Recombinant Human CLEC2D Protein, Myc/DDK-tagged, C13 and N15-labeled
Cat.No. : | CLEC2D-6077H |
Product Overview : | CLEC2D MS Standard C13 and N15-labeled recombinant protein (NP_001004419) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
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Description : | This gene encodes a member of the natural killer cell receptor C-type lectin family. The encoded protein inhibits osteoclast formation and contains a transmembrane domain near the N-terminus as well as the C-type lectin-like extracellular domain. Several alternatively spliced transcript variants have been identified for this gene. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc&DDK |
Molecular Mass : | 22.1 kDa |
AA Sequence : | MHDSNNVEKDITPSELPANPGCLHS KEHSIKATLIWRLFFLIMFLTIIVC GMVAALSAIRANCHQEPSVCLQAAC PESWIGFQRKCFYFSDDTKNWTSSQ RFCDSQDADLAQVESFQELNFLLRY KGPSDHWIGLSREQGQPWKWINGTE WTRQLVMKEDGANLYVAKVSQVPRM NPRPVMVSYPGSRRVCLFETRTRPL EQKLISEEDLAANDILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name : | CLEC2D C-type lectin domain family 2 member D [ Homo sapiens (human) ] |
Official Symbol : | CLEC2D |
Synonyms : | CLEC2D; C-type lectin domain family 2, member D; C type lectin superfamily 2, member D; C-type lectin domain family 2 member D; C type lectin related f; CLAX; lectin like transcript 1; LLT1; OCIL; LLT-1; C-type lectin related f; lectin-like transcript 1; lectin-like NK cell receptor; osteoclast inhibitory lectin; C-type lectin superfamily 2, member D; |
Gene ID : | 29121 |
mRNA Refseq : | NM_001004419 |
Protein Refseq : | NP_001004419 |
MIM : | 605659 |
UniProt ID : | Q9UHP7 |
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Clec2d-7853M | Recombinant Mouse Clec2d protein, His-tagged | +Inquiry |
CLEC2D-3236H | Recombinant Human CLEC2D Protein, MYC/DDK-tagged | +Inquiry |
CLEC2D-1464H | Recombinant Human CLEC2D Protein, GST-tagged | +Inquiry |
◆ Lysates | ||
CLEC2D-737RCL | Recombinant Rat CLEC2D cell lysate | +Inquiry |
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Not For Human Consumption!
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Customer Reviews (3)
Write a reviewTheir commitment to delivering exceptional products and assisting with any challenges that may arise ensures a successful and rewarding experimental journey.
This flexibility enables researchers like myself to tailor CLEC2D protein experiments to our unique needs, enhancing the reliability and relevance of the obtained results.
The CLEC2D protein offered by the manufacturer is of exceptional quality, and it meets the rigorous standards necessary for my experimental needs.
Q&As (5)
Ask a questionHLA-DMA's role in antigen presentation is relevant to vaccine development, as it impacts the immune response generated by vaccines and influences the effectiveness of vaccination strategies.
Understanding HLA-DMA's role is crucial in transplantation, as it affects the presentation of antigens from the graft, influencing the immune response and the likelihood of graft acceptance or rejection.
HLA-DMA facilitates the loading of antigenic peptides onto MHC class II molecules, a process essential for the activation of CD4+ T cells and the adaptive immune response.
Aberrant antigen presentation mediated by HLA-DMA has been implicated in autoimmune diseases, as it may lead to the presentation of self-antigens and the activation of autoreactive T cells.
Abnormalities in HLA-DMA expression or function may serve as biomarkers in disease diagnosis, providing insights into the dysregulation of antigen presentation pathways.
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