Recombinant Human BMP4 Protein


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Recombinant Human BMP4 Protein

BMP4 Related Products

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Cat.No. : BMP4-03H
Product Overview : Recombinant BMP-4 (293-408 aa) protein without tag was expressed as insoluble protein aggregate in E. coli and purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.
Description : This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates heart development and adipogenesis. Mutations in this gene are associated with orofacial cleft and microphthalmia in human patients. The encoded protein may also be involved in the pathology of multiple cardiovascular diseases and human cancers.
Source : E. coli
Species : Human
Form : Liquid
Molecular Mass : 13.2 kDa
Protein length : 117 aa
Endotoxin : < 1 EU/μg of protein (determined by LAL method)
Purity : > 85% by SDS-PAGE
Applications : SDS-PAGE
Storage : Can be stored at +2 to +8 centigrade for 1 week. For long term storage, aliquot and store at -20 to -80 centigrade. Avoid repeated freezing and thawing cycles.
Concentration : 0.5 mg/mL (determined by Bradford assay)
Storage Buffer : 10 mM Sodium Citrate buffer (pH 3.5) containing 10% glycerol

3 μg by SDS-PAGE under reducing condition and visualized by coomassie blue stain.

Gene Name : BMP4 bone morphogenetic protein 4 [ Homo sapiens (human) ]
Official Symbol : BMP4
Synonyms : BMP4; bone morphogenetic protein 4; ZYME; BMP2B; OFC11; BMP2B1; MCOPS6; bone morphogenetic protein 4; bone morphogenetic protein 2B
Gene ID : 652
mRNA Refseq : NM_001202
Protein Refseq : NP_001193
MIM : 112262
UniProt ID : P12644
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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