Recombinant Human CFP, His-tagged

• Cat.No.: CFP-2908H
• Product Overview: The protein was expressed as 6*his-tagged fusion protein by E.Coli and puri?ed by Ni-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 120-469aa
• Description: This gene encodes a plasma glycoprotein that positively regulates the alternative complement pathway of the innate immune system. This protein binds to many microbial surfaces and apoptotic cells and stabilizes the C3- and C5-convertase enzyme complexes in a feedback loop that ultimately leads to formation of the membrane attack complex and lysis of the target cell. Mutations in this gene result in two forms of properdin deficiency, which results in high susceptibility to meningococcal infections. Multiple alternatively spliced variants, encoding the same protein, have been identified.
• Source: E. coli
• Species: Human
• Tag: His
• Storage: The protein is stored in PBS bu?er at -20 oC. Repeated freezethaw cycles should be avoided.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: CFP?complement factor properdin [?Homo sapiens?(human) ]
• Official Symbol: CFP
• Synonyms: CFP; BFD; PFC; PFD; PROPERDIN; complement factor properdin; properdin; complement factor P; properdin P factor, complement
• Gene ID: 5199
• mRNA Refseq: NM_001145252
• Protein Refseq: NP_001138724
• MIM: 300383
• UniProt ID: P27918
• Chromosome Location: Xp11.4
• Pathway: Herpes simplex infection