Recombinant Full Length Human CLEC2D Protein, C-Flag-tagged
Cat.No. : | CLEC2D-612HFL |
Product Overview : | Recombinant Full Length Human CLEC2D Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells. |
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Description : | This gene encodes a member of the natural killer cell receptor C-type lectin family. The encoded protein inhibits osteoclast formation and contains a transmembrane domain near the N-terminus as well as the C-type lectin-like extracellular domain. Several alternatively spliced transcript variants have been identified for this gene. |
Source : | Mammalian cells |
Species : | Human |
Tag : | Flag |
Form : | 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 22.1 kDa |
AA Sequence : | MHDSNNVEKDITPSELPANPGCLHS KEHSIKATLIWRLFFLIMFLTIIVC GMVAALSAIRANCHQEPSVC LQAACPESWIGFQRKCFYFSDDTKN WTSSQRFCDSQDADLAQVESFQELN FLLRYKGPSDHWIGLSREQG QPWKWINGTEWTRQLVMKEDGANLY VAKVSQVPRMNPRPVMVSYPGSRRV CLFETRTRPLEQKLISEEDLAANDI LDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining. |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade. |
Concentration : | >50 ug/mL as determined by microplate BCA method. |
Preparation : | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Protein Families : | Druggable Genome, Transmembrane |
Gene Name : | CLEC2D C-type lectin domain family 2 member D [ Homo sapiens (human) ] |
Official Symbol : | CLEC2D |
Synonyms : | CLAX; LLT1; OCIL |
Gene ID : | 29121 |
mRNA Refseq : | NM_001004419.5 |
Protein Refseq : | NP_001004419.1 |
MIM : | 605659 |
UniProt ID : | Q9UHP7 |
Products Types
◆ Recombinant Protein | ||
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CLEC2D-3236H | Recombinant Human CLEC2D Protein, MYC/DDK-tagged | +Inquiry |
Clec2d-547R | Recombinant Rat Clec2d protein(Lys98-Leu233), hFc-tagged | +Inquiry |
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◆ Lysates | ||
CLEC2D-737RCL | Recombinant Rat CLEC2D cell lysate | +Inquiry |
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Not For Human Consumption!
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Customer Reviews (3)
Write a reviewTheir commitment to delivering exceptional products and assisting with any challenges that may arise ensures a successful and rewarding experimental journey.
This flexibility enables researchers like myself to tailor CLEC2D protein experiments to our unique needs, enhancing the reliability and relevance of the obtained results.
The CLEC2D protein offered by the manufacturer is of exceptional quality, and it meets the rigorous standards necessary for my experimental needs.
Q&As (5)
Ask a questionHLA-DMA's role in antigen presentation is relevant to vaccine development, as it impacts the immune response generated by vaccines and influences the effectiveness of vaccination strategies.
Understanding HLA-DMA's role is crucial in transplantation, as it affects the presentation of antigens from the graft, influencing the immune response and the likelihood of graft acceptance or rejection.
HLA-DMA facilitates the loading of antigenic peptides onto MHC class II molecules, a process essential for the activation of CD4+ T cells and the adaptive immune response.
Aberrant antigen presentation mediated by HLA-DMA has been implicated in autoimmune diseases, as it may lead to the presentation of self-antigens and the activation of autoreactive T cells.
Abnormalities in HLA-DMA expression or function may serve as biomarkers in disease diagnosis, providing insights into the dysregulation of antigen presentation pathways.
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