Recombinant Mouse CLEC2D protein, His-tagged

• Cat.No.: CLEC2D-328M
• Product Overview: Recombinant Mouse CLEC2D protein is produced by our Mammalian expression system and the target gene encoding Leu63-Ser207 is expressed with a 6His tag at the N-terminus.

Specification

• Source: HEK293
• Species: Mouse
• Tag: His
• Form: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
• Protein length: Leu63-Ser207
• Endotoxin: Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
• Purity: Greater than 95% as determined by reducing SDS-PAGE.
• Storage: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
  Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
  Aliquots of reconstituted samples are stable at < -20°C for 3 months.
• Reconstitution: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
  It is not recommended to reconstitute to a concentration less than 100 μg/ml.
  Dissolve the lyophilized protein in distilled water.
  Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Gene Information

• Gene Name: Clec2d C-type lectin domain family 2, member d [ Mus musculus ]
• Official Symbol: CLEC2D
• Synonyms: CLEC2D; C-type lectin domain family 2, member d; C-type lectin domain family 2 member D; osteoclast inhibitory lectin; C-type lectin-related protein B; lectin-like transmembrane protein; C-type lectin-domain family 2 member D; Clrb; Ocil; Clr-b; MGC123478
• Gene ID: 93694
• mRNA Refseq: NM_053109
• Protein Refseq: NP_444339

Reviews

06/24/2021

Their commitment to delivering exceptional products and assisting with any challenges that may arise ensures a successful and rewarding experimental journey.

08/29/2020

This flexibility enables researchers like myself to tailor CLEC2D protein experiments to our unique needs, enhancing the reliability and relevance of the obtained results.

11/08/2018

The CLEC2D protein offered by the manufacturer is of exceptional quality, and it meets the rigorous standards necessary for my experimental needs.

Q&As

How does HLA-DMA contribute to the development of vaccines?

HLA-DMA's role in antigen presentation is relevant to vaccine development, as it impacts the immune response generated by vaccines and influences the effectiveness of vaccination strategies.

In transplantation, how does HLA-DMA impact graft acceptance or rejection?

Understanding HLA-DMA's role is crucial in transplantation, as it affects the presentation of antigens from the graft, influencing the immune response and the likelihood of graft acceptance or rejection.

How does HLA-DMA contribute to the adaptive immune response?

HLA-DMA facilitates the loading of antigenic peptides onto MHC class II molecules, a process essential for the activation of CD4+ T cells and the adaptive immune response.

How does HLA-DMA relate to autoimmune diseases?

Aberrant antigen presentation mediated by HLA-DMA has been implicated in autoimmune diseases, as it may lead to the presentation of self-antigens and the activation of autoreactive T cells.

Can HLA-DMA be used as a biomarker in disease diagnosis?

Abnormalities in HLA-DMA expression or function may serve as biomarkers in disease diagnosis, providing insights into the dysregulation of antigen presentation pathways.