Recombinant Human BMP4 Protein, GST-tagged

• Cat.No.: BMP4-266H
• Product Overview: Human BMP4 (NP_001193.1, 25 a.a. - 408 a.a.) partial recombinant protein with His-MBP tag expressed in Escherichia coli.

Specification

• Description: The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. This particular family member plays an important role in the onset of endochondral bone formation in humans, and a reduction in expression has been associated with a variety of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Alternative splicing in the 5 untranslated region of this gene has been described and three variants are described, all encoding an identical protein.
• Source: E. coli
• Species: Human
• Tag: GST
• Form: In 20 mM sodium phosphate, 0.5 M NaCl, 0,5 M imidazole, pH 7.4. (30% glycerol)
• Molecular Mass: 90.266 kDa
• Endotoxin: < 0.1 EU per ug of the protein
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: In 20 mM sodium phosphate, 0.5 M NaCl, 0,5 M imidazole, pH 7.4. (30% glycerol)

Gene Information

• Gene Name: BMP4 bone morphogenetic protein 4 [ Homo sapiens ]
• Official Symbol: BMP4
• Synonyms: BMP4; bone morphogenetic protein 4; BMP2B; BMP-4; BMP-2B; bone morphogenetic protein 2B; ZYME; OFC11; BMP2B1; MCOPS6
• Gene ID: 652
• mRNA Refseq: NM_001202
• Protein Refseq: NP_001193
• MIM: 112262
• UniProt ID: P12644