Recombinant Human CD40LG Protein, Tag Free
Cat.No. : | CD40LG-30H |
Product Overview : | The Human CD40 Ligand yeast-derived recombinant protein is not tagged and is naturally endotoxin-free. |
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Species : | Human |
Source : | Yeast |
Tag : | Non |
Description : | CD40 Ligand (CD40LG) is a transmembrane protein that is a member of the TNF superfamily. In addition to existing in a membrane bound form, CD40LG can also be released as a soluble molecule (sCD40LG), which has been shown to have biological functions. CD40 interacts with CD40 ligand, which is predominantly expressed on activated CD4+ T-cells. CD40LG is transiently expressed on activated T-cells and plays a crucial role in B-cell function. Activated T-cells expressing CD40LG can also interact with CD40 on endothelial cells to induce production of inflammatory cytokines. The transient expression of CD40LG allows T-cells to stimulate selected CD40-bearing cells to participate in the immune response. Increased levels of sCD40LG have been measured in patients with SLE, RA, inflammatory bowel diseases, systemic sclerosis, and Sjogren's syndrome. |
AASequence : | MQKGDQNPQIAAHVISEASSKTTSVLQWAEKGYYTMSNNLVTLENGKQLTVKRQGLYYIYAQVTFCSNREASSQAPFIASLCLKSPGRFERILLRAANTHSSAKPCGQQSIHLGGVFELQPGASVFVNVTDPSQVSHGTGFTSFGLLKL |
Molecular Mass : | 16.2 kDa |
Endotoxin : | Naturally endotoxin-free |
Purity : | Greater than 98% as visualized by SDS-PAGE analysis. |
Application : | Cell Culture, ELISA Standard, ELISpot Control, Western Blot Control |
Note : | For research use only. |
Storage : | At -20 centigrade |
Gene Name | CD40LG CD40 ligand [ Homo sapiens (human) ] |
Official Symbol | CD40LG |
Synonyms | CD40LG; CD40 ligand; IGM; IMD3; TRAP; gp39; CD154; CD40L; HIGM1; T-BAM; TNFSF5; hCD40L; CD40 ligand; CD40 antigen ligand; CD40-L; T-B cell-activating molecule; T-cell antigen Gp39; TNF-related activation protein; tumor necrosis factor (ligand) superfamily member 5 |
Gene ID | 959 |
mRNA Refseq | NM_000074 |
Protein Refseq | NP_000065 |
MIM | 300386 |
UniProt ID | P29965 |
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◆ Native Proteins | ||
CD40LG-30M | Recombinant Monkey CD40LG Protein, Tag Free | +Inquiry |
CD40LG-30H | Recombinant Human CD40LG Protein, Tag Free | +Inquiry |
◆ Cell & Tissue Lysates | ||
CD40LG-1548MCL | Recombinant Mouse CD40LG cell lysate | +Inquiry |
CD40LG-1205RCL | Recombinant Rat CD40LG cell lysate | +Inquiry |
CD40LG-001CCL | Recombinant Canine CD40LG cell lysate | +Inquiry |
CD40LG-1080CCL | Recombinant Cynomolgus CD40LG cell lysate | +Inquiry |
CD40LG-1965HCL | Recombinant Human CD40LG cell lysate | +Inquiry |
Not For Human Consumption!
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