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Official Full Name chemokine (C-X-C motif) receptor 5
Background This gene encodes a multi-pass membrane protein that belongs to the CXC chemokine receptor family. It is expressed in mature B-cells and Burkitts lymphoma. This cytokine receptor binds to B-lymphocyte chemoattractant (BLC), and is involved in B-cell migration into B-cell follicles of spleen and Peyer patches. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]
Synonyms CXCR5; chemokine (C-X-C motif) receptor 5; BLR1; CD185; MDR15; C-X-C chemokine receptor type 5; CXC-R5; CXCR-5; MDR-15; monocyte-derived receptor 15; Burkitt lymphoma receptor 1, GTP-binding protein; Burkitt lymphoma receptor 1, GTP binding protein (chemokine (C-X-C motif) receptor 5);
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Source :
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CXCR5-426HCL Recombinant Human CXCR5 cell lysate N/A
    Human CXCR5-9162H Recombinant Human CXCR5 Wheat Germ N/A
    Human CXCR5-9163H Recombinant Human CXCR5, GST-tagged Wheat Germ GST
    Mouse CXCR5-4111M Recombinant Mouse CXCR5 Protein Mammalian Cell His
    Rat CXCR5-1695R Recombinant Rat CXCR5 Protein Mammalian Cell His
    Chicken CXCR5-2601C Recombinant Chicken CXCR5 Mammalian Cell His
    Kit-1060 HIV-1 Protease Assay Kit N/A
    Kit-1200 CXCR5 (BLR1) CHO-K1 β-Arrestin GPCR Assay Kit N/A
    Kit-1201 CHO-K1 CXCR5 Bioassay Kit N/A
    Kit-1202 cAMP CXCR5 (BLR1) CHO-K1 GPCR Assay Kit N/A

    CXCR5 involved in several pathways and played different roles in them. We selected most pathways CXCR5 participated on our site, such as Cytokine-cytokine receptor interaction, Chemokine signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with CXCR5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cytokine-cytokine receptor interaction CXCL8; IL5RA; IFNA7; OSTN; CXCL10; GHRA; IL3; CCL4L2; TNFRSF25; IFNE
    Chemokine signaling pathway PRKACA; CCL28; CXCL2; PF4V1; PARD3; CXCR1; IKBKG; CXCL9; PRKACG; PLCB4

    CXCR5 has several biochemical functions, for example, C-X-C chemokine receptor activity, G-protein coupled receptor activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CXCR5 itself. We selected most functions CXCR5 had, and list some proteins which have the same functions with CXCR5. You can find most of the proteins on our site.

    Function Related Protein
    C-X-C chemokine receptor activity CCBP2; CXCR2; CXCR5; CXCR4B; CXCR7; CXCR6; CXCR4; CCR9A; CXCR4A; CXCR3
    G-protein coupled receptor activity GPR68; GPR119; TAAR8A; OR12D2; OLFR476; FZD7; LPAR1; MRGPRX2; F2R; GRM6A
    protein binding S100A4; GATC; GOLSYN; LRFN2; FAM107A; ZNF295; ERCC6L; NR1H4; TNFAIP1; AJUBA

    CXCR5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CXCR5 here. Most of them are supplied by our site. Hope this information will be useful for your research of CXCR5.


    Klimatcheva, E; Pandina, T; et al. CXCL13 antibody for the treatment of autoimmune disorders. BMC IMMUNOLOGY 16:-(2015).
    Spaan, M; Kreefft, K; et al. CD4(+)CXCR5(+) T cells in chronic HCV infection produce less IL-21, yet are efficient at supporting B cell responses. JOURNAL OF HEPATOLOGY 62:303-310(2015).

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