Active Recombinant Human BMP4
Cat.No. : | BMP4-06H |
Product Overview : | This E.coli derived BMP-4 is a fully active homodimeric protein consisting of two 106 amino acid subunits which correspond to amino acids 303-408 of the full length BMP-4 precursor. Manufactured using all non-animal reagents. |
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Description : | Bone morphogenetic proteins (BMPs) constitute a subfamily within the TGF-β superfamily of structurally related signaling proteins. Members of this superfamily are widely distributed throughout the body and are involved in diverse physiological processes during both pre- and postnatal life. Like BMP-7, BMP-4 is involved in the development and maintenance of bone and cartilage. Reduced expression of BMP-4 is associated with a number of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. |
Source : | E. coli |
Species : | Human |
Bio-activity : | Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells. The expected ED50 for this effect is 5-10 ng/ml. |
AA Sequence : | KKNKNCRRHS LYVDFSDVGW NDWIVAPPGY QAFYCHGDCP FPLADHLNST NHAIVQTLVN SVNSSIPKAC CVPTELSAIS MLYLDEYDKV VLKNYQEMVV EGCGCR |
Purity : | Greater than 98% by SDS-PAGE gel and HPLC analyses. |
Storage : | Store at -20°C. Avoid repeated freeze-thaw cycles. |
Gene Name : | BMP4 bone morphogenetic protein 4 [ Homo sapiens ] |
Official Symbol : | BMP4 |
Synonyms : | BMP4; bone morphogenetic protein 4; BMP2B; BMP-4; BMP-2B; bone morphogenetic protein 2B; ZYME; OFC11; BMP2B1; MCOPS6; |
Gene ID : | 652 |
mRNA Refseq : | NM_001202 |
Protein Refseq : | NP_001193 |
MIM : | 112262 |
UniProt ID : | P12644 |
Chromosome Location : | 14q22-q23 |
Pathway : | Adipogenesis, organism-specific biosystem; Basal cell carcinoma, organism-specific biosystem; Basal cell carcinoma, conserved biosystem; Glypican 3 network, organism-specific biosystem; Heart Development, organism-specific biosystem; Hedgehog signaling pathway, organism-specific biosystem; Hedgehog signaling pathway, conserved biosystem; |
Function : | BMP receptor binding; chemoattractant activity; cytokine activity; growth factor activity; protein binding; |
Products Types
◆ Recombinant Protein | ||
Bmp4-036M | Active Recombinant Mouse Bmp4 Protein | +Inquiry |
Bmp4-324M | Recombinant Mouse Bmp4 Protein, His-tagged | +Inquiry |
BMP4-013H | Active Recombinant Human BMP4 Protein | +Inquiry |
Bmp4-15M | Active Recombinant Mouse Bmp4 Protein (Lys303-Arg408), C-His tagged, Animal-free, Carrier-free | +Inquiry |
BMP4-321H | Recombinant Human BMP4 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
BMP4-8432HCL | Recombinant Human BMP4 293 Cell Lysate | +Inquiry |
BMP4-8431HCL | Recombinant Human BMP4 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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