Recombinant Mouse Clec2d protein, His-tagged

• Cat.No.: Clec2d-7853M
• Product Overview: Recombinant Mouse Clec2d protein(Q91V08)(63-207aa), fused with N-terminal His tag, was expressed in E.coli.

Specification

• Source: E.coli
• Species: Mouse
• Tag: His
• Protein length: 63-207aa
• Form: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
• Molecular Mass: 21.2 kDa
• AASequence: LSATKTEQIPVNKTYAACPQNWIGV ENKCFYFSEYPSNWTFAQAFCMAQE AQLARFDNQDELNFLMRYKANFDSW IGLHRESSEHPWKWTDNTEYNNTIP IRGEERFAYLNNNGISSTRIYSLRM WICSKLNSYSLHCQTPFFPS
• Purity: Greater than 85% as determined by SDS-PAGE.
• Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
• Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C.

Gene Information

• Gene Name: Clec2d C-type lectin domain family 2, member d [ Mus musculus ]
• Official Symbol: Clec2d
• Synonyms: CLEC2D; C-type lectin domain family 2, member d; C-type lectin domain family 2 member D; osteoclast inhibitory lectin; C-type lectin-related protein B; lectin-like transmembrane protein; C-type lectin-domain family 2 member D; Clrb; Ocil; Clr-b; MGC123478
• Gene ID: 93694
• mRNA Refseq: NM_053109
• Protein Refseq: NP_444339

Reviews

06/24/2021

Their commitment to delivering exceptional products and assisting with any challenges that may arise ensures a successful and rewarding experimental journey.

08/29/2020

This flexibility enables researchers like myself to tailor CLEC2D protein experiments to our unique needs, enhancing the reliability and relevance of the obtained results.

11/08/2018

The CLEC2D protein offered by the manufacturer is of exceptional quality, and it meets the rigorous standards necessary for my experimental needs.

Q&As

How does HLA-DMA contribute to the development of vaccines?

HLA-DMA's role in antigen presentation is relevant to vaccine development, as it impacts the immune response generated by vaccines and influences the effectiveness of vaccination strategies.

In transplantation, how does HLA-DMA impact graft acceptance or rejection?

Understanding HLA-DMA's role is crucial in transplantation, as it affects the presentation of antigens from the graft, influencing the immune response and the likelihood of graft acceptance or rejection.

How does HLA-DMA contribute to the adaptive immune response?

HLA-DMA facilitates the loading of antigenic peptides onto MHC class II molecules, a process essential for the activation of CD4+ T cells and the adaptive immune response.

How does HLA-DMA relate to autoimmune diseases?

Aberrant antigen presentation mediated by HLA-DMA has been implicated in autoimmune diseases, as it may lead to the presentation of self-antigens and the activation of autoreactive T cells.

Can HLA-DMA be used as a biomarker in disease diagnosis?

Abnormalities in HLA-DMA expression or function may serve as biomarkers in disease diagnosis, providing insights into the dysregulation of antigen presentation pathways.