Active Recombinant Human CD40LG Protein (116-261), N-FLAG tagged, Certified Serum Grade
Cat.No. : | CD40LG-12H |
Product Overview : | Recombinant crtified Serum Grade human CD40L (aa 116-261) fused at the N-terminus to mouse ACRP30headless (aa 18-111) and a FLAG®-tag was expressed in CHO. Certified Serum Grade: Produced using certified high-quality FBS grade serum. Specifications of FBS include Traceability/Source, Sterile Filtered, Virus, Mycoplasma & Endotoxin Tested, Osmolality and Cell Culture Tested, Inactivation by γ-Irradiation. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is expressed on the surface of T cells. It regulates B cell function by engaging CD40 on the B cell surface. A defect in this gene results in an inability to undergo immunoglobulin class switch and is associated with hyper-IgM syndrome. |
Source : | CHO |
Species : | Human |
Tag : | N-FLAG |
Form : | Lyophilized |
Bio-activity : | Induces B cells activation (as demonstrated by dose-dependent upregulation of CD86) (ED50: < 1 ng/mL). B cell expansion online protocol available. |
Molecular Mass : | ~35-40 kDa (SDS-PAGE) |
Protein Length : | 116-261 |
Endotoxin : | < 0.01 EU/μg purified protein (LAL test, Lonza). |
Purity : | ≥95 % (SDS-PAGE) |
Stability : | Stable for at least 6 months after receipt when stored at -20 centigrade. Working aliquots are stable for up to 3 months when stored at -20 centigrade. |
Storage : | Short Term Storage: -20 centigrade Long Term Storage: -20 centigrade |
Concentration : | 1 mg/mL |
Storage Buffer : | Contains PBS |
Handling : | Avoid freeze/thaw cycles. PBS containing at least 0.1 % BSA should be used for further dilutions. |
Shipping : | DRY ICE |
Gene Name : | CD40LG CD40 ligand [ Homo sapiens (human) ] |
Official Symbol : | CD40LG |
Synonyms : | CD40LG; CD40 ligand; IGM; IMD3; TRAP; gp39; CD154; CD40L; HIGM1; T-BAM; TNFSF5; hCD40L; CD40 ligand; CD40 antigen ligand; CD40-L; T-B cell-activating molecule; T-cell antigen Gp39; TNF-related activation protein; tumor necrosis factor (ligand) superfamily member 5 |
Gene ID : | 959 |
mRNA Refseq : | NM_000074 |
Protein Refseq : | NP_000065 |
MIM : | 300386 |
UniProt ID : | P29965 |
Products Types
◆ Recombinant Protein | ||
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CD40LG-682H | Recombinant Human CD40LG Protein, His-tagged | +Inquiry |
Cd40lg-2063M | Active Recombinant Mouse Cd40lg Protein | +Inquiry |
CD40LG-680R | Recombinant Rhesus monkey CD40LG Protein, His-tagged | +Inquiry |
CD40LG-197H | Recombinant Human CD40LG Protein, C-His-tagged | +Inquiry |
◆ Lysates | ||
CD40LG-1205RCL | Recombinant Rat CD40LG cell lysate | +Inquiry |
CD40LG-1080CCL | Recombinant Cynomolgus CD40LG cell lysate | +Inquiry |
CD40LG-001CCL | Recombinant Canine CD40LG cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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