CCR9

  • Official Full Name

    Chemokine (C-C Motif) Receptor 9

  • Overview

    C-C chemokine receptor type 9, also called GPR-9-6 or CDw199, is a protein that in humans is encoded by the CCR9 gene. The protein encoded by this gene is a member of the beta chemoking receptor family. By radiation hybrid analysis and organization of BAC contigs by FISH on combed genomic DNA, the CCR9 gene within the CCR cluster was localized at 3p21.3. It is the receptor for chemokine SCYA25/TECK. This gene subsequently transduces a signal by increasing the intracellular calcium ions level. It is an alternative coreceptor with CD4 for HIV-1 infection. This gene may play a role in the thymocytes recruitment and development that may permit functional specialization of immune responses in different segment of the gastrointestinal tract
  • Synonyms

    C-C chemokine receptor type 9; GPR-9-6; CDw199; AI464239, CCR10, CCR9, Ccbp2, Cmkbr9, D6, CC-CKR-9, CDw199, GPR-9-6, GPR28, A130091K22Rik, Cmkbr10; Chemokine (C-C Motif) Receptor 9;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Assay Kits
  • Chicken
  • Cynomolgus Monkey
  • Homo sapiens (Human)
  • Human
  • Mus musculus (Mouse)
  • Ovis aries (Sheep)
  • E.coli
  • E.coli expression system
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • C
  • hFc
  • His
  • His (Fc)
  • Avi
  • Flag
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CCR9-0699H Recombinant Human CCR9 Protein Wheat Germ N/A
Human CCR9-716H Recombinant Human CCR9 Mammalian Cell His
Human CCR9-310HCL Recombinant Human CCR9 cell lysate N/A
Human CCR9-1079HFL Recombinant Human CCR9 protein, His&Flag-tagged HEK293 His&Flag
Human CCR9-2621H Recombinant Human CCR9 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human CCR9-3960H Recombinant Human CCR9 protein, His-tagged E.coli His
Human CCR9-2621H-B Recombinant Human CCR9 Protein Pre-coupled Magnetic Beads HEK293
Human CCR9-3032HF Recombinant Full Length Human CCR9 Protein In Vitro Cell Free System
Human CCR9-16H Recombinant Human Full Length CCR9 protein, His-tagged(VLPs) HEK293 His
Human CCR9-1371H Active Recombinant Human CCR9 Full Length Transmembrane protein(Nanodisc) HEK293 N/A
Human CCR9-04H Recombinant Human CCR9 Protein, C-hFc-tagged HEK293 C-hFc
Cynomolgus Monkey CCR9-381C Recombinant Cynomolgus CCR9 Protein, His-tagged Mammalian Cell His
Cynomolgus Monkey CCR9-129C-B Recombinant Cynomolgus Monkey CCR9 Protein Pre-coupled Magnetic Beads HEK293
Cynomolgus Monkey CCR9-129C Recombinant Cynomolgus Monkey CCR9 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Homo sapiens (Human) RFL15889HF Recombinant Full Length Human C-C Chemokine Receptor Type 9(Ccr9) Protein, His-Tagged E.coli expression system His
Mus musculus (Mouse) RFL35509MF Recombinant Full Length Mouse C-C Chemokine Receptor Type 9(Ccr9) Protein, His-Tagged E.coli expression system His
Ovis aries (Sheep) RFL4006OF Recombinant Full Length Sheep C-C Chemokine Receptor Type 9(Ccr9) Protein, His-Tagged E.coli expression system His
Chicken CCR9-3499C Recombinant Chicken CCR9 Mammalian Cell His
Kit-0936 CYP2C9 Red Screening Kit N/A
Kit-1163 CCR9 CHO-K1 β-Arrestin GPCR Assay Kit N/A
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • CCR9 Related Articles
  • CCR9 Related Gene Family
  • CCR9 Related Research Area

CCR9 involved in several pathways and played different roles in them. We selected most pathways CCR9 participated on our site, such as Chemokine receptors bind chemokines, Chemokine signaling pathway, Class A/1 (Rhodopsin-like receptors), which may be useful for your reference. Also, other proteins which involved in the same pathway with CCR9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Chemokine receptors bind chemokinesAMCF-II;ACKR4;CCR9;CCR6;CXCL13;CCL35.1;CCL19A.2;CCR5;CCR7
Chemokine signaling pathwayXCR1;PIK3CG;CCR5;KRAS;XCL1;CXCL13;Ccl12;GM13304;ELMO1
Class A/1 (Rhodopsin-like receptors)GPR65;QRFP;AMCF-II;OPN5;PNOCB;ADORA2A;NMU;PENK;CCR3
Cytokine-cytokine receptor interactionNT5C3;THPO;IL11RA2;KIT;IL13;CCL20;CXCR4;ACVR1L;IFNA5
G alpha (i) signalling eventsANXA1A;OPN5;SSTR3;NMUR1;CCL27;NMU;CCR6;CCL19A.2;OPN1LW
GPCR downstream signalingADM2;OPN1LW;PROKR1;CALCB;CALCA;RAMP2;RGR;KISS1;CHRM5
GPCR ligand bindingOXGR1A.1;CCL19A.2;FZD10;SETD6;AMCF-II;TAC2;GPR77;GPRC6A;EDN3
GPCRs, Class A Rhodopsin-likeCHRM4;GPR4;CCRL2;AGTR2;OPN4;GPR65;SSTR3;SSTR5;RRH

CCR9 has several biochemical functions, for example, C-C chemokine receptor activity, chemokine receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CCR9 itself. We selected most functions CCR9 had, and list some proteins which have the same functions with CCR9. You can find most of the proteins on our site.

Function Related Protein
C-C chemokine receptor activityCCR6;CCR5;GPR75;CCR8;CCR9;CCR1;CCBP2;CCR1L1;CCR10
chemokine receptor activityCXCR3;ACKR4;CXCR7B;CCR12A;CCR6;CMKLR1;CXCR3.1;CXCR3.2;XCR1

CCR9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CCR9 here. Most of them are supplied by our site. Hope this information will be useful for your research of CCR9.

Bakdash, G; Vogelpoel, LTC; et al. Retinoic acid primes human dendritic cells to induce gut-homing, IL-10-producing regulatory T cells. MUCOSAL IMMUNOLOGY 8:265-278(2015).
Danese, S; Panes, J; et al. Development of Drugs to Target Interactions Between Leukocytes and Endothelial Cells and Treatment Algorithms for Inflammatory Bowel Diseases. GASTROENTEROLOGY 147:981-989(2014).
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