Recombinant Swine Chemokine (C-C motif) Ligand 4 CCL4-146S

Recombinant Swine Chemokine (C-C motif) Ligand 4

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Cat.No. : CCL4-146S Optional Service: Optional requirements on this protein
Product Overview : Recombinant Swine CCL4 protein was expressed inYeastand purified by using Ion-exchange chromatography, 7.8 kDa (69 aa).
Description : CCL4 is a CC chemokine with specificity for CCR5 receptors. It is a chemoattractant for natural killer cells, monocytes and a variety of other immune cells. CCL4 is a major HIV-suppressive factor produced by CD8+ T cells. Perforin-low memory CD8+ T cells that normally synthesize MIP-1-beta.
Source : Yeast.
Sequences Of Amino Acids : APMGSDPPTS CCFTYTVRKL PRNFVTDYYE TSSLCSQPAV VFQTKKGRQV CANPSDDWVQ EYMDDLELN.
Formulation/Reconstitution : Lyophilized. Reconstitute with sterile phosphate-buffered saline containing at least 0.1% carrier protein.
Purity : >95% as visualized by SDS-PAGE analysis.
Purification : Ion-exchange chromatography.
Biological Activity : The biological activity of recombinant swine CCL4 was determined in a chemotaxis assay using a Boyden chamber with freshly isolated swine PBMC monocytes using a Percoll gradient enrichment method. Biological activity typically peaks at 10 ng/mL.
Storage : Stable for up to twelve months from date of receipt at -20°C. Stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. Avoid repeated freeze/thaw cycles.
Pathways : Chemokine signaling pathway; Cytokine-cytokine receptor interaction; Cytosolic DNA-sensing pathway
PDB rendering based on 1hum :

Gene Name : CCL4 chemokine (C-C motif) ligand 4 [ Sus scrofa ]
Synonyms : CCL4; chemokine (C-C motif) ligand 4; MIP1b; SCY4A; MIP-1BETA; MIP-1-beta; C-C motif chemokine 4; small-inducible cytokine A4; macrophage inflammatory protein 1-beta
Gene ID : 396668
mRNA Refseq : NM_213779
Protein Refseq : NP_998944
UniProt ID : Q711P4
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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