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Recombinant Mouse Car14 Protein (Ala16-Met290), N-His tagged

Cat.No. : Car14-6725M
Product Overview : Recombinant mouse Ca14 (Ala16-Met290) fused with the N-terminal His tag was expressed in E. coli.
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Description : Enables carbonate dehydratase activity. Predicted to be involved in one-carbon metabolic process. Predicted to act upstream of or within carbon dioxide transport and regulation of pH. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including central nervous system; cranium; epiblast; eye; and urinary system. Orthologous to human CA14 (carbonic anhydrase 14).
Source : E. coli
Species : Mouse
Tag : His
Form : Lyophilized powder/frozen liquid
Molecular Mass : 30.25 kDa
Protein length : Ala16-Met290
Purity : > 90 % as determined by SDS-PAGE
Notes : For research use only.
Storage : Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt.
Storage Buffer : Supplied as solution form in PBS or lyophilized from PBS.
Reconstitution : Reconstitute in sterile water for a stock solution.
Shipping : They are shipped out with dry ice/blue ice unless customers require otherwise.
Gene Name : Car14 carbonic anhydrase 14 [ Mus musculus (house mouse) ]
Official Symbol : Car14
Synonyms : Car14; carbonic anhydrase 14; Ca14; CA-XIV; carbonic anhydrase 14; CA XIV; carbonate dehydratase XIV; carbonic anhydrase XIV; EC 4.2.1.1
Gene ID : 23831
mRNA Refseq : NM_011797
Protein Refseq : NP_035927
UniProt ID : Q9WVT6

Not For Human Consumption!

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Customer Reviews (3)

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Reviews
08/19/2022

    Reliable source, ensures reproducibility in our research.

    11/10/2020

      Efficient services, optimize our protein-related studies.

      10/01/2020

        Responsive customer support, aids in problem-solving effectively.

        Q&As (7)

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        Are there any known small molecule modulators specific to CA14's activity? 10/16/2022

        Specific modulators can be identified through high-throughput screening assays targeting CA14 and validated using in vitro and in vivo models.

        What unique functional attributes differentiate CA14 from other carbonic anhydrase isoforms? 02/14/2022

        CA14's unique functional attributes can be discerned using comparative enzymatic assays and structural analyses against other isoforms.

        How do changes in cellular pH or ion concentrations influence CA14 activity? 09/26/2020

        Influence of pH or ions on CA14 can be analyzed using enzymatic assays under varying conditions and ion-sensitive probes.

        Are there any known disease associations where CA14 mutations or dysregulation play a pivotal role? 05/02/2020

        Disease associations can be determined through genetic studies, patient tissue analyses, and literature reviews focusing on CA14's relevance in pathological conditions.

        In what tissues or cell types is CA14 predominantly expressed, and how does this correlate with its physiological role? 09/17/2019

        Predominant tissue or cell-type expression can be determined using tissue microarrays, qPCR, or proteomic databases, correlating findings with potential physiological implications.

        What are the consequences of CA14 overexpression or knockdown in cellular and organismal models? 02/16/2018

        Consequences of overexpression or knockdown can be assessed using phenotypic analyses, cellular viability assays, and in vivo studies in organisms with altered CA14 expression.

        Are there specific cellular pathways where CA14 plays a crucial modulatory role? 07/15/2017

        CA14's role in cellular pathways can be explored using pathway enrichment analyses, proteomic studies, and pathway-specific assays in CA14-modified cells.

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