CLEC2D
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Official Full Name
C-type lectin domain family 2, member D
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Overview
This gene encodes a member of the natural killer cell receptor C-type lectin family. The encoded protein inhibits osteoclast formation and contains a transmembrane domain near the N-terminus as well as the C-type lectin-like extracellular domain. Several alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Oct 2010] -
Synonyms
CLEC2D; C-type lectin domain family 2, member D; CLAX; LLT1; OCIL; C-type lectin domain family 2 member D; LLT-1; C-type lectin related f; lectin-like transcript 1; lectin-like NK cell receptor; osteoclast inhibitory lectin; C-type lectin superfamily 2, member D;
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Cell & Tissue Lysates
- Human
- Mouse
- Rat
- E.coli
- HEK293
- HEK293T
- Human Cell
- In Vitro Cell Free System
- Mammalian Cell
- Mammalian cells
- Wheat Germ
- Fc
- Avi
- Flag
- GST
- His
- mFc
- Myc
- DDK
- Non
- Involved Pathway
- Protein Function
- Interacting Protein
- Other Resource
CLEC2D involved in several pathways and played different roles in them. We selected most pathways CLEC2D participated on our site, such as Adaptive Immune System, Immune System, Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell, which may be useful for your reference. Also, other proteins which involved in the same pathway with CLEC2D were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Adaptive Immune System | ASB18;CD300C;CD160;RAET1E;UBE2L6;CLEC2H;AGO1;UFL1;TPP2 |
Immune System | MB21D1;RNF123;ART1;SIGLEC12;GAN;KIF26A;CXADR;KLHL21;IgG3 |
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | CD300E;SIGLEC7;CD96;Siglece;KLRB1F;SIGLEC10;TREML4;MICA;CD300C |
CLEC2D has several biochemical functions, for example, carbohydrate binding, transmembrane signaling receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CLEC2D itself. We selected most functions CLEC2D had, and list some proteins which have the same functions with CLEC2D. You can find most of the proteins on our site.
Function | Related Protein |
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carbohydrate binding | CLEC4F;ILLR1;PRG2;ASGR2;OS9;FBXO6;CD209B;CD72;CLEC3A |
transmembrane signaling receptor activity | ANTXR1;IL27RA;SIGLEC8;ERBB2;FCAMR;TNFRSF10D;AGER;IL11RA;MARCO |
CLEC2D has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CLEC2D here. Most of them are supplied by our site. Hope this information will be useful for your research of CLEC2D.
Research Area
- Reviews
- Q&As
Customer Reviews (3)
Write a reviewTheir commitment to delivering exceptional products and assisting with any challenges that may arise ensures a successful and rewarding experimental journey.
This flexibility enables researchers like myself to tailor CLEC2D protein experiments to our unique needs, enhancing the reliability and relevance of the obtained results.
The CLEC2D protein offered by the manufacturer is of exceptional quality, and it meets the rigorous standards necessary for my experimental needs.
Q&As (5)
Ask a questionHLA-DMA's role in antigen presentation is relevant to vaccine development, as it impacts the immune response generated by vaccines and influences the effectiveness of vaccination strategies.
Understanding HLA-DMA's role is crucial in transplantation, as it affects the presentation of antigens from the graft, influencing the immune response and the likelihood of graft acceptance or rejection.
HLA-DMA facilitates the loading of antigenic peptides onto MHC class II molecules, a process essential for the activation of CD4+ T cells and the adaptive immune response.
Aberrant antigen presentation mediated by HLA-DMA has been implicated in autoimmune diseases, as it may lead to the presentation of self-antigens and the activation of autoreactive T cells.
Abnormalities in HLA-DMA expression or function may serve as biomarkers in disease diagnosis, providing insights into the dysregulation of antigen presentation pathways.
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