Recombinant Human CFP protein, His & T7-tagged

Cat.No. : CFP-7679H
Product Overview : Recombinant Human CFP aa. (Gln65~Cys190 (Accession # P27918)) fused with N-terminal His & T7 tag was produced in E. coli cells.
Description : This gene encodes a plasma glycoprotein that positively regulates the alternative complement pathway of the innate immune system. This protein binds to many microbial surfaces and apoptotic cells and stabilizes the C3- and C5-convertase enzyme complexes in a feedback loop that ultimately leads to formation of the membrane attack complex and lysis of the target cell. Mutations in this gene result in two forms of properdin deficiency, which results in high susceptibility to meningococcal infections. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Source : E. coli
Species : Human
Tag : His & T7
Form : Freeze-dried powder
Molecular Mass : Predicted Molecular Mass: 17.4kDa
Protein length : Gln65~Cys190 (Accession # P27918)
Endotoxin : <1.0EU per 1µg (determined by the LAL method)
Purity : >90%
Characteristic : The isoelectric point is 8.5.
Applications : SDS-PAGE; WB; ELISA; IP.
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Storage buffer : Supplied as lyophilized form in 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5% trehalose, and preservative.
Reconstitution : Reconstitute in sterile ddH2O.
Gene Name : CFP complement factor properdin [ Homo sapiens (human) ]
Official Symbol : CFP
Synonyms : BFD; PFC; PFD; PROPERDIN; complement factor P; properdin P factor, complement; properdin
Gene ID : 5199
mRNA Refseq : NM_001145252.1
Protein Refseq : NP_001138724.1
UniProt ID : P27918

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