| Description : |
Predicted to enable CD40 receptor binding activity and integrin binding activity. Involved in isotype switching. Acts upstream of or within B cell differentiation and regulation of immunoglobulin production. Located in external side of plasma membrane. Is expressed in Meckel's cartilage; dorsal root ganglion; and limb. Used to study inflammatory bowel disease and systemic lupus erythematosus. Human ortholog(s) of this gene implicated in several diseases, including Kawasaki disease; artery disease (multiple); autoimmune disease (multiple); combined T cell and B cell immunodeficiency (multiple); and hematologic cancer (multiple). Orthologous to human CD40LG (CD40 ligand). |
| Source : |
HEK293 |
| Species : |
Mouse |
| Tag : |
Fc |
| Form : |
Lyophilized |
| Molecular Mass : |
42.9 kDa |
| Protein Length : |
260 |
| AA Sequence : |
MIETYSQPSPRSVATGLPASMKIFM YLLTVFLITQMIGSVLFAVYLHRRL DKVEEEVNLHEDFVFIKKLKRCNKG EGSLSLLNCEEMRRQFEDLVKDITL NKEEKKENSFEMQRGDEDPQIAAHV VSEANSNAASVLQWAKKGYYTMKSN LVMLENGKQLTVKREGLYYVYTQVT FCSNREPSSQRPFIVGLWLKPSSGS ERILLKAANTHSSSQLCEQQSVHLG GVFELQAGASVFVNVTEASQVIHRV GFSSFGLLKL |
| Purity : |
> 98% |
| Applications : |
WB; ELISA; FACS; FC |
| Stability : |
This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use. |
| Storage : |
At -20 centigrade. |
| Concentration : |
1 mg/mL |
| Storage Buffer : |
PBS (pH 7.4-7.5). Sterile-filtered colorless solution. |
| Reconstitution : |
Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance. |
