 Protein, His-MBP-tagged E.coli His/Myc
    Human BMP4-02H Recombinant Human BMP4 protein E.coli N/A
    Human BMP4-06H Recombinant Human BMP4 E.coli N/A
    Human BMP4-1325HG GMP Recombinant Human BMP4 protein, Fc-tagged HEK293 Fc
    Human BMP4-135HG GMP Recombinant Human BMP4 Protein NS0 N/A
    Human BMP4-20H Recombinant Human Bone Morphogenetic Protein 4 HeLa N/A
    Human BMP4-213H Recombinant Human BMP4 protein, His/S-tagged E.coli His/S
    Human BMP4-21H Recombinant Human BMP4, His-tagged E.coli His
    Human BMP4-23H Recombinant Human Bone Morphogenetic Protein 4 HEK293 N/A
    Human BMP4-24H Recombinant Human BMP4, HIgG1 Fc-tagged, mutant CHO Fc
    Human BMP4-26171TH Recombinant Human BMP4, His-tagged E.coli His
    Human BMP4-261H Recombinant Human BMP4 protein HeLa N/A
    Human BMP4-262H Recombinant Human BMP4 protein, His-tagged E.coli His
    Human BMP4-263H Recombinant Human BMP4 protein, His-tagged E.coli His
    Human BMP4-266H Recombinant Human BMP4 Protein, GST-tagged E.coli GST
    Human BMP4-569H Recombinant Human BMP4 protein, His & T7-tagged E.coli His/T7
    Human BMP4-8431HCL Recombinant Human BMP4 293 Cell Lysate HEK293 N/A
    Human BMP4-8432HCL Recombinant Human BMP4 293 Cell Lysate HEK293 N/A
    Mouse Bmp4-024MG GMP Recombinant Mouse Bmp4 protein, Fc-tagged HEK293 Fc
    Mouse Bmp4-036M Recombinant Mouse Bmp4 Protein E.coli
    Mouse Bmp4-214M Recombinant Mouse Bmp4 protein, His/S-tagged E.coli His/S
    Mouse BMP4-2432M Recombinant Mouse BMP4 Protein Mammalian Cell His
    Mouse BMP4-267H Recombinant Mouse BMP4 Protein, His-MBP-tagged E.coli His/Myc
    Mouse Bmp4-578TM Recombinant Murine BMP4 E.coli N/A
    Mouse Bmp4-583M Recombinant Mouse BMP-4 E.coli N/A
    Mouse BMP4-869M Recombinant Mouse BMP4 Protein, Fc-tagged HEK293 Fc
    Rat Bmp4-215R Recombinant Rat Bmp4 protein, His/S-tagged E.coli His/S
    Rat Bmp4-572R Recombinant Rat Bmp4 protein, His-tagged E.coli His
    Rat Bmp4-573R Recombinant Rat Bmp4 protein, His-tagged E.coli His
    Chicken BMP4-568C Recombinant Chicken BMP4 protein, His-tagged E.coli His
    Rabbit BMP4-574R Recombinant Rabbit BMP4 protein, His-tagged E.coli His
    Rabbit BMP4-575R Recombinant Rabbit BMP4 protein, His-tagged E.coli His
    Chicken BMP4-6790C Recombinant Chicken BMP4 Mammalian Cell His
    Zebrafish bmp4-809Z Recombinant Zebrafish bmp4 E.coli Met
    Pig BMP4-570P Recombinant Pig BMP4 protein, His-tagged E.coli His
    Pig BMP4-571P Recombinant Pig BMP4 protein, His & GST-tagged E.coli His/GST

    bmp4 involved in several pathways and played different roles in them. We selected most pathways bmp4 participated on our site, such as Hedgehog signaling pathway, TGF-beta signaling pathway, Hippo signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with bmp4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Hedgehog signaling pathway CSNK1DB; GLI2A; SHHA; DHH; GSK3AA; PRKACAB; CSNK1G3; PRKACB; CSNK1G1; DYRK1A
    TGF-beta signaling pathway SMAD2; BMP6; IFNG1-2; ACVR2A; PPP2CB; BAMBI; NOG; RHOAC; RHOAA; RBX1
    Hippo signaling pathway GDF6; NKD1; BMPR1B; PPP1CA; TCF7L2; BMP2; SNAI2; BIRC2; YAP1; WWTR1
    Signaling pathways regulating pluripotency of stem cells ZFHX3; WNT1; WNT5A; ID2; BMI1; AKT1; GSK3B; RAF1; LIF; SOX2
    Thyroid hormone signaling pathway ESR1; SRC; NCOA1; PDPK1; MAPK1; PRKCG; PIK3R2; TP53; HIF1A; SIN3A
    Pathways in cancer Fgf15; TCF7; ARNT; MMP1; FGF22; IL-8; HHIP; LPAR3; WNT2B; GNGT2
    Basal cell carcinoma Fzd4; WNT9A; PTCH1; WNT4; TCF7; WNT9B; BMP2; WNT3A; WNT8B; DVL2

    bmp4 has several biochemical functions, for example, BMP receptor binding, chemoattractant activity, co-receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by bmp4 itself. We selected most functions bmp4 had, and list some proteins which have the same functions with bmp4. You can find most of the proteins on our site.

    Function Related Protein
    BMP receptor binding BMP7B; BMP6; BMP3; BMP2; PYCARD; BMP5; BMP2B; BMP7; BMP8A; BMP7A
    chemoattractant activity FGF2; CCL15; NTF3; FGF8; CXCL12; SAA1; HMGB1; PDGFB; SCG2; HGF
    co-receptor binding BMP2; DKK1; NEO1; HFE; BMP4; TFR2
    cytokine activity BMP8B; CSF1B; Ctf2; WNT5A; CMTM6; IL17A/F3; IL17A; CCL6; GRN; IL5
    growth factor activity FGF8; KLK1B3; VEGFAA; PDGFC; HDGF; FBRS; REG1A; GSDF; BMP15; BMP2
    heparin binding NAV2; PCOLCE; SERPINA5; LIPH; PLA2G2D; FGF2; CCDC80; F11; COL13A1; WISP1A
    protein binding CDAN1; NUP107; HIST1H2AH; MAGEA6; MFF; SHARPIN; KRTAP9-4; RAB34; VAMP7; PRMT1
    protein homodimerization activity KYNU; TPR; COMMD1; GCH1; NPM1; ACOT7; GDF6; ACHE; PML; PRTFDC1
    transforming growth factor beta receptor binding AMH; MSTNA; GDF3; INHBA; LFT2; GDF1; GDF2; TGFBRAP1; GDF5; BMP3

    bmp4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with bmp4 here. Most of them are supplied by our site. Hope this information will be useful for your research of bmp4.

    BMPR1A; FSTL1; WFIKKN2; WFIKKN1; olfml3; chrd; ZFYVE9; C12orf60

    Arany, PR; Huang, GX; et al. Multi-lineage MSC Differentiation via Engineered Morphogen Fields. JOURNAL OF DENTAL RESEARCH 93:1250-1257(2014).
    Siddique, I; Curran, SP; et al. Gremlin Promotes Peritoneal Membrane Injury in an Experimental Mouse Model and Is Associated with Increased Solute Transport in Peritoneal Dialysis Patients. AMERICAN JOURNAL OF PATHOLOGY 184:2976-2984(2014).


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