Recombinant Human BMP4 Protein, His-MBP-tagged
Cat.No. : | BMP4-001H |
Product Overview : | Recombinant Human BMP4 Protein 25-408 aa (full-length) with His-MBP tag was expressed in E.coli. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates heart development and adipogenesis. Mutations in this gene are associated with orofacial cleft and microphthalmia in human patients. The encoded protein may also be involved in the pathology of multiple cardiovascular diseases and human cancers. |
Source : | E. coli |
Species : | Human |
Tag : | His-MBP |
Molecular Mass : | 90.2 kDa |
Purity : | >90% confirmed by 10% SDS-PAGE stained with Coomassie Blue (CB) |
Applications : | ELISA, WB, Antibody Production, Protein array |
Quality Control Test : | 10% SDS-PAGE stained with Coomassie Blue (CB), immunobloting with anti-MBP (WB) and peptide fingerprinting by MALDI-TOF mass spectrometry. |
Storage : | Store working aliquots at 4 centigrade for up to one week. For extended storage, conserve at −80 centigrade. |
Expiry : | 12 months from the date of purchase, if it is properly stored. |
Storage Buffer : | 20mM Sodium Phosphate, 0.5M NaCl, 0.15M imidazole and 30% glycerol, pH 7.4. No preservatives added. |
Shipping : | Dry Ice |
Gene Name : | BMP4 bone morphogenetic protein 4 [ Homo sapiens (human) ] |
Official Symbol : | BMP4 |
Synonyms : | BMP4; bone morphogenetic protein 4; ZYME; BMP2B; OFC11; BMP2B1; MCOPS6; bone morphogenetic protein 4; bone morphogenetic protein 2B |
Gene ID : | 652 |
mRNA Refseq : | NM_001202 |
Protein Refseq : | NP_001193 |
MIM : | 112262 |
UniProt ID : | P12644 |
Products Types
◆ Lysates | ||
BMP4-8431HCL | Recombinant Human BMP4 293 Cell Lysate | +Inquiry |
BMP4-8432HCL | Recombinant Human BMP4 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionBMP4 can be used in spinal fusion surgery to stimulate bone growth and fuse vertebrae together, which can alleviate back pain and stabilize the spine.
Mutations in BMP4 or its receptors can lead to congenital disorders, such as orofacial clefts and heart defects.
Yes, there are ongoing trials exploring the use of BMP4 in regenerative medicine for conditions like osteoarthritis and tendon injuries.
Yes, some risks include excessive bone growth, swelling, and inflammation at the application site. These complications can be carefully managed by healthcare providers.
Yes, BMP4 can be used to aid in tissue regeneration in cosmetic procedures, such as in the reconstruction of facial bone defects or enhancement of soft tissue volume.
Customer Reviews (3)
Write a reviewThe BMP4 protein is a valuable resource for researchers due to its high quality and its ability to meet specific experimental needs.
the manufacturer's technical support team can offer prompt assistance in case any issues arise during the handling or application of the BMP4 protein.
The manufacturer's support can play a crucial role in assisting researchers throughout their trials.
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