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Active Recombinant Human Chemokine (C-C Motif) Ligand 4, MIgG2a Fc-tagged
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Cat.No. : | CCL4-119H Optional Service: Optional requirements on this protein |
Product Overview : | The extracellular domain of human CCL4 (AAI04227.1) (Ala24-Asn92) is fused to the N-terminus of the Fc region of mouse IgG2a was expressed in CHO celL |
Description : | The protein encoded by this gene is a mitogen-inducible monokine and is one of the major HIV-suppressive factors produced by CD8+ T-cells. The encoded protein is secreted and has chemokinetic and inflammatory functions. |
Source : | CHO cells |
Species : | Human |
Tag : | MIgG2a Fc-tagged |
Form : | Lyophilized from 0.2μm-filtered solution in PBS. |
Bio-activity : | Measured by its ability to chemoattract BaF3 mouse pro-B cells transfected with human CCR5. |
Molecular Mass : | 34 KDa (monomer) |
AA Sequence : | Ala24-Asn92 |
Endotoxin : | <0.06 eu/μg as determined by lal test.>0.06> |
Purity : | >98%, by SDS-PAGE under reducing conditions. |
Stability : | Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C. |
Reconstitution : | Reconstitute at 100μg/ml in sterile PBS. |
Warning : | Avoid freeze/thaw cycles. |
Gene Name : | CCL4 chemokine (C-C motif) ligand 4 [ Homo sapiens ] |
Official Symbol : | CCL4 |
Synonyms : | CCL4; chemokine (C-C motif) ligand 4; LAG1, SCYA4, small inducible cytokine A4 (homologous to mouse Mip 1b); C-C motif chemokine 4; Act 2; AT744.1; MIP 1 beta; PAT 744; SIS-gamma; MIP-1-beta(1-69); CC chemokine ligand 4; secreted protein G-26; T-cell activation protein 2; small-inducible cytokine A4; lymphocyte-activation gene 1; G-26 T-lymphocyte-secreted protein; lymphocyte activation gene 1 protein; macrophage inflammatory protein 1-beta; small inducible cytokine A4 (homologous to mouse Mip-1b); ACT2; G-26; HC21; LAG1; LAG-1; MIP1B; SCYA2; SCYA4; MIP1B1; MIP-1-beta; MGC104418; MGC126025; MGC126026; |
Gene ID : | 6351 |
mRNA Refseq : | NM_002984 |
Protein Refseq : | NP_002975 |
MIM : | 182284 |
UniProt ID : | P13236 |
Chromosome Location : | 17q21-q23 |
Pathway : | Chemokine receptors bind chemokines, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Cytosolic DNA-sensing pathway, organism-specific biosystem; |
Function : | CCR1 chemokine receptor binding; CCR5 chemokine receptor binding; chemokine activity; cytokine activity; |
◆ Recombinant Protein
CCL4-25H | Recombinant Human CCL4 Protein | +Inquiry |
CCL4-2150H | Recombinant Human CCL4 Protein, His-tagged | +Inquiry |
CCL4-329C | Recombinant Human CCL4 Protein (69 aa) | +Inquiry |
Ccl4-2038M | Recombinant Mouse Ccl4 Protein | +Inquiry |
CCL4-0640H | Recombinant Human CCL4 Protein, GST-Tagged | +Inquiry |
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◆ Lysates
CCL4-7721HCL | Recombinant Human CCL4 293 Cell Lysate | +Inquiry |
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CCL1CCL11Ccl12CCL13CCL14CCL15CCL16CCL17CCL18CCL19CCL2CCL20CCL21Ccl21cCCL22CCL23CCL24CCL25CCL26CCL27Ccl27aCCL28CCL3CCL3L1Ccl4CCL5Ccl6CCL7CCL8Ccl9CCL4L2Ccl21aCCL4L1CCL3L3Ccl21bCcl27b
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