CFP
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Official Full Name
Complement Factor P
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Overview
This gene encodes a plasma glycoprotein that positively regulates the alternative complement pathway of the innate immune system. This protein binds to many microbial surfaces and apoptotic cells and stabilizes the C3- and C5-convertase enzyme complexes in a feedback loop that ultimately leads to formation of the membrane attack complex and lysis of the target cell. Mutations in this gene result in two forms of properdin deficiency, which results in high susceptibility to meningococcal infections. Multiple alternatively spliced variants, encoding the same protein, have been identified. -
Synonyms
complement factor properdin; BFD; PFC; PFD; CFP; properdin; OTTHUMP00000216155; OTTHUMP00000023223; properdin P factor,complement; complement factor P;
- Native Proteins
- Recombinant Proteins
- Cell & Tissue Lysates
- Fluorescent Proteins
- Cyan
- E. coli
- Human
- Mouse
- Rat
- Rhesus monkey
- Zebrafish
- E. coli
- E.coli
- HEK293
- In Vitro Cell Free System
- Mammalian
- Mammalian Cell
- Normal human serum (shown by certified tests to be negative for HBsAg, HTLV-I/II, STS, and for antibodies to HCV, HIV-1 and HIV-II)
- Wheat Germ
- Yeast
- GST
- His
- Myc
- His|T7
- N/A
- N
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | CFP-106H | Active Native Human Complement Factor P (Properdin) | Normal human serum (shown by certified tests to be negative for HBsAg, HTLV-I/II, STS, and for antibodies to HCV, HIV-1 and HIV-II) | N/A |
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| Human | CFP-1179H | Recombinant Human CFP Protein, GST-Tagged | Wheat Germ | GST |
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| Human | CFP-252H | Recombinant Human CFP, His-tagged | E.coli | His | 28-469aa |
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| Human | CFP-29037TH | Recombinant Human CFP | Wheat Germ | N/A | 122 amino acids |
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| Human | CFP-7679H | Recombinant Human CFP protein, His & T7-tagged | E.coli | His/T7 | Gln65~Cys190 (Accession # P27918) |
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| Human | CFP-7552HCL | Recombinant Human CFP 293 Cell Lysate | HEK293 | N/A |
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| Human | CFP-1352H | Recombinant Human CFP Protein (Gln65-Cys190), N-His tagged | E.coli | N-His | Gln65-Cys190 |
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| Human | CFP-901H | Recombinant Human CFP protein, His-tagged | HEK293 | His | Asp28-Leu469 |
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| Human | CFP-3299HF | Recombinant Full Length Human CFP Protein, GST-tagged | In Vitro Cell Free System | GST | 469 amino acids |
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| Mouse | Cfp-7680M | Recombinant Mouse Cfp protein, His-tagged | E.coli | His | Val310~Pro459 |
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| Mouse | Cfp-5378M | Recombinant Mouse Cfp protein, His-Myc-tagged | Yeast | His/Myc | 23-464aa |
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| Mouse | CFP-210M | Recombinant Mouse CFP protein, His-tagged | HEK293 | His |
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| Mouse | CFP-2152M | Recombinant Mouse CFP Protein (23-464 aa), His-tagged | Yeast | His | 23-464 aa |
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| Mouse | Cfp-769M | Recombinant Mouse Cfp Protein, His-tagged | E.coli | N-His | Ser23-Pro464 |
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| Mouse | Cfp-2691M | Recombinant Mouse Cfp protein, His-tagged | E.coli | His | 23-464aa |
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| Rat | Cfp-770R | Recombinant Rat Cfp Protein, His-tagged | E.coli | N-His | Asp24-Pro465 |
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| Rhesus monkey | CFP-211R | Recombinant Rhesus monkey CFP protein, His-tagged | HEK293 | His | Asp 28-Leu 469 |
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| Cyan | CFP-2906 | Recombinant Cyan Fluorescent Protein, His-tagged | E.coli | His |
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| E. coli | CFP-002E | Recombinant Cyan Fluorescent Protein, His-tagged | E. coli | His | ||
| Zebrafish | CFP-7470Z | Recombinant Zebrafish CFP | Mammalian Cell | His |
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| CFP-140 | Recombinant Cyan Fluorescent Protein | E.coli | N/A | 234 aa |
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| CFP-142 | Recombinant Cyan Fluorescent Protein | Mammalian | N/A | 233 aa |
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| CFP-144 | Recombinant Cyan Fluorescent Protein | E.coli | N/A | 234 aa |
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| CFP-141 | Recombinant Cyan Fluorescent Protein | E.coli | N/A | 237 aa |
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| CFP-187 | Recombinant Cyan Fluorescent Protein, His-tagged | E.coli | N/A |
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- Involved Pathway
- Protein Function
- Interacting Protein
- CFP Related Articles
CFP involved in several pathways and played different roles in them. We selected most pathways CFP participated on our site, such as Herpes simplex infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with CFP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Herpes simplex infection | MAP3K7;TLR9;HLA-DRB1;IFNA1;OAS1;C3A.2;EIF2S1B;JAK2B;TAP1 |
CFP has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by CFP itself. We selected most functions CFP had, and list some proteins which have the same functions with CFP. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
CFP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CFP here. Most of them are supplied by our site. Hope this information will be useful for your research of CFP.
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- Q&As
- Reviews
Q&As (5)
Ask a questionYes, genetic factors can influence CFP protein levels, and certain genetic variants may increase the risk of complement-related disorders.
Yes, altered CFP protein levels are associated with several diseases, and measuring these levels can aid in diagnosis.
Some clinical trials may be investigating the use of CFP protein or related therapies for specific diseases. You can check clinical trial databases for current studies.
Research has explored the use of CFP protein and other complement system components in the context of COVID-19, but their clinical use is still under investigation.
CFP protein can be produced through recombinant DNA technology or extracted from human plasma for clinical applications.
Customer Reviews (3)
Write a reviewThey actively engage with the scientific community, staying up-to-date with the latest advancements related to CFP protein and sharing this valuable information.
To summarize, the CFP protein provided by the manufacturer is of exceptional quality and perfectly aligns with my experimental requirements.
This reliable supply chain management guarantees uninterrupted access to the protein, allowing me to plan and conduct my experiments with confidence and without concern for availability issues.
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