Recombinant Full Length Human CLEC2D Protein, C-Flag-tagged

Cat.No. : CLEC2D-612HFL
Product Overview : Recombinant Full Length Human CLEC2D Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.
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Description : This gene encodes a member of the natural killer cell receptor C-type lectin family. The encoded protein inhibits osteoclast formation and contains a transmembrane domain near the N-terminus as well as the C-type lectin-like extracellular domain. Several alternatively spliced transcript variants have been identified for this gene.
Source : Mammalian cells
Species : Human
Tag : Flag
Form : 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass : 22.1 kDa
AA Sequence : MHDSNNVEKDITPSELPANPGCLHS KEHSIKATLIWRLFFLIMFLTIIVC GMVAALSAIRANCHQEPSVC LQAACPESWIGFQRKCFYFSDDTKN WTSSQRFCDSQDADLAQVESFQELN FLLRYKGPSDHWIGLSREQG
QPWKWINGTEWTRQLVMKEDGANLY VAKVSQVPRMNPRPVMVSYPGSRRV CLFETRTRPLEQKLISEEDLAANDI LDYKDDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining.
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade.
Concentration : >50 ug/mL as determined by microplate BCA method.
Preparation : Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Protein Families : Druggable Genome, Transmembrane
Gene Name : CLEC2D C-type lectin domain family 2 member D [ Homo sapiens (human) ]
Official Symbol : CLEC2D
Synonyms : CLAX; LLT1; OCIL
Gene ID : 29121
mRNA Refseq : NM_001004419.5
Protein Refseq : NP_001004419.1
MIM : 605659
UniProt ID : Q9UHP7

Not For Human Consumption!

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06/24/2021

    Their commitment to delivering exceptional products and assisting with any challenges that may arise ensures a successful and rewarding experimental journey.

    08/29/2020

      This flexibility enables researchers like myself to tailor CLEC2D protein experiments to our unique needs, enhancing the reliability and relevance of the obtained results.

      11/08/2018

        The CLEC2D protein offered by the manufacturer is of exceptional quality, and it meets the rigorous standards necessary for my experimental needs.

        Q&As (5)

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        How does HLA-DMA contribute to the development of vaccines? 01/13/2023

        HLA-DMA's role in antigen presentation is relevant to vaccine development, as it impacts the immune response generated by vaccines and influences the effectiveness of vaccination strategies.

        In transplantation, how does HLA-DMA impact graft acceptance or rejection? 05/18/2021

        Understanding HLA-DMA's role is crucial in transplantation, as it affects the presentation of antigens from the graft, influencing the immune response and the likelihood of graft acceptance or rejection.

        How does HLA-DMA contribute to the adaptive immune response? 06/21/2019

        HLA-DMA facilitates the loading of antigenic peptides onto MHC class II molecules, a process essential for the activation of CD4+ T cells and the adaptive immune response.

        How does HLA-DMA relate to autoimmune diseases? 11/26/2018

        Aberrant antigen presentation mediated by HLA-DMA has been implicated in autoimmune diseases, as it may lead to the presentation of self-antigens and the activation of autoreactive T cells.

        Can HLA-DMA be used as a biomarker in disease diagnosis? 05/27/2017

        Abnormalities in HLA-DMA expression or function may serve as biomarkers in disease diagnosis, providing insights into the dysregulation of antigen presentation pathways.

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